scholarly journals Association between remnant cholesterol and arterial stiffness: A secondary analysis based on a cross‐sectional study

2021 ◽  
Author(s):  
Zhenwei Wang ◽  
Min Li ◽  
Jing Xie ◽  
Jing Gong ◽  
Naifeng Liu
Keyword(s):  
Arterial Stiffness ◽  
Secondary Analysis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Remnant Cholesterol

scholarly journals AST to ALT ratio and arterial stiffness in non-fatty liver Japanese population:a secondary analysis based on a cross-sectional study

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Yongmei Liu ◽  
Peiling Zhao ◽  
Mingliang Cheng ◽  
Lei Yu ◽  
Zhuo Cheng ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Fatty Liver ◽  
Secondary Analysis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals The relationship between the atherogenic index of plasma and arterial stiffness in essential hypertensive patients from China: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Juan Yin ◽  
Minghui Li ◽  
Lingling Yu ◽  
Feng Hu ◽  
Yu Yu ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Arterial Stiffness ◽  
Linear Regression Analysis ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Chinese Patients ◽  
Multivariate Linear Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma

Abstract Background The atherogenic index of plasma (AIP) always remains in a potential association with arterial stiffness, however, this association has not been fully discovered and needs to be studied in depth in large hypertensive patient populations. The present analysis thus sought to further explore the association that exists between AIP and arterial stiffness in Chinese patients diagnosed with arterial hypertension. Methods This cross-sectional study analyzed 4744 Chinese individuals with essential hypertension. AIP was defined as the base 10 logarithm of the ratio of plasma of triglycerides to high-density lipoprotein cholesterol levels indicated in molar concentrations. Measurement of arterial stiffness was carried out via brachial-ankle pulse wave velocity (baPWV). Results Data were adjusted for potential confounding variables, and multivariate linear regression analysis revealed AIP to be positively correlated with baPWV (β = 1.34, 95% CI: 0.96 to 1.72, P < 0.001). When AIP was instead treated as a categorical variable divided into quartiles, the same relationship was observed (P for trend < 0.001). We additionally found AIP and baPWV had a stronger positive association in individuals with a body mass index (BMI) < 24 kg/m2 (P for interaction < 0.05). Conclusion AIP and arterial stiffness were positively correlated in essential hypertension patients in China, especially in those with a BMI < 24 kg/m2. Clinical trial registration ChiCTR1800017274.

scholarly journals Radiation effects on atherosclerosis in atomic bomb survivors: a cross‐sectional study using structural equation modeling

2021 ◽  
Vol 36 (4) ◽  
pp. 401-414
Author(s):  
Tomoki Nakamizo ◽  
John Cologne ◽  
Kismet Cordova ◽  
Michiko Yamada ◽  
Tetsuya Takahashi ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Radiation Exposure ◽  
Structural Equation ◽  
Atomic Bomb ◽  
Cross Sectional Study ◽  
Equation Modeling ◽  
Study Cohort ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atomic Bomb Survivors

AbstractPast reports indicated that total-body irradiation at low to moderate doses could be responsible for cardiovascular disease risks, but the mechanism remains unclear. The purpose of this study was to investigate the association between radiation exposure and atherosclerosis, an underlying pathology of cardiovascular diseases, in the Japanese atomic bomb survivors. We performed a cross-sectional study measuring 14 clinical-physiological atherosclerosis indicators during clinical exams from 2010 to 2014 in 3274 participants of the Adult Health Study cohort. Multivariable analyses were performed by using a structural equation model with latent factors representing underlying atherosclerotic pathologies: (1) arterial stiffness, (2) calcification, and (3) plaque　as measured with indicators chosen a priori on the basis of clinical-physiological knowledge. Radiation was linearly associated with calcification (standardized coefficient per Gy 0.15, 95 % confidence interval: CI [0.070, 0.23]) and plaque (0.11, 95 % CI [0.029, 0.20]), small associations that were comparable to about 2 years of aging per Gy of radiation exposure, but not with arterial stiffness (0.036, 95 % CI [− 0.025, 0.095]). The model fitted better and had narrower confidence intervals than separate ordinary regression models explaining individual indicators independently. The associations were less evident when the dose range was restricted to a maximum of 2 or 1 Gy. By combining individual clinical-physiological indicators that are correlated because of common, underlying atherosclerotic pathologies, we found a small, but significant association of radiation with atherosclerosis.

