scholarly journals The safety and tolerability of Annona muricata leaf extract: a systematic review

2019 ◽  
Vol 72 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Wai‐Jo Jocelin Chan ◽  
Andrew J. McLachlan ◽  
Jane R. Hanrahan ◽  
Joanna E. Harnett
Keyword(s):  
Systematic Review ◽  
Leaf Extract ◽  
Annona Muricata

scholarly journals Anti-bacterial activity of Annona muricata Linnaeus extracts: a systematic review

2021 ◽  
Author(s):  
Ricardo Mendes da SILVA ◽  
Isabella de Matos Mendes da SILVA ◽  
Maria Manuela ESTEVINHO ◽  
Leticia M. ESTEVINHO
Keyword(s):  
Systematic Review ◽  
Bacterial Activity ◽  
Annona Muricata

PHOTOCATALYTIC DEGRADATION OF METHYLENE BLUE USING IRON OXIDE NANOPARTICLES SYNTHESIZED USING ANNONA MURICATA LEAF EXTRACT

2020 ◽  
pp. 46-51
Author(s):  
BEENA JOSE ◽  
FEMY THOMAS
Keyword(s):  
Electron Microscopy ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Leaf Extract ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticles ◽  
Annona Muricata ◽  
Aqueous Leaf Extract ◽  
Oxide Nanoparticle ◽  
Uv Visible

Objective: The objective of the present study is the synthesis of iron oxide nanoparticles using Annona muricata aqueous leaf extract, characterization of the synthesized nanoparticles and evaluation of the antibacterial, photocatalytic activity and cytotoxicity. Methods: The iron oxide nanoparticle was synthesized using Annona muricata aqueous leaf extract and the crystal structure of the iron oxide nanoparticle was determined by UV-Visible spectroscopy, Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR). The in vitro cytotoxicity of iron oxide nanoparticles was evaluated using Dalton’s lymphoma ascites cells and the antibacterial assay was conducted using agar well diffusion method. Results: The UV-Visible spectrum of iron oxide nanoparticle showed a maximum absorption peak at 265 nm. This is the XRD pattern of iron oxide nanoparticles exhibited a distinct peak at 26.029 (2θ), accounting for crystal plane (211). SEM images revealed that the synthesized iron oxide nanoparticles were aggregated as irregular sphere shapes with rough surfaces. TEM image reveals the size of the synthesized iron oxide nanoparticles are spherical in shape with an average size of 20 nm. Green synthesized iron oxide nanoparticles using Annona muricata leaf extract effectively degraded methylene blue dye. Conclusion: This study showed that the synthesized iron oxide nanoparticles using Annona muricata aqueous leaf extract exhibited pronounced antibacterial, anticancer and photocatatytic activity and can be used in the textile industry for the purification of water contaminated with carcinogenic textile dyes. It can also be used as an external antiseptic in the prevention and treatment of bacterial infections.

scholarly journals The Value of Caspase-3 after the Application of Annona muricata Leaf Extract in COLO-205 Colorectal Cancer Cell Line

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Murdani Abdullah ◽  
Ari Fahrial Syam ◽  
Sofy Meilany ◽  
Bayu Laksono ◽  
Oryza Gryagus Prabu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Leaf Extract ◽  
Caspase 3 ◽  
Cancer Cell Line ◽  
Negative Control ◽  
Colorectal Cancer Cell ◽  
Colorectal Cancer Cell Line ◽  
Annona Muricata

Annona muricata, commonly known as soursop, contains annonacin, acetogenin, and polyphenol which are known to have chemopreventive effects on cancer. In this study, we tend to evaluate the apoptosis-inducing effect of soursop (Annona muricata) leaf extract on the colorectal cancer cell line COLO-205 through the activities of caspase-3 which is a marker of cell apoptosis. Cell cultures were incubated with soursop leaf with a concentration of 10 μg/ml and then compared with those of the incubated positive control leucovorin 10 μg/ml and placebo as a negative control. The apoptotic activity of caspase-3 was measured with ELISA. After the administration of each treatment in the colorectal cancer cell line COLO-205, the expression of caspase-3 activity was 1422 ng/ml after incubation with the extract of Annona muricata leaves, 1373 ng/ml after the administration of leucovorin, and 1297 ng/ml in the one with placebo. Annona muricata leaf extract elevated caspase-3 by 1.09 times compared to that of the pure cell line. Annona muricata leaf extract had a higher value of caspase-3 activity than leucovorin and placebo in the COLO-205 colorectal cancer cell line. These results may suggest that Annona muricata leaf extract had anticancer properties by enhancing caspase-3 activity which is a proapoptotic marker.

Effects of Aqueous Leaf Extract of Annona muricata on Pregnancy and Pregnancy Outcome

2017 ◽  
Vol 12 (1) ◽  
pp. 1-6
Author(s):  
Enyi Obianuju ◽  
Okorie Pamela ◽  
Iyare Eghosa ◽  
Ugwu Princewill ◽  
Anyaehie Bond
Keyword(s):  
Pregnancy Outcome ◽  
Leaf Extract ◽  
Annona Muricata ◽  
Aqueous Leaf Extract
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