scholarly journals Food Allergy Treatment Value: Child Caregiver and Patient Perspectives

2021 ◽  
Author(s):  
Moaz Abdelwadoud ◽  
Sanaz Eftekhari ◽  
Hannah Jaffee ◽  
Melanie Carver ◽  
T. Joseph Mattingly
Keyword(s):  
Food Allergy ◽  
Patient Perspectives ◽  
Allergy Treatment ◽  
Child Caregiver

Postbiotics: A novel strategy in food allergy treatment

2020 ◽  
Vol 61 (3) ◽  
pp. 492-499 ◽  
Author(s):  
Aziz Homayouni Rad ◽  
Leili Aghebati Maleki ◽  
Hossein Samadi Kafil ◽  
Amin Abbasi
Keyword(s):  
Food Allergy ◽  
Allergy Treatment ◽  
Novel Strategy

scholarly journals Food Allergies: Current and Future Treatments

Medicina ◽  
2019 ◽  
Vol 55 (5) ◽  
pp. 120 ◽  
Author(s):  
Amelia Licari ◽  
Sara Manti ◽  
Alessia Marseglia ◽  
Ilaria Brambilla ◽  
Martina Votto ◽  
...  
Keyword(s):  
Food Allergy ◽  
Adverse Reactions ◽  
Public Health Problem ◽  
Food Allergies ◽  
Dietary Restrictions ◽  
Related Risk ◽  
Promising Therapeutic Approach ◽  
Significant Burden ◽  
Allergy Treatment

Food allergies are an increasingly public health problem, affecting up to 10% of children and causing a significant burden on affected patients, resulting in dietary restrictions, fear of accidental ingestion and related risk of severe reactions, as well as a reduced quality of life. Currently, there is no specific cure for a food allergy, so the only available management is limited to strict dietary avoidance, education on prompt recognition of symptoms, and emergency treatment of adverse reactions. Several allergen specific- and nonspecific-therapies, aiming to acquire a persistent food tolerance, are under investigation as potential treatments; however, to date, only immunotherapy has been identified as the most promising therapeutic approach for food allergy treatment. The aim of this review is to provide an updated overview on changes in the treatment landscape for food allergies.

scholarly journals A Comprehensive Review on Natural Bioactive Compounds and Probiotics as Potential Therapeutics in Food Allergy Treatment

2020 ◽  
Vol 11 ◽  
Author(s):  
Kunal Pratap ◽  
Aya C. Taki ◽  
Elecia B. Johnston ◽  
Andreas L. Lopata ◽  
Sandip D. Kamath
Keyword(s):  
Food Allergy ◽  
Bioactive Compounds ◽  
Comprehensive Review ◽  
Allergy Treatment ◽  
Potential Therapeutics

scholarly journals Food Allergy Treatment Value: Child Caregiver and Patient Perspectives

2020 ◽  
Author(s):  
Moaz Abdelwadoud ◽  
Sanaz Eftekhari ◽  
Hannah Jaffee ◽  
Melanie Carver ◽  
T. Mattingly II
Keyword(s):  
Food Allergy ◽  
Treatment Outcomes ◽  
Delphi Study ◽  
Food Selection ◽  
Treatment Options ◽  
Clinical Effectiveness ◽  
The United States ◽  
Allergic Reactions ◽  
Major Health Problem ◽  
Allergy Treatment

Background: Food allergy is a major health problem that significantly impacts quality of life (QoL). There is growing focus to evaluate food allergy related QoL and treatment value beyond the clinical effectiveness perspective by engaging patients and caregivers. We aimed to identify and prioritize outcomes important to food allergy parents of children and patients allergic to milk, egg, and/or peanut, to guide comparative effectiveness research (CER) that focuses on evaluating food allergy treatment decisions. Methods: We conducted a modified 3-round Delphi study to identify and derive consensus on priority treatment outcomes for parents of children and adult patients with diagnosed allergies to at least one of three major allergenic foods (milk, egg, and peanut) from across the United States. Results: Round 1 yielded 44 statements for round 2, and 39 statements reached the agreement level for round 3 ranking. Statements were organized under 4 sections: 1) food allergy problems, 2) treatment experiences, 3) important treatment outcomes, and 4) value of different treatment options. Conclusion: Food allergy parents and patients face several social, psychological, medical, healthcare, financial, food selection, and awareness challenges. The areas of consensus on important treatment outcomes revealed shared priority for reducing the risk of potentially fatal allergic reactions and having reliable treatments. The most valued treatment options reflect hope for permanent cure and fear of serious allergic reactions.

scholarly journals Progress of Home-Based Food Allergy Treatment during the Coronavirus Disease Pandemic in Japan: A Cross-Sectional Multicenter Survey

