Patient Acceptance: Metrics, Meaning, and the “Missing Piece” in Evaluating Novel Devices

2021 ◽  
Author(s):  
Samuel F. Sears ◽  
Zachary Force ◽  
Saleen Khan ◽  
Rajasekhar Nekkanti
Keyword(s):  
Patient Acceptance ◽  
Novel Devices

Novel Devices for the Shop and the Home

1926 ◽  
Vol 134 (3) ◽  
pp. 182-184
Author(s):  
Albert A. Hopkins
Keyword(s):  
Novel Devices

Sex Differences in Patient Acceptance of Cardiac Transplant Candidacy

Circulation ◽  
1995 ◽  
Vol 91 (11) ◽  
pp. 2753-2761 ◽  
Author(s):  
Keith D. Aaronson ◽  
J. Sanford Schwartz ◽  
James E. Goin ◽  
Donna M. Mancini
Keyword(s):  
Sex Differences ◽  
Patient Acceptance ◽  
Cardiac Transplant

Dialysis today: Methods, technologies and strategies

1980 ◽  
Vol 3 (3) ◽  
pp. 153-156 ◽  
Author(s):  
A. Vercellone ◽  
G.P. Segoloni ◽  
G. Triolo ◽  
C. Canavese ◽  
M. Messina
Keyword(s):  
Patient Acceptance ◽  
Open Policy

Dialysis is a method of treatment which in over 30 years of progress has developed different technologies and strategies now to be unified in a single dialytic culture. In our experience we have decided to adopt an open policy as for the patient acceptance and the setting of modes of therapy, taking in account 5 fundamental criteria: i.e. dialytic adequacy, rehabilitation, safety, economy and working simplicity. Today short dialysis is the backbone schedule we have developed with an intensive participation of the patients to their treatment. Yet our results are not only the expression of a schedule but also a demonstration of how valuable may result some cautions in the management of the RDT patient.

scholarly journals Design of Mucoadhesive Strips for Buccal Fast Release of Tramadol

Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1187
Author(s):  
Nayla Francine Garcia Pastório ◽  
Camila Felix Vecchi ◽  
Rafaela Said dos Santos ◽  
Marcos Luciano Bruschi
Keyword(s):  
Ex Vivo ◽  
Polymer Concentration ◽  
Peroral Administration ◽  
Patient Acceptance ◽  
Poly Vinyl Alcohol ◽  
Synthetic Analogue ◽  
Drug Release Profile ◽  
Opioid Agonist ◽  
In Vivo Evaluation ◽  
Tramadol Hydrochloride

Tramadol hydrochloride is a synthetic analogue of codeine and shows activity on the central nervous system as an opioid agonist and inhibitor of serotonin and norepinephrine reuptake. It has been used for controlling moderate to severe pain. Mucoadhesive fast-dissolving films can present greater drug availability and patient acceptance when compared to the systems of peroral administration. The films were prepared using the solvent casting method with ethylcellulose, polyvinylpyrrolidone and poly(vinyl alcohol). The effect of each polymer concentration was investigated using a 2³ factorial design with repetition at the central point. The formulations were subjected to physicochemical, mechanical, ex vivo mucoadhesive and in vitro drug release profile analysis. These properties were dependent on the polymeric composition (independent factors) of each system. The optimized formulations showed good macroscopic characteristics, improved resistance to bending, rigidity, rapid swelling up to 60 s, improved mechanical and mucoadhesive characteristics, and also fast dissolving and tramadol release. The optimized formulations constitute platforms and strategies to improve the therapy of tramadol with regard to availability at the site of application, considering the necessity of rapid pain relief, and show potential for in vivo evaluation.

scholarly journals The Perioperative System: A New Approach to Managing Elective Surgery

1995 ◽  
Vol 23 (5) ◽  
pp. 591-596 ◽  
Author(s):  
R. Kerridge ◽  
A. Lee ◽  
E. Latchford ◽  
S. J. Beehan ◽  
K. M. Hillman
Keyword(s):  
Hospital Discharge ◽  
Elective Surgery ◽  
Average Length ◽  
University Teaching ◽  
Patient Acceptance ◽  
Discharge Process ◽  
Average Length Of Stay ◽  
Elective Surgical Procedures ◽  
Surgery Patient ◽  
Day Of Surgery Admission

A Perioperative Service has recently been introduced at Liverpool Hospital, a 460-bed university teaching hospital. This provides a co-ordinated system for managing all elective surgical patients from the time an admission is booked until hospital discharge. This paper describes the patient assessment, structure and staff requirements, benefits of and problems encountered with this service. The patient's preoperative preparation occurs before hospital admission. Where possible, patients are admitted on the day of procedure, either as a day-only patient, or a day-of-surgery patient. Patients are initially admitted to a specifically designed Perioperative Unit, adjacent to the Operating Theatre Suite. Patients do not enter the surgical wards until after their operation. Planning of the hospital discharge process commences at the time of booking for operation. Introduction of the Perioperative Service was staged process commencing in mid-1992. The hospital admits approximately 6,400 elective surgery cases each year. From July 1992 to December 1994, day-only patients were approximately 45% of these cases. Day-of-surgery admission patients increased from 6% to 35% of all cases over the same period. Appproximately 22% of elective surgical cases were seen in the Perioperative Clinic. As the Perioerative Service became fully operational, the average length of stay for elective surgical procedures fell. There has been a reduction in the areas of cancellations due to unavailablity of beds, inappropriate preparation of patients, and non-attendance of patients for booked procedures. Patient acceptance is high. The existence of a perioperative system facilitates the planning and management of elective surgery with maximum quality and efficiency.

