Indoor air pollution and lung function growth among children in four Chinese cities

Indoor Air ◽  
2011 ◽  
Vol 22 (1) ◽  
pp. 3-11 ◽  
Author(s):  
A. Roy ◽  
R. S. Chapman ◽  
W. Hu ◽  
F. Wei ◽  
X. Liu ◽  
...  
2020 ◽  
Vol 55 (3) ◽  
pp. 1901831 ◽  
Author(s):  
Anke Hüls ◽  
Aneesa Vanker ◽  
Diane Gray ◽  
Nastassja Koen ◽  
Julia L. MacIsaac ◽  
...  

IntroductionIndoor air pollution and maternal smoking during pregnancy are associated with respiratory symptoms in infants, but little is known about the direct association with lung function or interactions with genetic risk factors. We examined associations of exposure to indoor particulate matter with a 50% cut-off aerodynamic diameter of 10 µm (PM10) and maternal smoking with infant lung function and the role of gene–environment interactions.MethodsData from the Drakenstein Child Health Study, a South African birth cohort, were analysed (n=270). Lung function was measured at 6 weeks and 1 year of age, and lower respiratory tract infection episodes were documented. We measured pre- and postnatal PM10 exposures using devices placed in homes, and prenatal tobacco smoke exposure using maternal urine cotinine levels. Genetic risk scores determined from associations with childhood-onset asthma in the UK Biobank were used to investigate effect modifications.ResultsPre- and postnatal exposure to PM10 as well as maternal smoking during pregnancy were associated with reduced lung function at 6 weeks and 1 year as well as with lower respiratory tract infection in the first year. Due to a significant interaction between the genetic risk score and prenatal exposure to PM10, infants carrying more asthma-related risk alleles were more susceptible to PM10-associated reduced lung function (pinteraction=0.007). This interaction was stronger in infants with Black African ancestry (pinteraction=0.001) and nonexistent in children with mixed ancestry (pinteraction=0.876).ConclusionsPM10 and maternal smoking exposures were associated with reduced lung function, with a higher susceptibility for infants with an adverse genetic predisposition for asthma that also depended on the infant's ancestry.


Epidemiology ◽  
2004 ◽  
Vol 15 (4) ◽  
pp. S79-S80
Author(s):  
Tone Smith-Sivertsen ◽  
Nigel Bruce ◽  
Anaite Diaz ◽  
Morten Alexander Schei ◽  
Daniel Pope ◽  
...  

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e9768
Author(s):  
Su-Er Guo ◽  
Miao-Ching Chi ◽  
Chieh-Mo Lin ◽  
Tsung-Ming Yang

Background Among Buddhist or Taoist Taiwanese residents, burning incense is a common source of indoor particulate matter (PM), including PM10 and PM2.5, and can adversely affect the health status of patients with chronic obstructive pulmonary diseases (COPD). However, few studies have focused on the effects of intermittent burning of incense on PM concentration levels and the health status of patients with COPD. This correlational cohort study aimed to investigate the association between burning incense exposure duration, indoor air pollution levels, and lung function in patients with COPD in Taiwan. Methods We assessed 18 outpatients at seven time points with moderate-to-severe COPD using the COPD Assessment Test (CAT), and lung function tests. PM level changes were assessed at seven intervals using generalized estimating equations. Results Participants were primarily male (84%), with a mean age of 72.1 (standard deviation (SD)  ± 9.3) years, and with a mean COPD duration of 3.7 (SD  ± 3.1) years. Both PM10 and PM2.5 levels were the same as the background levels 1 h after incense burning. Burning incense may not influence lung function or symptom severity in patients with COPD in a short-time period. Air quality returned to baseline levels 1 h after burning incense. Conclusion Patients with COPD should avoid staying in rooms where incense is burnt, for up to 1 h. The small sample size and short study period may have influenced our results. Future longitudinal studies with larger sample sizes and long-term follow-ups are recommended.


2021 ◽  
Author(s):  
Jingwei Zhang ◽  
Yuming Wang ◽  
Lihong Feng ◽  
Changchun Hou ◽  
Qing Gu

Abstract Objectives Reduced lung function during childhood could substantially influence the health states of the respiratory system in adults, so, the relationships between air pollution, road proximity, greenspace, indoor air pollution and reduced lung function incidence in children were investigated in this study. Methods The lung function of children was tested every year from 2015 to 2018 and the method of case-control study was applied. Propensity score matching (PSM) was performed to minimize confounding bias and the conditional logistic regression model was carried out to evaluate the effects of indoor and outdoor environmental risk factors on reduced lung function of children. Results Each-one quartile increment in the mixture of the six air pollutants at lag1, lag2 and lag3 periods were related to 46.2%, 9.57% and 8.28% increased risk levels of getting the unhealthy outcome. The protective effect of greenness at lag2 period (Odds ratios (OR) = 0.01 (95% confidence interval (CI): 0–0.02)) was stronger than that at lag1 period (OR = 0.03 (95% CI: 0.01–0.05)). Conclusions Separate and combined effects of most air pollutants at different lag periods represented the hazard effects to the lung function of students. And the distance band of 101–200 m between the home address of each student and the major road could be detrimental to the health of the lung of children significantly. Exposure levels of greenness had protective effects on lung health for students. Only the indoor factor of secondhand smoke exposure was significantly associated with an elevated risk of having reduced lung function.


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