scholarly journals The dog erythrocyte antigen 1 blood group in nondomesticated canids and compatibility testing between domestic dog and nondomesticated canid blood

2020 ◽  
Vol 34 (6) ◽  
pp. 2365-2373
Author(s):  
Thomas Charpentier ◽  
Thierry Petit ◽  
Maryline Guidetti ◽  
Isabelle Goy‐Thollot
Keyword(s):  
Blood Group ◽  
Domestic Dog ◽  
Erythrocyte Antigen ◽  
Dog Erythrocyte

scholarly journals The breed prevalence of Dog Erythrocyte Antigen 1.1 in the Onderstepoort area of South Africa and its significance in selection of canine blood donors

2002 ◽  
Vol 73 (2) ◽  
Author(s):  
L.L. Van der Merwe ◽  
L.S. Jacobson ◽  
J.G. Pretorius
Keyword(s):  
South Africa ◽  
Blood Group ◽  
Blood Donors ◽  
German Shepherd ◽  
Animal Blood ◽  
Breed Differences ◽  
Life Threatening ◽  
Erythrocyte Antigen ◽  
N 93 ◽  
Dog Erythrocyte

The blood group antigen Dog Erythrocyte Antigen (DEA) 1.1 is clinically the most important canine blood group as DEA 1.1 antibodies are capable of causing acute haemolytic, potentially life-threatening transfusion reactions. Dogs do not have naturally occurring antibodies to DEA 1.1 but are rapidly sensitised by the first incompatible transfusion. The prevalence of DEA 1.1 in the general dog population is estimated at 42-46 %. Canine blood donors registered with the Onderstepoort Animal Blood Bank (n = 93) as well as potential donors (n = 140) were typed for DEA 1.1 using a monoclonal antibody card kit. All dogs came from the Onderstepoort area, near Pretoria, Gauteng province, South Africa. Overall prevalence of DEA 1.1 was 47 %. Prevalence was 47 % in purebred dogs and 48 % in mongrels. Distinct breed differences were noted with less than 20 % of German shepherd dogs and Boxers and greater than 75 % of Rottweilers, Great Danes, St Bernards and Dalmations testing DEA 1.1 positive. Knowledge of local breed differences will increase effectiveness of blood donor recruitment.

scholarly journals Frequency of dog erythrocyte antigen 1 blood group and risk of incompatible transfusion in dogs of different breeds and mongrels from the city of Salvador - BA, Brazil

2019 ◽  
Vol 56 (3) ◽  
pp. e154865
Author(s):  
Suzana Cláudia Spínola dos Santos ◽  
Mariane Melo dos Santos ◽  
Wellington Francisco Rodrigues ◽  
Roberto Meyer ◽  
Maria de Fátima Dias Costa
Keyword(s):  
Flow Cytometry ◽  
Blood Group ◽  
Blood Type ◽  
Blood Transfusions ◽  
Blood Typing ◽  
Reaction Test ◽  
Erythrocyte Antigen ◽  
The City ◽  
Dog Erythrocyte ◽  
Group 1

The dog erythrocyte antigen 1 (DEA 1) is the most immunogenic blood group in dogs, and blood transfusions may trigger some undesirable effects in veterinary patients, which are directly associated with incompatible transfusions. The present study aimed to investigate the frequency of positive DEA 1 blood group in blood donor dogs from a blood bank in Salvador, Bahia, Brazil, and also to calculate the risk of managing incompatible blood in both first and second transfusion. A number of 203 dogs of different breeds, aged between 1 and 8 years, weighing 28 kg, with no degree of kinship and of both sexes in Salvador - BA, Brazil were evaluated to investigate the blood type DEA 1 frequency, by means of chromatography and flow cytometry tests for blood typing. The risk of incompatible blood transfusion in either a first or a second transfusion was also calculated. The frequency of the DEA 1 group ranged from 0% to 100% in various breeds, but with a mean positivity of 62.07% (126/203). And the lowest risk of an DEA 1 negative animal receiving DEA 1 positive blood within the group of animals evaluated was 0.92% at a first transfusion; and the risk of the same animal receiving incompatible blood for the DEA group 1 in the second transfusion was 0.008%. The highest risk of an DEA 1 negative animal receiving DEA 1 positive blood from these animals was 69.12%; and the risk of receiving incompatible blood for DEA 1 was 47.77%. In conclusion, the frequency of the DEA 1 group varied between the studied breeds and the risk of incompatible blood transfusions varies according to donor and recipiente breeds, but this can be overridden if blood typing tests are performed along with the cross-reaction test for compatibility.

