Optimization of ultrasound‐assisted ethanol extraction of hazelnut oil

2019 ◽  
Vol 43 (10) ◽  
Author(s):  
Shi Ting Wong ◽  
Mei Ching Tan ◽  
Chin Hong Geow
Author(s):  
Cleidijane dos Santos ◽  
Carlos Padilha ◽  
Karla Damasceno ◽  
Pedro Leite ◽  
Ana de Araújo ◽  
...  

The present study investigated the use of choline chloride:glycerol deep eutectic solvent as an adjuvant for tuning the ethanol extraction of astaxanthin from Litopenaeus vannamei processing residues. The adjuvant concentration did not show a clear trend on the total carotenoid, however, the addition of adjuvant proved to be advantageous in the ultrasound-assisted experiments. In order to establish a balance between total carotenoid and productivity, an operational condition with ultrasound, 5% (m/v) choline chloride:glycerol and 10 min of incubation was selected, which provided 737.69 μg g-1 total carotenoids and 32.71 μg g-1 astaxanthin. When compared to the astaxanthin standard, the shrimp residue extract obtained greater antioxidant activity in free radical scavenging tests. In addition, the shrimp residue extract dramatically reduced the dosage of norfloxacin (up to 87.5%) and gentamicin (up to 75.0%) antibiotics in tests to inhibit the growth of gram-negative bacteria.


2018 ◽  
Vol 42 (9) ◽  
pp. e13743 ◽  
Author(s):  
Chin Hong Geow ◽  
Mei Ching Tan ◽  
Swee Pin Yeap ◽  
Nyuk Ling Chin

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Xi-Zhen Chen ◽  
Wei Kevin Zhang ◽  
He-Bin Tang ◽  
Xiao-Jun Li ◽  
Gui-Hua Tian ◽  
...  

Liver cancer is one of the leading causes of cancerous deaths worldwide. At present, the treatment of hepatocellular carcinoma (HCC) remains to be a problem globally. Liushenwan (LSW), an ancient Chinese medicine previously used to treat localized infections, was recently reported to possess anticancer activity. Here in this study, we aim to examine the effect of LSW-ET (LSW-ET is the supernatant fraction of LSW from ultrasound assisted ethanol extraction) in prevention and treatment on nanodiethylnitrosamine- (nanoDEN-) induced HCC in mice. In nanoDEN-induced HCC mice treated with LSW-ET by oral (po) or intragastric gavage (ig), we observed an alleviation of serum ALT and AST levels, amelioration in histopathological stainings, and an inhibition in liver tumor growth. In addition, compared with the nanoDEN group, downregulation of multiple pivotal factors (COX-2,β-catenin, PCNA, and HMGB-1) was observed in LSW-ET-po and LSW-ET-ig groups. Taken together, the delivery of LSW-ET by oral could be a potential prevention and treatment of liver cancer.


2021 ◽  
Author(s):  
Yana Zhao ◽  
Huizhen Li ◽  
Zhijun Zhang ◽  
Zhiqing Ren ◽  
Fuhan Yang

Polyphenols display potential functional activities especially for rosmarinic acid (RosA) and caffeic acid (CafA). In this study, two different methods including ultrasonic-assisted ethanol extraction (60%) and ultrasound-assisted cellulase (≥ 15000...


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