High concentration of oxaliplatin may be a risk factor for vascular pain

Author(s):  
Satoru Matsunuma ◽  
Satoko Handa ◽  
Hitomi Yamamoto ◽  
Kiyoshi Okuyama ◽  
Koichi Yoshimoto ◽  
...  
Diabetologia ◽  
1995 ◽  
Vol 38 (10) ◽  
pp. 1213-1217 ◽  
Author(s):  
G. Paolisso ◽  
P. A. Tataranni ◽  
J. E. Foley ◽  
C. Bogardus ◽  
B. V. Howard ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Claudia Iveth Mendoza-López ◽  
Javier Del-Angel-Caraza ◽  
María Alejandra Aké-Chiñas ◽  
Israel Alejandro Quijano-Hernández ◽  
Jody P. Lulich ◽  
...  

Silica urolithiasis is infrequent in dogs, but in Mexico represents 12.9%. Our hypothesis is the consumption of high amounts of silicates in the diet, especially that dissolved in tap water. The objective of this study was to determine the concentrations of silica in the tap water in different geographical areas and their relationship with cases of silicate urolithiasis in dogs. From 179 cases of silicate urolithiasis, 98.9% were from dogs within a geographic area called the Trans-Mexican Volcanic Belt, which represents a cross shaft to the center of the country. Silica concentrations in tap water ranged between 3 and 76 mg/L, with a range of 27 to 76 mg/L, a mean of 49.9 ± 12 mg/L within the Trans-Mexican Volcanic Belt, and a concentration from 3 to 30 mg/L, with a mean of 16.4 ± 7 mg/L outside this area; these were significantly different ( p < 0.001 ). These findings demonstrate that there is a geographic risk factor for silicate urolithiasis in urolith-forming dogs, related to the consumption of tap water with a high concentration of silica. Further studies are necessary to identify this same pathophysiological association in other species.


2003 ◽  
Vol 331 (1-2) ◽  
pp. 25-28 ◽  
Author(s):  
Taner Ozgurtas ◽  
Cemil Yildiz ◽  
Muhittin Serdar ◽  
Sabri Atesalp ◽  
Turker Kutluay

Diabetologia ◽  
1995 ◽  
Vol 38 (10) ◽  
pp. 1213-1217 ◽  
Author(s):  
G. Paolisso ◽  
P. A. Tataranni ◽  
J. E. Foley ◽  
C. Bogardus ◽  
B. V. Howard ◽  
...  

Author(s):  
Yukio Suga ◽  
Yuriya Sakaguchi ◽  
Junko Ishizaki ◽  
Makiko Takabayashi ◽  
Chiaki Hashimoto ◽  
...  

Author(s):  
Olufemi Olamide Ajumobi ◽  
Ahmed Tsofo ◽  
Matthias Yango ◽  
Mabel Kamweli Aworh ◽  
Ifeoma Nkiruka Anagbogu ◽  
...  

1996 ◽  
Vol 11 (4) ◽  
pp. 207-210 ◽  
Author(s):  
G. Banfi ◽  
A. Ardemagni ◽  
S. Bravi ◽  
M. Pacchioni ◽  
P. Bonini

Diabetes has been claimed to be a risk factor for pancreatic carcinoma, but it is probably a consequence of gland invasion from the neoplastic tissue. A link between diabetes and pancreatic carcinoma was suggested by means of biochemical markers of the diseases, namely glycated hemoglobin and CA19.9. Moreover, CA19.9 was proposed as a sensitive and useful marker of the severity of exocrine damage in diabetes, since the mucin decreased when metabolic compensation improved. We examined 64 diabetic patients (36 insulin dependent, 16 non insulin dependent, 12 treated with diet) by measuring CA19.9 using two different immunometric methods and glycemia and glycated hemoglobin. We observed that a correlation between CA19.9 and biochemical markers of metabolic compensation of diabetes was inexistent and no differences between insulin dependent and non insulin dependent patients were found. A high concentration of CA19.9 in a diabetic patient should be interpreted and evaluated in the same manner as for a non diabetic patient.


Author(s):  
Daniel C. Pease

A previous study demonstrated that tissue could be successfully infiltrated with 50% glutaraldehyde, and then subsequently polymerized with urea to create an embedment which retained cytomembrane lipids in sectioned material. As a result, the 180-190 Å periodicity characteristic of fresh, mammalian myelin was preserved in sections, as was a brilliant birefringence, and the capacity to bind OsO4 vapor in the hydrophobic bilayers. An associated (unpublished) study, carried out in co-operation with Drs. C.K. Akers and D.F. Parsons, demonstrated that the high concentration of glutaraldehyde (and urea) did not significantly alter the X-ray diffraction pattern of aldehyde-fixed, myelin. Thus, by itself, 50% glutaraldehyde has little effect upon cytomembrane systems and can be used with confidence for the first stages of dehydration.


Author(s):  
Glenn M. Cohen ◽  
Radharaman Ray

Retinal,cell aggregates develop in culture in a pattern similar to the in ovo retina, forming neurites first and then synapses. In the present study, we continuously exposed chick retinal cell aggregates to a high concentration (1 mM) of carbamylcholine (carbachol), an acetylcholine (ACh) analog that resists hydrolysis by acetylcholinesterase (AChE). This situation is similar to organophosphorus anticholinesterase poisoning in which the ACh level is elevated at synaptic junctions due to inhibition of AChE, Our objective was to determine whether continuous carbachol exposure either damaged cholino- ceptive neurites, cell bodies, and synaptic elements of the aggregates or influenced (hastened or retarded) their development.The retinal tissue was isolated aseptically from 11 day embryonic White Leghorn chicks and then enzymatically (trypsin) and mechanically (trituration) dissociated into single cells. After washing the cells by repeated suspension and low (about 200 x G) centrifugation twice, aggregate cell cultures (about l0 cells/culture) were initiated in 1.5 ml medium (BME, GIBCO) in 35 mm sterile culture dishes and maintained as experimental (containing 10-3 M carbachol) and control specimens.


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