Adverse physiologic effects of a common food additive potassium metabisulfite (E224) in laboratory rats

2022 ◽  
Author(s):  
Irfan Zia Qureshi ◽  
Nizam Ud Din ◽  
Ghulam Khadija ◽  
Aneeqa Shahzadi ◽  
Bakhtawer Rafiq ◽  
...  
Keyword(s):  
Food Additive ◽  
Laboratory Rats ◽  
Common Food

Evaluation on the effect of Common Food Additive by Cell Based Assay

2019 ◽  
Vol 12 (11) ◽  
pp. 5433
Author(s):  
K. Mythili ◽  
C. Vichitra ◽  
S. Gayatri ◽  
K. Chitra
Keyword(s):  
Food Additive ◽  
Common Food

Demonstrating adverse effects of a common food additive (sodium sulfite) on biochemical, cytological and histopathological parameters in tissues of albino Wister rats

2015 ◽  
Vol 7 (3) ◽  
pp. 234-242 ◽  
Author(s):  
Awad Abdel Twab Mahmoud ◽  
Gamal Mohamedin Hassan ◽  
Abdel Moneim Sadek Hassan ◽  
Abdel Krem Mohammed Abdel Latif ◽  
Mohamed Fawzy Ramadan
Keyword(s):  
Adverse Effects ◽  
Sodium Sulfite ◽  
Food Additive ◽  
Common Food

scholarly journals Changes in cell membranes of white blood cells treated with a common food additive E407a

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Anton Tkachenko ◽  
Anatolii Onishchenko ◽  
Yevgen Posokhov ◽  
Alexander Roshal ◽  
Valeriy Myasoedov ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Lipid Membranes ◽  
White Blood Cells ◽  
Proton Donor ◽  
Food Additive ◽  
Phospholipid Bilayer ◽  
Hydroxy Derivative ◽  
Common Food ◽  
High Concentrations ◽  
High Doses

Abstract Objectives To estimate the state of phospholipid bilayer of rats WBCs exposed to a common food additive E407a, which is used as a thickener and emulsifier, during 4 h using a fluorescent probe − ortho-hydroxy derivative of 2,5-diaryl-1,3-oxazole. Materials and methods Steady-state fluorescence spectroscopy: a study by the environment-sensitive fluores-cent probe − 2-(2′-hydroxy-phenyl)-5-phenyl-1,3-oxazole (probe O1O). Results Changes are detected in the spectra of the fluorescent probe bound to rat WBCs treated with the solutions of E407a of various concentrations in comparison with the corresponding spectra of the probe incubated with the untreated leukocytes. The decrease in polarity and proton-donor ability is observed in the lipid membranes of leukocytes in the region, where the probe locates. Conclusions Our findings suggest a higher dehydration of leukocyte membranes of rats treated with a common food additive E407a at high concentrations and, thus, indicate that exposure to high doses of E407a leads to the increase in the lipid order (i.e. to decrease in fluidity) of the membranes of rat WBCs.

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