scholarly journals Sulcal pattern variation in extant human endocasts

2019 ◽  
Vol 235 (4) ◽  
pp. 803-810
Author(s):  
Edwin J. Jager ◽  
Albert N. van Schoor ◽  
Jakobus W. Hoffman ◽  
Anna C. Oettlé ◽  
Caroline Fonta ◽  
...  
Keyword(s):  
Sulcal Pattern

scholarly journals Intergenerational Transmission of Cortical Sulcal Patterns from Mothers to their Children

2020 ◽  
Author(s):  
Banu Ahtam ◽  
Ted K Turesky ◽  
Lilla Zöllei ◽  
Julianna Standish ◽  
P Ellen Grant ◽  
...  
Keyword(s):  
Brain Development ◽  
Intergenerational Transmission ◽  
Environmental Influence ◽  
Fetal Brain ◽  
Comparison Method ◽  
Pattern Similarity ◽  
Fetal Brain Development ◽  
Pattern Comparison ◽  
The Right ◽  
Sulcal Pattern

Abstract Intergenerational effects are described as the genetic, epigenetic, as well as pre- and postnatal environmental influence parents have on their offspring’s behavior, cognition, and brain. During fetal brain development, the primary cortical sulci emerge with a distinctive folding pattern that are under strong genetic influence and show little change of this pattern throughout postnatal brain development. We examined intergenerational transmission of cortical sulcal patterns by comparing primary sulcal patterns between children (N = 16, age 5.5 ± 0.81 years, 8 males) and their biological mothers (N = 15, age 39.72 ± 4.68 years) as well as between children and unrelated adult females. Our graph-based sulcal pattern comparison method detected stronger sulcal pattern similarity for child–mother pairs than child-unrelated pairs, where higher similarity between child–mother pairs was observed mostly for the right lobar regions. Our results also show that child–mother versus child-unrelated pairs differ for daughters and sons with a trend toward significance, particularly for the left hemisphere lobar regions. This is the first study to reveal significant intergenerational transmission of cortical sulcal patterns, and our results have important implications for the study of the heritability of complex behaviors, brain-based disorders, the identification of biomarkers, and targets for interventions.

scholarly journals Temporal Lobe Sulcal Pattern and the Bony Impressions in the Middle Cranial Fossa: The Case of the El Sidrón (Spain) Neandertal Sample

2014 ◽  
Vol 297 (12) ◽  
pp. 2331-2341 ◽  
Author(s):  
Antonio Rosas ◽  
Angel Peña-Melián ◽  
Antonio García-Tabernero ◽  
Markus Bastir ◽  
Marco De La Rasilla
Keyword(s):  
Temporal Lobe ◽  
Middle Cranial Fossa ◽  
Cranial Fossa ◽  
Sulcal Pattern

Developments of sulcal pattern and subcortical structures of the forebrain in cynomolgus monkey fetuses: 7-tesla magnetic resonance imaging provides high reproducibility of gross structural changes

2009 ◽  
Vol 213 (4-5) ◽  
pp. 469-480 ◽  
Author(s):  
Kazuhiko Sawada ◽  
Xue-Zhi Sun ◽  
Katsuhiro Fukunishi ◽  
Masatoshi Kashima ◽  
Hiromi Sakata-Haga ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cynomolgus Monkey ◽  
Structural Changes ◽  
7 Tesla ◽  
Resonance Imaging ◽  
Subcortical Structures ◽  
High Reproducibility ◽  
Sulcal Pattern

Sulcal pattern of the anterior parahippocampal gyrus in the human adult

1997 ◽  
Vol 179 (4) ◽  
pp. 335-339 ◽  
Author(s):  
Joachim Hanke
Keyword(s):  
Parahippocampal Gyrus ◽  
Human Adult ◽  
Sulcal Pattern

scholarly journals Abnormal Left‐Hemispheric Sulcal Patterns in Adults With Simple Congenital Heart Defects Repaired in Childhood

