Validation of a new point-of-care assay for determination of β-carotene concentration in bovine whole blood and plasma

2012 ◽  
pp. n/a-n/a ◽  
Author(s):  
Jens Raila ◽  
Francis Enjalbert ◽  
Ralf Mothes ◽  
Andrea Hurtienne ◽  
Florian J. Schweigert
The Analyst ◽  
2018 ◽  
Vol 143 (18) ◽  
pp. 4422-4428 ◽  
Author(s):  
Jin Huang ◽  
Xue-Li Zhu ◽  
Yu-Min Wang ◽  
Jian-Hui Ge ◽  
Jin-Wen Liu ◽  
...  

In this work, a versatile point-of-care assay platform based on a microfluidic paper-based analytic device (μPAD) was developed for the simultaneous detection of multiple targets.


2003 ◽  
Vol 332 (1-2) ◽  
pp. 51-59 ◽  
Author(s):  
Jae Soon Ahn ◽  
Sunga Choi ◽  
Sang Ho Jang ◽  
Hyuk Jae Chang ◽  
Jae Hoon Kim ◽  
...  

Author(s):  
Mario A. Inchiosa ◽  
Suryanarayana Pothula ◽  
Keshar Kubal ◽  
Vajubhai T. Sanchala ◽  
Iris Navarro

Author(s):  
Alexander Kutz ◽  
Pierre Hausfater ◽  
Michael Oppert ◽  
Murat Alan ◽  
Eva Grolimund ◽  
...  

AbstractProcalcitonin (PCT) is increasingly being used for the diagnostic and prognostic work up of patients with suspected infections in the emergency department (ED). Recently, B·R·A·H·M·S PCT direct, the first high sensitive point-of-care test (POCT), has been developed for fast PCT measurement on capillary or venous blood samples.This is a prospective, international comparison study conducted in three European EDs. Consecutive patients with suspicion of bacterial infection were included. Duplicate determination of PCT was performed in capillary (fingertip) and venous whole blood (EDTA), and compared to the reference method. The diagnostic accuracy was evaluated by correlation and concordance analyses.Three hundred and three patients were included over a 6-month period (60.4% male, median age 65.2 years). The correlation between capillary or venous whole blood and the reference method was excellent: rThis study found a high diagnostic accuracy and a faster time to result of B·R·A·H·M·S PCT direct in the ED setting, allowing shortening time to therapy and a more wide-spread use of PCT.


2011 ◽  
Vol 32 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Mario A. Inchiosa ◽  
Suryanarayana Pothula ◽  
Keshar Kubal ◽  
Vajubhai T. Sanchala ◽  
Iris Navarro

Author(s):  
Evangelos Giannitsis ◽  
Hannsjörg Baum ◽  
Thomas Bertsch ◽  
Martin Juchum ◽  
Margit Müller-Bardorff ◽  
...  

2007 ◽  
Vol 14 (5 Supplement 1) ◽  
pp. S185-S185
Author(s):  
M. Leonard ◽  
A. Jones ◽  
J. Hernandez-Nino ◽  
J. Kline
Keyword(s):  

2017 ◽  
Vol 2 (7) ◽  
pp. 514-520 ◽  
Author(s):  
Jason Grebely ◽  
Francois M J Lamoury ◽  
Behzad Hajarizadeh ◽  
Yasmin Mowat ◽  
Alison D Marshall ◽  
...  

Author(s):  
Gary Brook ◽  
Tetiana Stepchenkova ◽  
Innocent M. Ali ◽  
Sandra Chipuka ◽  
Neha Goel ◽  
...  

Remote areas of many low and middle income (LMI) countries have poor access to HIV viral load (HIV VL) testing. The SAMBA-II (Simple Amplification-based Assay) Semi-Q Whole Blood Test (Diagnostics for the Real World (DRW), Cambridge, UK) is a point of care assay which uses leucodepletion technology to allow whole blood testing in remote settings. 1540 consecutive HIV-positive clinic patients in Cameroon (250), UK (633), Ukraine (412) and Zimbabwe (245) donated venous blood (all countries) and finger-prick blood (all except UK) for testing on SAMBA-II. SAMBA II results were compared with simultaneous plasma results on the Abbott RealTime HIV-1 (Abbott Molecular, Des Plaines, IL) viral load assay and interpreted as either <1000 RNA copies/ml or ≥1000 RNA copies/ml. For 1528 venous whole-blood samples tested on SAMBA II, overall percent agreement with the reference test at a cut-off of HIV VL ≥1000 cps/ml was 96.9% (1480/1528 95% CI 95.9-97.7), negative percent agreement 97.7% (1259/1289 95% CI 96.7-98.4), positive percent agreement 92.5% (221/239 95% CI 88.4-95.5). For 854 finger-prick samples there was 95.0% (811/854 95% CI 93.3-96.3) overall percent agreement; negative percent agreement 98.0% (625/638, 95% CI 96.5-98.9); positive percent agreement 86.1% (186/216 95% CI 80.8-90.4). These rose to 93.5% (82.1, 98.6), 97.6% (95.6, 98.8) and 95.6% (93.3, 97.3) after exclusion of aberrant results from the Ukraine centre. These results show a high level of agreement between SAMBA-II and a laboratory-based assay. SAMBA-II has a performance that is suitable to use as a VL point of care assay in remote settings


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