Interleukin 1, interleukin 6 and transforming growth factor-beta production by human gingival mononuclear cells following stimulation with Porphyromonas gingivalis and Fusobacterium nucleatum

1993 ◽  
Vol 28 (2) ◽  
pp. 122-129 ◽  
Author(s):  
E. Gemmell ◽  
G. J. Seymour
Keyword(s):  
Growth Factor ◽  
Porphyromonas Gingivalis ◽  
Transforming Growth Factor Beta ◽  
Interleukin 6 ◽  
Mononuclear Cells ◽  
Transforming Growth Factor ◽  
Interleukin 1 ◽  
Fusobacterium Nucleatum ◽  
Growth Factor Beta

The Expression of IL-1, IL-6, and TGF-β in the Synovial Fluid of Horses with Surgically-Induced Transient Synovitis

1998 ◽  
Vol 11 (03) ◽  
pp. 141-145 ◽  
Author(s):  
S. M. Barber ◽  
J. R. Gordon ◽  
Christine Theoret
Keyword(s):  
Articular Cartilage ◽  
Growth Factor ◽  
Synovial Fluid ◽  
Transforming Growth Factor Beta ◽  
Interleukin 6 ◽  
Transforming Growth Factor ◽  
Interleukin 1 ◽  
Transient Synovitis ◽  
Growth Factor Beta ◽  
Surgically Induced

SummaryThis study investigates the presence of various cytokines in the synovial fluid of three horses with surgicallyinduced synovitis in one antebrachiocarpal joint. Synovial fluids were sampled from experimental and control joints, preoperatively and at two and 30 days post-operatively. Samples were analyzed for interleukin-1 and interleukin- 6 bioactivities with a bioassay, and for transforming growth factor-beta protein by ELISA. Peak cytokine levels were detected on day two post-synovectomy, and returned to pre-operative levels by 30 days post-synovectomy (Interleukin-6 in treated joints: day #0; 0.53 ±0.2, day #2; 9.8 ± 0.7, day #30; 0.4 ± 0.2. Transforming growth factorbeta in treated joints: day #0; 314 ± 69, day #2; 1101 ± 325, day #30; 321 ± 101). Arthrocentesis alone (i.e. control joints) caused no increase in interleukin- 1, interleukin-6 and transforming growth factor-beta levels. Interleukin-1 and interleukin-6 are thought to both prevent anabolic and enhance catabolic effects within articular cartilage matrices, whereas it has been proposed that transforming growth factor-beta may have a protective effect on the articular cartilage. This study is the first to document elevated transforming growth factor-beta levels in equine joints.This study documents elevated levels of transforming growth factor-beta, interleukin-1 and interleukin-6 in the joints of horses with surgically-induced transient synovitis.

Association of interleukin-6 (rs1800796) but not transforming growth factor beta 1 (rs1800469) with serum calcium levels in osteoporotic patients

Gene ◽  
2018 ◽  
Vol 671 ◽  
pp. 21-27 ◽  
Author(s):  
Hajar Eftekhari ◽  
Seyyed Reza Hosseini ◽  
Hadis Pourreza Baboli ◽  
Maryam Mafi Golchin ◽  
Laleh Heidari ◽  
...  
Keyword(s):  
Growth Factor ◽  
Serum Calcium ◽  
Transforming Growth Factor Beta ◽  
Interleukin 6 ◽  
Transforming Growth Factor ◽  
Growth Factor Beta
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