Correlation Between Implant Stability Quotient and Bone-Implant Contact: A Retrospective Histological and Histomorphometrical Study of Seven Titanium Implants Retrieved from Humans

2006 ◽  
Vol 8 (4) ◽  
pp. 218-222 ◽  
Author(s):  
Antonio Scarano ◽  
Marco Degidi ◽  
Giovanna Iezzi ◽  
Giovanna Petrone ◽  
Adriano Piattelli
2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Warwick J. Duncan ◽  
Min-Ho Lee ◽  
Tae-Sung Bae ◽  
Sook-Jeong Lee ◽  
Jennifer Gay ◽  
...  

Spark discharge anodic oxidation forms porous TiO2films on titanium implant surfaces. This increases surface roughness and concentration of calcium and phosphate ions and may enhance early osseointegration. To test this, forty 3.75 mm × 13 mm titanium implants (Megagen, Korea) were placed into healed mandibular postextraction ridges of 10 sheep. There were 10 implants per group: RBM surface (control), RBM + anodised, RBM + anodised + fluoride, and titanium alloy + anodised surface. Resonant frequency analysis (RFA) was measured in implant stability quotient (ISQ) at surgery and at sacrifice after 1-month unloaded healing. Mean bone-implant contact (% BIC) was measured in undemineralised ground sections for the best three consecutive threads. One of 40 implants showed evidence of failure. RFA differed between groups at surgery but not after 1 month. RFA values increased nonsignificantly for all implants after 1 month, except for controls. There was a marked difference in BIC after 1-month healing, with higher values for alloy implants, followed by anodised + fluoride and anodised implants. Anodisation increased early osseointegration of rough-surfaced implants by 50–80%. RFA testing lacked sufficient resolution to detect this improvement. Whether this gain in early bone-implant contact is clinically significant is the subject of future experiments.


2012 ◽  
Vol 38 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Mansour Rismanchian ◽  
Bijan Movahedian Attar ◽  
Sayed Mohammad Razavi ◽  
Ali Nasir Shamsabad ◽  
Majid Rezaei

The endeavors to shorten implant treatment time have led to the concept of immediate loading. This research was designed to compare the immediate loading and the 2-staged methods on implant placement from a clinical, histological, and histomorphometric standpoint. Three months postextraction of 12 premolars of 3 dogs, 12 implants were inserted. Bone-implant contact (BIC), implant stability quotient (ISQ), the bone type in a 2-mm periphery around the implant, and the marginal bone loss (MBL) were recorded for unloaded implants (n  =  6) and immediately loaded ones (n  =  6). BIC, ISQ, MBL in the mesial, and the bone types around the implants were not significantly different in the 2 groups. The distal MBL was higher in the immediately loaded group. Immediate loading does not appear to be perilous for osseointegration, BIC, or new bone type around implants.


2021 ◽  
Author(s):  
Rafael Coutinho Mello-Machado ◽  
Suelen Cristina Sartoretto ◽  
Jose Mauro Granjeiro ◽  
José Albuquerque Calasans-Maia ◽  
Marcelo Jose Guedes Pinheiro Uzeda ◽  
...  

Abstract This study aimed to investigate in vivo the hypothesis that the osseodensification technique, through a wider osteotomy, produce healing chambers at the implant-bone interface with no impact on primary stability osseointegration in low-density bone. Twenty implants (3.5 x 10 mm) presenting nanohydroxyapatite (nHA) surface were inserted in the ilium of ten sheep, after preparation of a 2.7-mm wide implant bed with conventional subtractive drilling (SCD) or a 3.8-mm wide implant bed with an osseodensification bur system (OBS) (n = 5/group/period). The final insertion torque (IT) and implant stability quotient (ISQ) evaluated the primary implant stability. After 14 and 28 days, the bone samples containing the implants were processed for histological and histomorphometric evaluation of bone implant contact (BIC) and bone area fraction occupancy (BAFO). No significant differences occurred between the implant bed preparations regarding IT and ISQ (P > 0.05). Histological analysis showed bone remodeling, and bone growth in all samples with no inflammatory infiltrate. BIC values were higher for SCD after 14 and 28 days (p < 0.05), however BAFO values were similar on both groups (p > 0.05). It was possible to conclude that the osseodensification technique allowed a wider implant bed preparation with no prejudice on primary stability and bone remodeling.


2010 ◽  
Vol 36 (2) ◽  
pp. 97-103 ◽  
Author(s):  
David G. Quintero ◽  
Julia N. Winger ◽  
Rania Khashaba ◽  
James L. Borke

