Total Body Mass, Fat Mass, Fat-Free Mass, and Skeletal Muscle in Older People: Cross-Sectional Differences in 60-Year-Old Persons

2001 ◽  
Vol 49 (12) ◽  
pp. 1633-1640 ◽  
Author(s):  
Ursula G. Kyle ◽  
Laurence Genton ◽  
Didier Hans ◽  
Veronique L. Karsegard ◽  
Jean-Pierre Michel ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Older People ◽  
Body Mass ◽  
Fat Mass ◽  
Fat Free Mass ◽  
Cross Sectional ◽  
Total Body Mass ◽  
Total Body

One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women

2003 ◽  
Vol 94 (6) ◽  
pp. 2368-2374 ◽  
Author(s):  
Marjolein Visser ◽  
Marco Pahor ◽  
Frances Tylavsky ◽  
Stephen B. Kritchevsky ◽  
Jane A. Cauley ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Mass ◽  
Fat Mass ◽  
Population Based ◽  
Fat Free Mass ◽  
Simultaneous Increase ◽  
Total Body Mass ◽  
Men And Women ◽  
Total Body

Changing body composition has been suggested as a pathway to explain age-related functional decline. No data are available on the expected changes in body composition as measured by dual-energy X-ray absorptiometry (DXA) in a population-based cohort of older persons. Body composition data at baseline, 1-yr follow-up, and 2-yr follow-up was measured by DXA in 2,040 well-functioning black and white men and women aged 70–79 yr, participants of the Health, Aging, and Body Composition Study. After 2 yr, a small decline in total body mass was observed (men: −0.3%, women: −0.4%). Among men, fat-free mass and appendicular lean soft tissue mass (ALST) decreased by −1.1 and −0.8%, respectively, which was masked by a simultaneous increase in total fat mass (+2.0%). Among women, a decline in fat-free mass was observed after 2 yr only (−0.6%) with no change in ALST and body fat mass. After 2 yr, the decline in ALST was greater in blacks than whites. Change in total body mass was associated with change in ALST ( r = +0.58 to +0.70; P < 0.0001). Among participants who lost total body mass, men lost relatively more ALST than women, and blacks lost relatively more ALST than whites. In conclusion, the mean change in body composition after a 1- to 2-yr follow-up was 1–2% with a high interindividual variability. Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss.

scholarly journals Accounting for height in indices of body composition during childhood and adolescence

2019 ◽  
Vol 4 ◽  
pp. 105 ◽  
Author(s):  
Linda M. O'Keeffe ◽  
Abigail Fraser ◽  
Laura D. Howe
Keyword(s):  
Body Composition ◽  
Cohort Study ◽  
Body Mass ◽  
Fat Mass ◽  
Early Life ◽  
Fat Free Mass ◽  
Childhood And Adolescence ◽  
Total Body Mass ◽  
Total Body ◽  
Age And Sex

Correlations of body composition with height vary by age and sex during childhood. Standard approaches to accounting for height in measures of body composition (dividing by height (in meters)2) do not take this into account. Using measures of total body mass (TBM), fat mass (FM) and fat free mass (FFM) at ages nine, 11, 13, 15 and 18 years from a longitudinal UK cohort study (ALSPAC), we calculated indices of body composition at each age by dividing measures by height (in meters)2. We then produced age-and sex-specific powers of height using allometric regressions and calculated body composition indices by dividing measures by height raised to these powers. TBM, FM and FFM divided by height2 were correlated with height up-to age 11 in females. In males, TBM and FM divided by height2 were correlated with height up-to age 15 years while FM divided by height2 was correlated with height up-to age 11 years. Indices of body composition using age-and sex-specific powers were not correlated with height at any age. In early life, age-and sex-specific powers of height, rather than height in meters2, should be used to adjust body composition for height when measures of adiposity/mass independent of height are required.

Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image

2004 ◽  
Vol 97 (6) ◽  
pp. 2333-2338 ◽  
Author(s):  
Wei Shen ◽  
Mark Punyanitya ◽  
ZiMian Wang ◽  
Dympna Gallagher ◽  
Marie-Pierre St.-Onge ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Body Mass Index ◽  
Adipose Tissue ◽  
Magnetic Resonance ◽  
Body Mass ◽  
Whole Body ◽  
Intervertebral Space ◽  
Cross Sectional ◽  
Abdominal Image ◽  
Total Body

A single abdominal cross-sectional computerized axial tomography and magnetic resonance image is often obtained in studies examining adipose tissue (AT) distribution. An abdominal image might also provide additional useful information on total body skeletal muscle (SM) and AT volumes with related physiological insights. We therefore investigated the relationships between abdominal SM and AT areas from single images and total body component volumes in a large and diverse sample of healthy adult subjects. Total body SM and AT volumes were derived by whole body multislice magnetic resonance imaging in 123 men [age (mean ± SD) of 41.6 ± 15.8 yr; body mass index of 25.9 ± 3.4 kg/m2] and 205 women (age of 47.8 ± 18.7 yr; body mass index of 26.7 ± 5.6 kg/m2). Single abdominal SM and AT slice areas were highly correlated with total body SM ( r = 0.71–0.92; r = 0.90 at L4–L5 intervertebral space) and AT ( r = 0.84–0.96; r = 0.94 at L4–L5 intervertebral space) volumes, respectively. R2 increased by only 5.7–6.1% for SM and 2.7–4.4% for AT with the inclusion of subject sex, age, ethnicity, scanning position, body mass index, and waist circumference in the model. The developed SM and AT models were validated in an additional 49 subjects. To achieve equivalent power to a study measuring total body SM or AT volumes, a study using a single abdominal image would require 17–24% more subjects for SM and 6–12% more subjects for AT. Measurement of a single abdominal image can thus provide estimates of total body SM and AT for group studies of healthy adults.

scholarly journals Standardized MET Value Underestimates the Energy Cost of Treadmill Running in Men

2017 ◽  
Vol 38 (12) ◽  
pp. 890-896
Author(s):  
Helouane Ázara ◽  
Paulo Farinatti ◽  
Adrian Midgley ◽  
Fabrício Vasconcellos ◽  
Patrícia Vigário ◽  
...  
Keyword(s):  
Body Mass ◽  
Energy Cost ◽  
Fat Free Mass ◽  
Treadmill Running ◽  
Metabolic Equivalent ◽  
Total Body Mass ◽  
Healthy Men ◽  
Energy Cost Of Running ◽  
The Mean ◽  
Total Body

AbstractThe main purpose of the present study was to compare the reference metabolic equivalent (MET) value and observed resting oxygen uptake (VO2) for defining cardiorespiratory fitness (VO2max) and characterizing the energy cost of treadmill running. A heterogeneous cohort of 114 healthy men volunteered to participate. In Part 1 of the study, 114 men [mean±SD, age: 24±5 years; height: 177.1±7.9 cm; body mass: 75.0±10.0 kg] visited the laboratory twice for assessment of resting and maximal VO2 values to compare the reference MET value vs. observed resting VO2 and to investigate the association between resting VO2 and VO2max. In Part 2, 14 of the 114 men visited the laboratory once more to perform a 30-min bout of running at 8.0 km∙h−1/8.3 METs. The mean observed resting VO2 of 3.26 mL·kg−1·min−1 was lower than the reference MET value of 3.5 mL·kg−1·min−1 (P<0.001). Resting and maximal VO2 values relative to total body mass and fat-free mass were positively correlated (R=0.71 and 0.60, respectively; P<0.001). The maximal MET and energy cost of treadmill running were consequently underestimated when calculated using the reference MET value only for those with low VO2max (P=0.005 to P<0.001). In conclusion, the reference MET value considerably overestimated observed resting VO2 in men with low VO2max, resulting in underestimations of the maximal MET, exercise intensity prescription, and the energy cost of running.

Anamorelin in patients with advanced non-small cell lung cancer and cachexia: Results from the phase III studies ROMANA 1 and 2.

2015 ◽  
Vol 33 (29_suppl) ◽  
pp. 175-175 ◽  
Author(s):  
Jennifer S. Temel ◽  
David Christopher Currow ◽  
Kenneth Fearon ◽  
Ying Yan ◽  
John Friend ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Body Weight ◽  
Small Cell Lung Cancer ◽  
Body Mass ◽  
Fat Mass ◽  
Small Cell ◽  
Small Cell Lung ◽  
Phase 3 ◽  
Total Body Mass ◽  
Total Body