2021 ◽  
Author(s):  
Benjamin Asschenfeldt ◽  
Lars Evald ◽  
Hyuk Jin Yun ◽  
Johan Heiberg ◽  
Leif Østergaard ◽  
...  
Keyword(s):  
Left Hemisphere ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Defects ◽  
Healthy Controls ◽  
Unique Identifier ◽  
Educational Support ◽  
Pattern Similarity ◽  
Neurodevelopmental Abnormalities ◽  
Sulcal Pattern

Background Children operated on for a simple congenital heart defect (CHD) are at risk of neurodevelopmental abnormalities. Abnormal cortical development and folding have been observed in fetuses with CHD. We examined whether sulcal folding patterns in adults operated on for simple CHD in childhood differ from those of healthy controls, and whether such differences are associated with neuropsychological outcomes. Methods and Results Patients (mean age, 24.5 years) who underwent childhood surgery for isolated atrial septal defect (ASD; n=33) or ventricular septal defect (VSD; n=30) and healthy controls (n=37) were enrolled. Sulcal pattern similarity to healthy controls was determined using magnetic resonance imaging and looking at features of sulcal folds, their intersulcal relationships, and sulcal graph topology. The sulcal pattern similarity values were tested for associations with comprehensive neuropsychological scores. Patients with both ASD and VSD had decreased sulcal pattern similarity in the left hemisphere compared with controls. The differences were found in the left temporal lobe in the ASD group and in the whole left hemisphere in the VSD group ( P =0.033 and P =0.039, respectively). The extent of abnormal left hemispheric sulcal pattern similarity was associated with worse neuropsychological scores (intelligence, executive function, and visuospatial abilities) in the VSD group, and special educational support in the ASD group. Conclusions Adults who underwent surgery for simple CHD in childhood display altered left hemisphere sulcal folding patterns, commensurate with neuropsychological scores for patients with VSD and special educational support for ASD. This may indicate that simple CHD affects early brain development. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03871881.

scholarly journals An Atypical Sulcal Pattern in Children with Disorders of the Corpus Callosum and Its Relation to Behavioral Outcomes

2020 ◽  
Vol 30 (9) ◽  
pp. 4790-4799
Author(s):  
Lana Vasung ◽  
Hyuk Jin Yun ◽  
Henry A Feldman ◽  
Patricia Ellen Grant ◽  
Kiho Im
Keyword(s):  
Corpus Callosum ◽  
Clinical Outcome ◽  
Behavioral Outcomes ◽  
Similarity Index ◽  
Careful Examination ◽  
Control Group ◽  
Graph Topology ◽  
Temporal Lobes ◽  
Occipital Lobes ◽  
Sulcal Pattern

Abstract Hypogenesis (hCC) and dysgenesis (dCC) of the corpus callosum (CC) are characterized by its smaller size or absence. The outcomes of these patients vary considerably and are unrelated to the size of the CC abnormality. The aim of the current study was to characterize the sulcal pattern in children with hCC and dCC and to explore its relation to clinical outcome. We used quantitative sulcal pattern analysis that measures deviation (similarity index, SI) of the composite or individual sulcal features (position, depth, area, and graph topology) compared to the control group. We calculated SI for each hemisphere and lobe in 11 children with CC disorder (hCC = 4, dCC = 7) and 15 controls. hCC and dCC had smaller hemispheric SI compared to controls. dCC subjects had smaller regional SI in the frontal and occipital lobes, which were driven by a smaller SI in a position or a graph topology. The significantly decreased SI gradient was found across groups only in the sulcal graph topology of the temporal lobes (controls > hCC > dCC) and was related to clinical outcome. Our results suggest that careful examination of sulcal pattern in hCC and dCC patients could be a useful biomarker of outcome.