Abstract Advanced glycation endproducts (AGEs) are a diverse group of molecular adducts formed in environments high in reducing sugars that accumulate with aging and in diabetes. This study tests the hypothesis that AGEs inhibit the stabile osseointegration of dental implants through tissue interactions that interfere with bone turnover and compromise the biomechanical properties at the bone-implant interface. Maxillary first molars were extracted from 32 rats and allowed to heal for 4 weeks. Titanium implants (1 mm × 3 mm) were placed in the healed sockets of 2 groups of 16 rats consisting of 8 rats injected 3 times/wk for 1 month with AGE (prepared from glucose and lysine) and 8 rats injected with vehicle as a control. AGE injections continued for an additional 14 or 28 days before sacrifice. X-ray images, blood, and tissues were collected to examine bone/implant contact ratio, serum pyridinoline ([PYD] a collagen breakdown marker), osteocalcin ([OSC] a bone formation marker), and for immunohistochemistry with antibodies to AGE and the bone turnover-marker protein matrix metalloproteinase1. Compared with the AGE-treated groups, the controls showed significantly higher bone/implant contact at both 14- and 28-day time points. PYD (P &lt; .05) and OSC (trend) levels from controls showed decreases at 28 days when compared with AGE-treated groups. Immunohistochemistry with AGE-specific and bone turnover marker antibodies showed stronger staining associated with the implant/tissue interface in AGE-treated rats. Our studies indicate an association between AGE and inhibition of bone turnover, suggesting that the formation of AGE in high glycemic conditions, such as diabetes, may contribute to a slower rate of osseointegration that negatively affects implant stability.


2017 ◽  
Vol 43 (3) ◽  
pp. 186-193 ◽  
Author(s):  
Rosa-María Díaz-Sánchez ◽  
José-María Delgado-Muñoz ◽  
Pilar Hita-Iglesias ◽  
Kyle T. Pullen ◽  
María-Ángeles Serrera-Figallo ◽  
...  

To ensure similar primary implant stability measured by resonance frequency analysis (RFA) could be obtained in different jawbone densities by using a specific surgical drilling protocol and, to correlate those RFA measurements with factors related to the implant design, width, and length, we are performed a 1-year prospective clinical study was carried out using 27 subjects. A total of 67 hydrophilic titanium implants were placed using a standard 2-stage implant placement protocol. The bone type at each implant site was determined by evaluation of a preoperative, high-resolution cone beam computerized tomography (CBCT) scan. A modified drilling protocol was used in softer bone (types 2, 3, and 4) that allowed for greater implant thread contact with the surrounding bone. The implant stability quotient (ISQ) was measured at 4 different times during the study: initially it was determined immediately after implant placement, then again at stage 2 uncovering surgery, then at 6 months' postplacement and, and finally at 1 year postplacement. Data collected immediately after implant surgery demonstrated a high correlation (R2 = .99) between the ISQ and bone type classification. An overall trend toward a higher ISQ was found over the 1-year study period for all types of bone. Implants remained clinically and radiographically stable during the 1-year study period. Our data allow conclude that the primary stability of 2-staged loaded implants placed in different bone types can be optimized by applying this surgical drilling protocol during the implant placement. The ISQ method was found to be a reliable predictor of implant stability.


2015 ◽  
Vol 42 (3) ◽  
pp. 302-310 ◽  
Author(s):  
Henning Schliephake ◽  
Jennifer Rublack ◽  
Anne Förster ◽  
Bernd Schwenzer ◽  
Judith Reichert ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-10
Author(s):  
Hsiang-Ho Chen ◽  
Wei-Yi Lai ◽  
Tze-Jian Chee ◽  
Ya-Hui Chan ◽  
Sheng-Wei Feng

The aim of this study was to monitor the changes of viscoelastic properties at bone-implant interface via resonance frequency analysis (RFA) and the Periotest device during the healing process in an experimental rabbit model. Twenty-four dental implants were inserted into the femoral condyles of rabbits. The animals were sacrificed immediately after implant installation or on day 14, 28, or 56 after surgery. Viscoelastic properties at bone-implant interface were evaluated by measuring the implant stability quotient (ISQ) using RFA and by measuring the Periotest values (PTVs) using the Periotest device. The bone/implant specimens were evaluated histopathologically and histomorphometrically to determine the degree of osseointegration (BIC%). The BIC% values at different time points were then compared with the corresponding ISQ values and PTVs. The mean ISQ value increased gradually and reached 81±1.7 on day 56, whereas the mean PTV decreased over time, finally reaching −0.7±0.5 on day 56. Significant correlations were found between ISQ and BIC% (r=0.701, p<0.001), PTV and BIC% (r=-0.637, p<0.05), and ISQ and PTV (r=-0.68, p<0.05). These results show that there is a positive correlation between implant stability parameters and peri-implant-bone healing, indicating that the RFA and Periotest are useful for measuring changes of viscoelastic properties at bone-implant interface and are reliable for indirectly predicting the degree of osseointegration.


2013 ◽  
Vol 39 (5) ◽  
pp. 583-590 ◽  
Author(s):  
Moustafa N. Aboushelib ◽  
Noha A. Salem ◽  
Ahmed L. Abo Taleb ◽  
Naglaa M. Abd El Moniem

This study evaluates osseous healing of selective infiltration-etched (SIE) zirconia implants compared to as-sintered zirconia and titanium implants. Twenty implants of each group were inserted in 40 adult New Zealand white male rabbits. After 4 and 6 weeks, bone blocks containing the implants were retrieved, sectioned, and processed to evaluate bone-implant contact (BIC) and peri-implant bone density. SIE zirconia implants had significantly higher BIC and marginally higher bone density. The results suggest that selective infiltration-etched zirconia implant surface may improve implant osseointegration.


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