175 Background: Cancer anorexia-cachexia syndrome is common in patients with non-small cell lung cancer (NSCLC). It is characterized by loss of lean body mass (LBM) and negatively impacts quality of life. Anamorelin HCl (ANAM) is a novel investigational ghrelin receptor agonist with anabolic and appetite-enhancing activity. Methods: Two randomized, double-blind, Phase 3 ROMANA 1 (N = 484; NCT01387269) and ROMANA2, (N = 495; NCT01387282) trials assessed ANAM (100 mg) efficacy/safety versus placebo in patients with unresectable stage III/IV NSCLC and cachexia ( ≥ 5% weight loss within prior 6 months or BMI < 20 kg/m2) over 12 weeks. Co-primary endpoints were change from baseline over 12 weeks in LBM and hand grip strength (HGS). Secondary endpoints included changes in body weight and in the anorexia-cachexia subdomain of the Functional Assessment of Anorexia/Cachexia Therapy questionnaire, and pooled survival from ROMANA 1 and 2. Exploratory post-hoc analyses determined change in total body and fat mass from baseline to 12 weeks. Results: Over 12 weeks ANAM significantly increased LBM vs placebo in ROMANA 1 (1.10 vs -0.44 kg, p < 0.001) and ROMANA 2 (0.75 vs -0.96 kg, p < 0.001); HGS was similar in the two arms. In both studies ANAM vs placebo increased body weight (2.20 vs 0.14 kg, p < 0.001; and 0.95 vs -0.57 kg, p < 0.001) and improved anorexia/cachexia symptoms (4.12 vs 1.92, p < 0.001; and 3.48 vs 1.34, p = 0.002). Increases in total body mass (2.87 vs 0.07 kg, p < 0.001; and 2.04 vs -0.59 kg, p < 0.001) and in fat mass (1.21 vs -0.13 kg, p < 0.001; and 0.77 vs 0.09 kg, p = 0.012) were observed for ANAM vs placebo. ANAM was well tolerated; the most frequent drug-related adverse event in ROMANA 1 and 2 was hyperglycemia (5.3% and 4.2%). There was no difference between study arms in median 1-year survival. Conclusions: In two global, Phase 3 studies, ANAM treatment for 12 weeks was well tolerated, and increased LBM, body weight, total body mass and fat mass indicating anabolic activity and suggesting restoration of energy balance in advanced NSCLC patients with cachexia. ANAM also improved anorexia-cachexia symptoms/concerns. Similar pooled survival was observed between the study arms. Clinical trial information: NCT01387269, NCT01387282.

Abstract P261: Associations of Left Ventricular Mass, Total Body Weight, and Fat-Free Mass With Body Mass Index: The Framingham Heart Study

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Philimon N Gona ◽  
Jane J Lee ◽  
Carol J Salton ◽  
Saadia Qazi ◽  
Christopher J O'Donnell ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Left Ventricular Mass ◽  
Body Mass ◽  
Linear Trend ◽  
Left Ventricular ◽  
Fat Free Mass ◽  
Total Body Mass ◽  
Ventricular Mass ◽  
Cardiovascular Morbidity And Mortality ◽  
Total Body

Introduction: Increased left ventricular mass (LVM) predicts excess cardiovascular morbidity and mortality. LVM is often indexed to height (HT) or body surface area (BSA). HT-indexation ignores weight and thus obesity. The relationship of indexed LVM with weight, obesity, and adiposity is unclear. We investigated the association of LVM with total-body mass (TBM, i.e. weight) and fat-free mass (FFM), hypothesizing that LVM scales better to FFM than TBM. Methods: From the 1794 members of Framingham Offspring cohort who underwent cardiac magnetic resonance (CMR), we identified 845 (aged 65±9y) without any history of hypertension, myocardial infarction, heart failure, or CMR wall-motion abnormality. LVM was measured from cine bSSFP images and indexed to HT, BSA, TBM and FFM (by DEXA). Participants were stratified by sex and body mass index (BMI) category (NL=BMI 18.5 - 24.9; OW=25.0 - 29.9; OB=30.0+ kg/m 2 ). We used sex-specific ANCOVA to test for linear trend across BMI categories, and determined sex-specific Pearson correlation coefficients of LVM with BMI; both sets of analyses were adjusted for age and systolic blood pressure. Data are summarized as mean ± SD. Results: The Table shows that LVM and LVM/HT increase with greater BMI-category in both sexes. LVM/BSA was similar across BMI-categories, while LVM/TBM decreased. There was no linear trend across BMI-categories for LVM/FFM in either sex. On a continuous basis, LVM and LVM/HT were positively correlated with BMI in both sexes (r=0.20 to 0.35, p<0.001 for all); LVM/BSA was weakly inversely correlated with BMI in women only (r=-0.14, p=0.001) but not men (r=-0.08, p=0.18); LVM/TBM was inversely correlated with BMI (M: r=-0.39, W: r=-0.54; p<0.0001 both); LVM/FFM was not correlated with BMI in either sex (M: r=-0.05, p=0.38, W: r=0.08, p=0.055). Conclusion: LVM as a proportion of TBM (weight) actually decreases with greater BMI, while LVM/FFM is not associated with BMI. Whether LVM is better scaled to FFM vs HT, BSA or TBM for risk stratification purposes remains to be determined.