scholarly journals A study on the prevalence of dog erythrocyte antigen 1.1 and detection of canine Babesia by polymerase chain reaction from apparently healthy dogs in a selected rural community in Zimbabwe

2016 ◽  
Vol 87 (1) ◽  
Author(s):  
Solomon Dhliwayo ◽  
Tariro A. Makonese ◽  
Belinda Whittall ◽  
Silvester M. Chikerema ◽  
Davies M. Pfukenyi ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Blood Group ◽  
Blood Type ◽  
Chain Reaction ◽  
Blood Typing ◽  
Life Threatening ◽  
Polymerase Chain ◽  
Erythrocyte Antigen ◽  
Babesia Spp ◽  
Dog Erythrocyte

A study was carried out to determine the prevalence of blood group antigen dog erythrocyte antigen (DEA) 1.1 in mixed breed dogs in rural Chinamhora, Zimbabwe. DEA 1.1 is clinically the most important canine blood group as it is the most antigenic blood type; hence, DEA 1.1 antibodies are capable of causing acute haemolytic, potentially life-threatening transfusion reactions. In this study, blood samples were collected from 100 dogs in Chinamhora, and blood typing was carried out using standardised DEA 1.1 typing strips with monoclonal anti–DEA 1.1 antibodies (Alvedia® LAB DEA 1.1 test kits). Polymerase chain reaction for detecting Babesia spp. antigen was carried out on 58 of the samples. Of the 100 dogs, 78% were DEA 1.1 positive and 22% were DEA 1.1 negative. A significantly (p = 0.02) higher proportion of females (90.5%) were DEA 1.1 positive than males (69.0%). The probability of sensitisation of recipient dogs following first-time transfusion of untyped or unmatched blood was 17.2%, and an approximately 3% (2.95%) probability of an acute haemolytic reaction following a second incompatible transfusion was found. Babesia spp. antigen was found in 6.9% of the samples. No significant relationship (χ2 = 0.56, p = 0.45) was found between DEA 1.1 positivity and Babesia spp. antigen presence. Despite a low probability of haemolysis after a second incompatibility transfusion, the risk remains present and should not be ignored. Hence, where possible, blood typing for DEA 1.1 is recommended. A survey of DEA 3, 4, 5 and 7 in various breeds is also recommended.

Analytic characterization of flow cytometric assays for detection of immunoglobulin G on canine erythroid cells, including detection of dog erythrocyte antigen 1 on erythroid precursors

2018 ◽  
Vol 79 (11) ◽  
pp. 1123-1132
Author(s):  
Cynthia A. Lucidi ◽  
John A. Gerlach ◽  
Susan Forney ◽  
L. Ari Jutkowitz ◽  
Michael A. Scott
Keyword(s):  
Immunoglobulin G ◽  
Erythroid Cells ◽  
Flow Cytometric ◽  
Erythroid Precursors ◽  
Erythrocyte Antigen ◽  
Dog Erythrocyte

Flow cytometric assessment of canine erythrocytes and platelets for dog erythrocyte antigen 1.1

2011 ◽  
Vol 40 (4) ◽  
pp. 435-443 ◽  
Author(s):  
Cynthia de A. Lucidi ◽  
Regina K. Takahira ◽  
John A. Gerlach ◽  
John M. Davis ◽  
Kenneth A. Schwartz ◽  
...  
Keyword(s):  
Flow Cytometric ◽  
Erythrocyte Antigen ◽  
Dog Erythrocyte

scholarly journals Alloimmunization of a dog erythrocyte antigen 1− dog transfused with weakly dog erythrocyte antigen 1+ blood