scholarly journals Prevalence and Determinants of Vaccine Hesitancy and Vaccines Recommendation Discrepancies among General Practitioners in French-Speaking Parts of Belgium

Vaccines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 771
Author(s):  
Cathy Gobert ◽  
Pascal Semaille ◽  
Thierry Van der Schueren ◽  
Pierre Verger ◽  
Nicolas Dauby
Keyword(s):  
General Practitioners ◽  
Online Survey ◽  
Critical Role ◽  
Personal Characteristics ◽  
Vaccine Hesitancy ◽  
Patient Acceptance ◽  
Recent Experience ◽  
Average Percentage ◽  
Vaccine Recommendations ◽  
Increased Risk

General practitioners (GPs) play a critical role in patient acceptance of vaccination. Vaccine hesitancy (VH) is a growing phenomenon in the general population but also affects GPs. Few data exist on VH among GPs. The objectives of this analysis of a population of GPs in the Belgian Wallonia-Brussels Federation (WBF) were to: (1) determine the prevalence and the features of VH, (2) identify the correlates, and (3) estimate the discrepancy in vaccination’s behaviors between the GPs’ children and the recommendations made to their patients. An online survey was carried out among the population of general practitioners practicing in the WBF between 7 January and 18 March 2020. A hierarchical cluster analysis was carried out based on various dimensions of vaccine hesitancy: perception of the risks and the usefulness of vaccines as well as vaccine recommendations for their patients. A total of 251 GPs answered the survey. The average percentage of moderate to high vaccine hesitancy was 50.6%. Three factors were independently associated with increased risk of vaccine hesitancy: an age <50 years old, having no children, and having no contact with selected vaccine-preventable disease (measles, complicated influenza, chronic hepatitis B (HBV), bacterial meningitis, or cervical cancer) in the past 5 years. VH was associated with controversies on vaccines’ safety. GPs who had vaccinated their children against six diseases (MMR, meningococcus C (MenC), HBV, and HPV) tended not to recommend the same vaccines to their patients. Among GPs with all children vaccinated against HBV, only 37.5% recommended catch-up HBV immunization to their patients. In this small cohort of GP, moderate to high VH was associated with controversies on vaccines’ safety and with specific personal characteristics (age <50, no children, and no recent experience with a serious VPD). As previously reported, GPs have different vaccine prescription attitude toward their patients and children. These findings should be confirmed in larger cohorts.

Semiconductors at IBM: Physics, Novel Devices, and Materials Science

1981 ◽  
Vol 25 (5) ◽  
pp. 779-792 ◽  
Author(s):  
R. W. Keyes ◽  
M. I. Nathan
Keyword(s):  
Materials Science ◽  
Novel Devices

EUROPEAN PAEDIATRIC ONCOLOGY OFF-PATENT MEDICINES CONSORTIUM (EPOC): A PHARMACOKINETIC STUDY OF DOXORUBICIN IN CHILDREN WITH CANCER

2015 ◽  
Vol 101 (1) ◽  
pp. e1.6-e1
Author(s):  
Miriam Krischke ◽  
Alan V Boddy ◽  
Georg Hempel ◽  
Swantje Völler ◽  
Nicolas André ◽  
...  
Keyword(s):  
Pharmacokinetic Study ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Paediatric Oncology ◽  
Patient Acceptance ◽  
Pharmacokinetic Parameters ◽  
Blood Levels ◽  
Population Pharmacokinetic ◽  
Older Children ◽  
Treatment Regimens

BackgroundDoxorubicin is a key component of a number of treatment regimens used in paediatric oncology. The pharmacology data on which current dosing regimens are based are very limited.MethodsWe conducted a multicentre, multinational pharmacokinetic study investigating age-dependency in the clearance of doxorubicin in children with solid tumours and leukaemia. Blood samples for measurement of doxorubicin and its metabolite doxorubicinol were collected after 2 administrations, with 5 samples collected in children 3 yrs. A population pharmacokinetic approach was used for analysis, including pharmacogenetic covariates. NT-proBNP and cardiac troponin T were measured to evaluate their role as early indicators of cardiotoxicity.Results101 children could be recruited including 27 patients less than 3 years and among those 5 infants younger than 1 year. Overall, the patient acceptance of the trial was very good.Age dependence of doxorubicin clearance was demonstrated, with children less than 3 years having a lower clearance (21.1±5.8 l/h/m2) than older children (26.6±6.7 l/h/m2) (p=0.0004), after correcting for body weight. Pharmacogenetic variants, including those in transporters and drug metabolizing enzymes, had little influence on pharmacokinetic parameters.Natriuretic peptides plasma levels increased significantly shortly after doxorubicin administration, whereas cardiac troponin levels increased only with the administered cumulative anthracycline dose. Only limited correlation could be observed between their blood levels and doxorubicin pharmacokinetics.ConclusionThe paediatric need concerning missing PK-data could be addressed with limited burden for the patients. Empirically used dose adaptations for infants were found to be justified based on our PK analyses.

scholarly journals Alveolar ridge dimensional changes following ridge preservation procedure with novel devices: Part 1 – CBCT linear analysis in non‐human primate model

2015 ◽  
Vol 27 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Seiko Min ◽  
Yi Liu ◽  
Jianxia Tang ◽  
Yilin Xie ◽  
Jimin Xiong ◽  
...  
Keyword(s):  
Linear Analysis ◽  
Ridge Preservation ◽  
Alveolar Ridge ◽  
Primate Model ◽  
Dimensional Changes ◽  
Novel Devices ◽  
Human Primate
Sign in / Sign up

Export Citation Format

Share Document