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 919
Author(s):  
Akihiro Maeta ◽  
Yuri Takaoka ◽  
Atsuko Nakano ◽  
Yukiko Hiraguchi ◽  
Masaaki Hamada ◽  
...  
Keyword(s):  
Food Allergy ◽  
Allergic Diseases ◽  
Oral Immunotherapy ◽  
Medical Care System ◽  
Cross Sectional ◽  
State Of Emergency ◽  
Emergency Visits ◽  
Home Based ◽  
Multicenter Survey ◽  
Allergy Treatment

The coronavirus disease 2019 (COVID-19) pandemic’s impact on food allergy treatment such as home-based oral immunotherapy (OIT) is not known. This cross-sectional, questionnaire-based anonymized survey screened 2500 parents of children with allergic diseases and was conducted in the pediatric outpatient clinics of 24 hospitals. Basic clinical data of the children were collected along with the degree of allergy control, parental anxiety about emergency visits, and the risk of COVID-19 in the first state of emergency. A total of 2439 (97.6%) questionnaires were collected, and 1315 parents who were instructed to initiate home-based OIT for their children were enrolled (OIT group). Subjective OIT progress compared to before the COVID-19 pandemic was ascertained as “Full”, “Middle”, “Low”, “Little”, and “Stop” in 264 (20.1%), 408 (31.0%), 384 (29.2%), 203 (15.4%), and 56 (4.3%) participants, respectively. Anxiety about emergency visits and the risk of COVID-19 were negatively associated with the subjective OIT progress. In Japan, approximately half of the children continued smoothly the home-based OIT during the COVID-19 pandemic. Parents with high levels of anxiety about the disruption of the medical care system due to COVID-19 and the risk of COVID-19 did not experience a smooth continuation of home-based OIT.

scholarly journals Peran Imunoterapi pada Tatalaksana Alergi Makanan (The Role of Immunotherapy in Food Allergy)

2020 ◽  
Vol 6 (2) ◽  
pp. 19-28
Author(s):  
Hendra Hendra Hendra
Keyword(s):  
Food Allergy ◽  
Immune System ◽  
Oral Immunotherapy ◽  
World Allergy Organization ◽  
New Paradigm ◽  
Allergy Immunotherapy ◽  
Immunologic Reaction ◽  
Allergy Treatment

AbstrakAlergi makanan merupakan reaksi  imun yang terjadi setelah paparan terhadap makanan tertentu. World Allergy Organization (WAO) melaporkan 22% penduduk dunia menderita alergi dan terus meningkat setiap tahun.  Data tahun 2014, diperkirakan kasus alergi makanan terjadi pada 5% dewasa dan 8% pada anak-anak. Alergi makanan adalah bagian dari reaksi hipersensitivitas, yakni hiperesponsivitas imunologik terhadap antigen spesifik, dapat berasal dari makanan atau mikroorganisme patogen maupun  produknya. Alergi  makanan menunjukkan gejala klinis lokal ataupun sistemik. Perkembangan ilmu pengetahuan mengarahkan perubahan paradigma dari pencegahan alergi yang berupa tindakan  menghindari alergen  ke arah desensitisasi dan induksi aktif toleransi imunologik. Imunoterapi dibuat berdasarkan hubungan dengan alergen spesifik. Sebagai dasar teori yaitu dengan  melakukan  peningkatan  paparan secara bertahap seorang penderita dengan alergen yang spesifik, maka diharapkan akan terjadi suatu  proses desensitisasi atau peningkatan toleransi terhadap alergen tersebut. Oral imunoterapi melibatkan makanan yang merupakan alergen dan dikonsumsi bertahap dengan peningkatan dosis. Sebagian besar protokol oral imunoterapi meliputi fase eskalasi, diikuti dengan peningkatan dosis dan dosis maintenance. Optimasi imunoterapi dapat dilakukan dengan modifikasi protokol seperti dosis, durasi, probiotik dengan imunoterapi, ataupun modifikasi dengan alergen multipel.Kata kunci: alergi makanan, imunoterapi AbstractFood allergy is immunologic reaction after food exposures. World Allergy Organization (WAO) reported 22% worldwide have allergy and keep increasing. In 2014, food allergy been speculated 5% in adult and 8% in child. Food allergy is a part of hypersensitivity, as hyperresponsiveness in immune system with spesific antigen from food. Food allergy can manifest as local or systemic. New paradigm in food allergy treatment, shifted from avoid the allergen to desensitization and tolerance. In patient with gradual exposure with spesific allergen, desensitization and tolerance been expected. Oral immunotherapy involve food consuming and increased the doses. It consist of escalation, increasing doses and maintenance. For optimizing immunotherapy, it can been modified with dosage, duration, combined with probiotic or with multiple ellergen.       Keywords: food allergy, immunotherapy

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