scholarly journals The Relationship Between the Atherogenic Index of Plasma and Arterial Stiffness in Essential Hypertensive Patients from China: A Cross-Sectional Study

2021 ◽  
Author(s):  
Juan Yin ◽  
Minghui Li ◽  
Lingling Yu ◽  
Feng Hu ◽  
Yu Yu ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Arterial Stiffness ◽  
Linear Regression Analysis ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Multivariate Linear Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma

Abstract Background: The atherogenic index of plasma (AIP) always remains in a potential association with the arterial stiffness, however, in large hypertensive patient populations, this relation is not fully discovered and needs to be studied in depth. The present analysis thus sought to further explore the association that exists between AIP and arterial stiffness in patients diagnosed with arterial hypertension in China.Methods: This cross-sectional study analyzed 4744 Chinese individuals with essential hypertension. AIP was defined as the base 10 logarithm of the ratio of plasma of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-c) levels indicates as in molar concentrations. Measurement of arterial stiffness was carried out via brachial-ankle pulse wave velocity (baPWV).Results: Data were adjusted for potential confounding variables, after which a multivariate linear regression analysis revealed AIP to be positively correlated with baPWV (β = 1.34, 95% CI: 0.96 to 1.72, P < 0.001). When AIP was instead treated as a categorical variable divided into quartiles, this same relationship was observed (P for trend < 0.001). We additionally found AIP and baPWV had a stronger positive association in individuals with a body mass index (BMI) < 24 kg/m2 (P for interaction < 0.05).Conclusion: AIP and arterial stiffness were positively correlated in essential hypertension patients in China, especially in those with a BMI < 24 kg/m2.

scholarly journals Oxidative Stress is Closely Associated with Increased Arterial Stiffness, Especially in Aged Male Smokers without Previous Cardiovascular Events: A Cross-Sectional Study

2017 ◽  
Vol 24 (11) ◽  
pp. 1186-1198 ◽  
Author(s):  
Tomonori Sugiura ◽  
Yasuaki Dohi ◽  
Hiroyuki Takase ◽  
Sumiyo Yamashita ◽  
Satoshi Fujii ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Arterial Stiffness ◽  
Cardiovascular Events ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Mental capacity assessment: a descriptive, cross-sectional study of what doctors think, know and do

2020 ◽  
pp. medethics-2019-105819
Author(s):  
Dexter Penn ◽  
Anne Lanceley ◽  
Aviva Petrie ◽  
Jacqueline Nicholls
Keyword(s):  
Best Practice ◽  
Secondary Analysis ◽  
Cross Sectional Study ◽  
Mental Capacity ◽  
Capacity Assessment ◽  
Career Stage ◽  
Sectional Study ◽  
Cross Sectional ◽  
Self Confidence ◽  
Mental Capacity Act

BackgroundThe Mental Capacity Act (MCA) (2005) was enacted in 2007 in England and Wales, but the assessment of mental capacity still remains an area of professional concern. Doctors’ compliance with legal and professional standards is inconsistent, but the reasons for poor compliance are not well understood. This preliminary study investigates doctors’ experiences of and attitudes toward mental capacity assessment (MCAx).MethodsThis is a descriptive, cross-sectional study where a two-domain, study-specific structured questionnaire was developed, piloted and digitally disseminated to doctors at differing career stages employed in a large, multi-site National Health Service Trust in London over 4 months in 2018. Descriptive statistics and frequency tables adjusted for missing data were generated and secondary analysis was conducted.ResultsParticipants (n=92) were predominantly UK trained (82%), female (58%) and between the ages of 30 and 44 years (45%). Less than half (45%) of the participants reported receiving formal MCAx training. Only one-third (32%) of the participants self-rated themselves as very competent (29%) or extremely competent (4%). Self-reported MCA confidence was significantly affected by career stage with Consultants with over 10 years of experience reporting lowest confidence (p=0.001).ConclusionsThis study describes significant variation in practice by doctors and low self-confidence in the practice of MCAx. These results raise concerns that MCAx continues to be inconsistently performed by doctors despite appropriate awareness of the law and professional guidance on best practice.

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