Sonographic cerebral sulcal pattern in normal fetuses

2006 ◽  
Vol 30 (4) ◽  
pp. 299
Author(s):  
A. Ruiz ◽  
C. Sembely-Taveau ◽  
C. Paillet ◽  
D. Sirinelli
Keyword(s):  
Sulcal Pattern

scholarly journals Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease

2019 ◽  
Vol 30 (2) ◽  
pp. 476-487 ◽  
Author(s):  
Sarah U Morton ◽  
Lara Maleyeff ◽  
David Wypij ◽  
Hyuk Jin Yun ◽  
Jane W Newburger ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Pattern Analysis ◽  
De Novo ◽  
Neurodevelopmental Outcomes ◽  
Parietal Lobes ◽  
Pattern Similarity ◽  
Neurodevelopmental Abnormalities ◽  
Sulcal Pattern

AbstractNeurodevelopmental abnormalities are the most common noncardiac complications in patients with congenital heart disease (CHD). Prenatal brain abnormalities may be due to reduced oxygenation, genetic factors, or less commonly, teratogens. Understanding the contribution of these factors is essential to improve outcomes. Because primary sulcal patterns are prenatally determined and under strong genetic control, we hypothesized that they are influenced by genetic variants in CHD. In this study, we reveal significant alterations in sulcal patterns among subjects with single ventricle CHD (n = 115, 14.7 ± 2.9 years [mean ± standard deviation]) compared with controls (n = 45, 15.5 ± 2.4 years) using a graph-based pattern-analysis technique. Among patients with CHD, the left hemisphere demonstrated decreased sulcal pattern similarity to controls in the left temporal and parietal lobes, as well as the bilateral frontal lobes. Temporal and parietal lobes demonstrated an abnormally asymmetric left–right pattern of sulcal basin area in CHD subjects. Sulcal pattern similarity to control was positively correlated with working memory, processing speed, and executive function. Exome analysis identified damaging de novo variants only in CHD subjects with more atypical sulcal patterns. Together, these findings suggest that sulcal pattern analysis may be useful in characterizing genetically influenced, atypical early brain development and neurodevelopmental risk in subjects with CHD.

ACC Sulcal Patterns and Their Modulation on Cognitive Control Efficiency Across Lifespan: A Neuroanatomical Study on Bilinguals and Monolinguals

2018 ◽  
Vol 29 (7) ◽  
pp. 3091-3101 ◽  
Author(s):  
Nicola Del Maschio ◽  
Simone Sulpizio ◽  
Davide Fedeli ◽  
Keerthi Ramanujan ◽  
Guosheng Ding ◽  
...  
Keyword(s):  
Cognitive Control ◽  
Structural Mri ◽  
Anterior Cingulate ◽  
Healthy Individuals ◽  
Cognitive Efficiency ◽  
Environmental Background ◽  
Function Relationship ◽  
Dynamic Interplay ◽  
Sulcal Pattern ◽  
A Performance

Abstract The anterior cingulate cortex (ACC) is a key structure implicated in the regulation of cognitive control (CC). Previous studies suggest that variability in the ACC sulcal pattern—a neurodevelopmental marker unaffected by maturation or plasticity after birth—is associated with intersubject differences in CC performance. Here, we investigated whether bilingual experience modulates the effects of ACC sulcal variability on CC performance across the lifespan. Using structural MRI, we first established the distribution of the ACC sulcal patterns in a large sample of healthy individuals (N = 270) differing on gender and ethnicity. Second, a participants’ subsample (N = 157) was selected to test whether CC performance was differentially affected by ACC sulcation in bilinguals and monolinguals across age. A prevalent leftward asymmetry unaffected by gender or ethnicity was reported. Sulcal variability in the ACC predicted CC performance differently in bilinguals and monolinguals, with a reversed pattern of structure–function relationship: asymmetrical versus symmetrical ACC sulcal patterns were associated with a performance advantage in monolinguals and a performance detriment to bilinguals and vice versa. Altogether, these findings provide novel insights on the dynamic interplay between early neurodevelopment, environmental background and cognitive efficiency across age.

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