scholarly journals The role of maternal anxiety disorder subtype, parenting and infant stable temperamental inhibition in child anxiety: a prospective longitudinal study

2020 ◽  
Vol 61 (7) ◽  
pp. 779-788
Author(s):  
Peter J. Lawrence ◽  
Cathy Creswell ◽  
Peter J. Cooper ◽  
Lynne Murray
Keyword(s):  
Longitudinal Study ◽  
Anxiety Disorder ◽  
Child Anxiety ◽  
Maternal Anxiety ◽  
Prospective Longitudinal Study ◽  
Prospective Longitudinal

Maternal anxiety disorders prior to conception, psychopathology during pregnancy and early infants’ development: a prospective-longitudinal study

2013 ◽  
Vol 16 (6) ◽  
pp. 549-560 ◽  
Author(s):  
Julia Martini ◽  
Julia Wittich ◽  
Johanna Petzoldt ◽  
Susanne Winkel ◽  
Franziska Einsle ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Anxiety Disorders ◽  
Maternal Anxiety ◽  
Prospective Longitudinal Study ◽  
Prospective Longitudinal

scholarly journals The Association of Serum Levels of Brain-Derived Neurotrophic Factor with the Occurrence of and Recovery from Delirium in Older Medical Inpatients

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
John Williams ◽  
Karen Finn ◽  
Vincent Melvin ◽  
David Meagher ◽  
Geraldine McCarthy ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Generalized Estimating Equations ◽  
Serum Levels ◽  
Apache Ii ◽  
Elisa Method ◽  
Prospective Longitudinal Study ◽  
Medical Inpatients ◽  
Prospective Longitudinal ◽  
The Relationship

Limited studies of the association between BDNF levels and delirium have given inconclusive results. This prospective, longitudinal study examined the relationship between BDNF levels and the occurrence of and recovery from delirium. Participants were assessed twice weekly using MoCA, DRS-R98, and APACHE II scales. BDNF levels were estimated using an ELISA method. Delirium was defined with DRS-R98 (score > 16) and recovery from delirium as ≥2 consecutive assessments without delirium prior to discharge. We identified no difference in BDNF levels between those with and without delirium. Excluding those who never developed delirium (n=140), we examined the association of BDNF levels and other variables with delirium recovery. Of 58 who experienced delirium, 39 remained delirious while 19 recovered. Using Generalized Estimating Equations models we found that BDNF levels (Wald χ2=7.155; df: 1, p=0.007) and MoCA (Wald χ2=4.933; df: 1, p=0.026) were associated with recovery. No significant association was found for APACHE II, dementia, age, or gender. BDNF levels do not appear to be directly linked to the occurrence of delirium but recovery was less likely in those with continuously lower levels. No previous study has investigated the role of BDNF in delirium recovery and these findings warrant replication in other populations.

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