scholarly journals The Recovery Phase Following a Triple Iron Triathlon

2009 ◽  
Vol 21 (1) ◽  
pp. 65-74 ◽  
Author(s):  
Beat Knechtle ◽  
Tristan Vinzent ◽  
Steve Kirby ◽  
Patrizia Knechtle ◽  
Thomas Rosemann
Keyword(s):  
Skeletal Muscle ◽  
Body Mass ◽  
Plasma Volume ◽  
Total Body Water ◽  
Skeletal Muscle Mass ◽  
Recovery Phase ◽  
Body Water ◽  
Total Body Mass ◽  
Skeletal Muscle Damage ◽  
Total Body

The Recovery Phase Following a Triple Iron TriathlonThe purpose of this case study was to investigate the recovery phase in a single athlete after a Triple Iron Triathlon involving 11.4 km swimming, 540 km cycling and 126.6 km running. Total body mass, body fat and skeletal muscle mass using the anthropometric method as well as total body water using bioelectrical impedance analysis were determined pre race, after the race and every 24 hours until complete recovery. Parameters of hydration status (urinary specific gravity, hematocrit and plasma sodium) and skeletal muscle damage (plasma urea) were measured at the same time. After finishing the race within 42 hours, total body mass was decreased and total body water was increased. Over the following 6 days, prior to returning to pre race values for plasma volume and total body water, body mass reached a peak value on day 3, plasma volume on day 2 and total body water on day 1. Clinically visible edemas of the feet persisted until day 4. Six days after the race, body mass was reduced by 2.1 kg, skeletal muscle mass by 0.6 kg and fat mass by 0.7 kg. An increase in both blood urea and urinary output post race between days 3 and 6 suggested an impairment of renal function immediately post race due to skeletal muscle damage and manifesting clinically observed edemas. For practical application, athletes, coaches and physicians should anticipate that performing such an ultra-endurance race can lead to considerable edemas of the lower limbs during the recovery phase.

scholarly journals POSTURAL PROFILE OF CLASSICAL BALLERINAS FROM THE VALE DO SÃO FRANCISCO REGION OF BRAZIL

2016 ◽  
Vol 15 (3) ◽  
pp. 199-204
Author(s):  
JANNINI NASCIMENTO RIBEIRO ◽  
UILLA ISLANY SOARES DE MOURA ◽  
LARA RABÊLO MENDES ◽  
BRUNA ANGELA ANTONELLI ◽  
PAULO ADRIANO SCHWINGEL ◽  
...  
Keyword(s):  
Body Mass ◽  
Cross Sectional ◽  
Total Body Mass ◽  
Functional Balance ◽  
Pelvic Inclination ◽  
Postural Changes ◽  
Photogrammetric Method ◽  
The Mean ◽  
Classical Ballet ◽  
Total Body

ABSTRACT Objective: The study aimed to determine the association between postural changes and practice of classical ballet among ballerinas from Integrated Administrative Region of Development (RIDE) in Polo Petrolina/PE and Juazeiro/BA. Methods: Cross-sectional observational study with 19 classical ballerinas aged over 15 years and at least 5 years of uninterrupted classical ballet practice. The anthropometric assessment included measurements of total body mass, height and body mass index (BMI). Postural evaluation was performed using the photogrammetric method with help of Posturograma(r) and SAPO(c) software. Results: The mean age was 25.3±11.7 years and the mean BMI was 21.4±2.9 kg/m². Approximately 74% of classical ballerinas had normal anthropometric profile. The postural profile of the classical ballerinas showed inclination and protrusion of the head, trunk rotation, rectification of cervical lordosis, increased thoracic kyphosis, increased lumbar lordosis, pelvic inclination and anteversion. Conclusion: The practice of ballet led to changes in body alignment of the classical ballerinas evaluated. The results points out to the need of postural re-education in order to contribute for the kinetic-functional balance of classical ballet practitioners.

Sign in / Sign up

Export Citation Format

Share Document