EPIDEMIOLOGICAL STUDIES ON FOOT-AND-MOUTH DISEASE

2010 ◽  
Vol 8 (4) ◽  
pp. 385-414 ◽  
Author(s):  
J. FORSSMAN
Keyword(s):  
Foot And Mouth Disease ◽  
Epidemiological Studies ◽  
Mouth Disease ◽  
Foot And Mouth

scholarly journals Epidemiological studies on the 1967–1968 foot-and-mouth disease epidemic: the reporting of suspected disease

1976 ◽  
Vol 77 (3) ◽  
pp. 299-306 ◽  
Author(s):  
M. E. Hugh-Jones
Keyword(s):  
Disease Activity ◽  
Foot And Mouth Disease ◽  
Epidemiological Studies ◽  
Mouth Disease ◽  
The West ◽  
Daily Number ◽  
Local Disease ◽  
West Midlands ◽  
Foot And Mouth

SUMMARYFrom an analysis of the telephone reports in ten FMD Control Centres in the West Midlands, the veterinary officers' reports on each outbreak, the farm patrol reports and the daily number of outbreaks announced on the 17.50 h B.B.C. T.V. News, it would appear that the reporting of suspected outbreaks was indirectly related to the local disease activity. Private veterinary practitioners reported older cases of FMD at the beginning and end of the epidemic than in the middle.

scholarly journals Onychomadesis outbreak linked to hand, foot, and mouth disease, Spain, July 2008

2010 ◽  
Vol 15 (37) ◽  
Author(s):  
J Guimbao ◽  
P Rodrigo ◽  
M J Alberto ◽  
M Omeñaca
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort ◽  
Strong Association ◽  
Foot And Mouth Disease ◽  
Descriptive Study ◽  
Epidemiological Studies ◽  
Case Definition ◽  
Mouth Disease ◽  
Microbiological Analysis ◽  
Foot And Mouth

In July 2008 an onychomadesis outbreak in a nursery setting was reported in Saragossa (Spain). Some of the cases had previously suffered from hand, foot and mouth disease (HFMD). In order to study the outbreak and to determine the relation between the two diseases, two epidemiological studies were conducted: a descriptive study focused on cases and a retrospective cohort study. Samples from stool, pharynx and nails were obtained from cases for microbiological analysis. During the study period, 27 children fulfilled the case definition. The average age was 1.8 years. A case shed on average four nails (minimum one maximum twelve). Twenty-four of the 27 cases had previously presented with HFMD which started an average of 40 days before the onset of onychomadesis (relative risk: 14). Unidentified non-polio enterovirus (n=10), coxsackie B1 (n=4) and coxsackie B2 virus (n=3) were isolated in 28 specimens obtained from 14 cases. The analysis showed a strong association between HMFD and onychomadesis. Microbiological results have not been conclusive; consequently more studies are necessary to determine the causal agent of infectious onychomadesis.

scholarly journals Serosurveillance of foot-and-mouth disease virus in selected livestock-wildlife interface areas of Tanzania

2014 ◽  
Vol 81 (2) ◽  
Author(s):  
Mathias Mkama ◽  
Christopher J. Kasanga ◽  
Raphael Sallu ◽  
Ezekia Ranga ◽  
Mmeta Yongolo ◽  
...  
Keyword(s):  
National Parks ◽  
Control Strategies ◽  
Foot And Mouth Disease ◽  
Epidemiological Studies ◽  
Mouth Disease ◽  
Transmission Dynamics ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Cattle Herds ◽  
Sera Samples

Foot-and-mouth disease (FMD) is caused by a virus of the genus Aphthorvirus of the family Picornaviridae. There is great scientific need for determining the transmission dynamics of FMD virus (FMDV) by drawing more attention to the livestock-wildlife interface areas. A variety of literature suggests that buffalo could serve as reservoir of FMDV in wildlife and cattle. However, many FMDV research studies conducted on experimentally infected cattle as carriers and groups of animal highly susceptible to FMDV (i.e. bovine calves) have shown lower chances of transmission of the virus between carriers and the susceptible groups. These findings underscore the importance of continued research on the role played by carrier animals on FMDV transmission dynamics under natural conditions. The aim of this research study was to determine FMDV infection status among buffalo and cattle herds in selected livestock-wildlife interface areas. The sampled areas included Mikumi, Mkomazi and Ruaha national parks, where a total of 330 buffalo and bovine sera samples were collected. Laboratory analysis of the samples was done through the NSP ELISA technique using the PrioCHECK® FMDV NS Kit for detection of antibodies directed against 3ABC non-structural proteins and confirming natural infections. Results showed that 76.3% of tested sera samples were positive for FMDV. However, serotyping of NSP ELISA seroreactors with LPBE is yet to be done. This information is important for further epidemiological studies towards developing effective FMD control strategies.

Biophysical Measurement of Molecular Weight of Foot-and-Mouth Disease RNA Fragments

1974 ◽  
Vol 32 ◽  
pp. 262-263
Author(s):  
Sydney S. Breese ◽  
Howard L. Bachrach
Keyword(s):  
Chemical Properties ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Distilled Water ◽  
Bovine Plasma ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Carbon Coated ◽  
Rna Fragments ◽  
Physical And Chemical

Continuing studies on the physical and chemical properties of foot-and-mouth disease virus (FMDV) have included electron microscopy of RNA strands released when highly purified virus (1) was dialyzed against demlneralized distilled water. The RNA strands were dried on formvar-carbon coated electron microscope screens pretreated with 0.1% bovine plasma albumin in distilled water. At this low salt concentration the RNA strands were extended and were stained with 1% phosphotungstic acid. Random dispersions of strands were recorded on electron micrographs, enlarged to 30,000 or 40,000 X and the lengths measured with a map-measuring wheel. Figure 1 is a typical micrograph and Fig. 2 shows the distributions of strand lengths for the three major types of FMDV (A119 of 6/9/72; C3-Rezende of 1/5/73; and O1-Brugge of 8/24/73.

High resolution surface structure of foot-and-mouth disease virus

1978 ◽  
Vol 36 (2) ◽  
pp. 376-377
Author(s):  
S. S. Breese ◽  
H. L. Bachrach
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Surface Structure ◽  
Disease Virus ◽  
Potassium Phosphate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Physical Measurements ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Models for the structure of foot-and-mouth disease virus (FMDV) have been proposed from chemical and physical measurements (Brown, et al., 1970; Talbot and Brown, 1972; Strohmaier and Adam, 1976) and from rotational image-enhancement electron microscopy (Breese, et al., 1965). In this report we examine the surface structure of FMDV particles by high resolution electron microscopy and compare it with that of particles in which the outermost capsid protein VP3 (ca. 30, 000 daltons) has been split into smaller segments, two of which VP3a and VP3b have molecular weights of about 15, 000 daltons (Bachrach, et al., 1975).Highly purified and concentrated type A12, strain 119 FMDV (5 mg/ml) was prepared as previously described (Bachrach, et al., 1964) and stored at 4°C in 0. 2 M KC1-0. 5 M potassium phosphate buffer at pH 7. 5. For electron microscopy, 1. 0 ml samples of purified virus and trypsin-treated virus were dialyzed at 4°C against 0. 2 M NH4OAC at pH 7. 3, deposited onto carbonized formvar-coated copper screens and stained with phosphotungstic acid, pH 7. 3.

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