2019 ◽  
Vol 33 (5) ◽  
pp. 2037-2045 ◽  
Author(s):  
Maryline Guidetti ◽  
Isabelle Goy‐Thollot ◽  
Catherine Boisvineau ◽  
Urs Giger
Keyword(s):  
Erythrocyte Antigen ◽  
Dog Erythrocyte

Prevalence of dog erythrocyte antigen 1.1 in galgos (Spanish greyhounds)

2014 ◽  
Vol 174 (14) ◽  
pp. 351-351 ◽  
Author(s):  
I. Mesa-Sanchez ◽  
R. Ruiz de Gopegui-Fernández ◽  
M. M. Granados-Machuca ◽  
A. Galan-Rodriguez
Keyword(s):  
Erythrocyte Antigen ◽  
Dog Erythrocyte

Prevalence of dog erythrocyte antigen 1.1 in dogs in Switzerland evaluated with the gel column technique

2011 ◽  
Vol 153 (8) ◽  
pp. 369-374 ◽  
Author(s):  
B. Riond ◽  
E. Schuler ◽  
E. Rogg ◽  
R. Hofmann-Lehmann ◽  
H. Lutz
Keyword(s):  
Erythrocyte Antigen ◽  
Dog Erythrocyte

scholarly journals Comparison of cross-matching method for detection of DEA 7 blood incompatibility

2018 ◽  
Vol 30 (6) ◽  
pp. 911-916 ◽  
Author(s):  
Eva Spada ◽  
Roberta Perego ◽  
Luis Miguel Viñals Flórez ◽  
Maria del Rosario Perlado Chamizo ◽  
Luciana Baggiani ◽  
...  
Keyword(s):  
Reference Method ◽  
Kappa Coefficient ◽  
Plasma Samples ◽  
Matching Method ◽  
Double Blind ◽  
Perfect Agreement ◽  
Erythrocyte Antigen ◽  
Cross Matching ◽  
Cross Match ◽  
Dog Erythrocyte

We compared 3 major cross-match (XM) tests to identify dog erythrocyte antigen (DEA) 7 blood incompatibilities in dogs as a result of anti–DEA 7 antibodies: gel (GEL), standard tube (TUBE) agglutination, and immunochromatography strips (STRIP). Blood samples from 42 dogs were typed for DEA 7; 2 tested DEA 7–positive (DEA 7+). The 40 DEA 7–negative (DEA 7–) plasma samples were cross-matched against the 2 DEA 7+ and 3 DEA 7– red blood cell (RBC) samples by GEL to identify samples with anti–DEA 7 antibodies. Twenty DEA 7– plasma samples without and with anti–DEA 7 antibodies were cross-matched with samples of the 2 DEA 7+ RBCs in a double-blind fashion using the TUBE and STRIP XM methods. GEL results were used as the reference method for comparison. To determine relationships between results, 2 × 2 tables were used. Cohen kappa coefficient (κ) was calculated between results of GEL and the other 2 methods. With GEL, 21 of 40 XM tests were positive and 19 of 40 negative for anti–DEA 7 antibodies. The same results were obtained by TUBE, whereas only 1 of 40 XM tests was positive by STRIP. There was a statistically significant relationship between results of GEL and TUBE ( p < 0.000) with perfect agreement (κ = 1.000), but not between GEL and STRIP results ( p = 1.000) in which agreement was equivalent to chance (κ = 0.0453). The GEL and TUBE XM tests, but not STRIP, are useful methods for identification of DEA 7 incompatibilities caused by anti–DEA 7 antibodies.

Frequency of dog erythrocyte antigen 1.1 in 4 breeds native to different areas in Turkey

2011 ◽  
Vol 40 (4) ◽  
pp. 518-523 ◽  
Author(s):  
Elif Ergul Ekiz ◽  
Murat Arslan ◽  
Mukaddes Ozcan ◽  
Guldal Inal Gultekin ◽  
Ozlem Yildiz Gulay ◽  
...  
Keyword(s):  
Erythrocyte Antigen ◽  
Dog Erythrocyte
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