scholarly journals Peran Imunoterapi pada Tatalaksana Alergi Makanan (The Role of Immunotherapy in Food Allergy)

2020 ◽  
Vol 6 (2) ◽  
pp. 19-28
Author(s):  
Hendra Hendra Hendra

AbstrakAlergi makanan merupakan reaksi  imun yang terjadi setelah paparan terhadap makanan tertentu. World Allergy Organization (WAO) melaporkan 22% penduduk dunia menderita alergi dan terus meningkat setiap tahun.  Data tahun 2014, diperkirakan kasus alergi makanan terjadi pada 5% dewasa dan 8% pada anak-anak. Alergi makanan adalah bagian dari reaksi hipersensitivitas, yakni hiperesponsivitas imunologik terhadap antigen spesifik, dapat berasal dari makanan atau mikroorganisme patogen maupun  produknya. Alergi  makanan menunjukkan gejala klinis lokal ataupun sistemik. Perkembangan ilmu pengetahuan mengarahkan perubahan paradigma dari pencegahan alergi yang berupa tindakan  menghindari alergen  ke arah desensitisasi dan induksi aktif toleransi imunologik. Imunoterapi dibuat berdasarkan hubungan dengan alergen spesifik. Sebagai dasar teori yaitu dengan  melakukan  peningkatan  paparan secara bertahap seorang penderita dengan alergen yang spesifik, maka diharapkan akan terjadi suatu  proses desensitisasi atau peningkatan toleransi terhadap alergen tersebut. Oral imunoterapi melibatkan makanan yang merupakan alergen dan dikonsumsi bertahap dengan peningkatan dosis. Sebagian besar protokol oral imunoterapi meliputi fase eskalasi, diikuti dengan peningkatan dosis dan dosis maintenance. Optimasi imunoterapi dapat dilakukan dengan modifikasi protokol seperti dosis, durasi, probiotik dengan imunoterapi, ataupun modifikasi dengan alergen multipel.Kata kunci: alergi makanan, imunoterapi AbstractFood allergy is immunologic reaction after food exposures. World Allergy Organization (WAO) reported 22% worldwide have allergy and keep increasing. In 2014, food allergy been speculated 5% in adult and 8% in child. Food allergy is a part of hypersensitivity, as hyperresponsiveness in immune system with spesific antigen from food. Food allergy can manifest as local or systemic. New paradigm in food allergy treatment, shifted from avoid the allergen to desensitization and tolerance. In patient with gradual exposure with spesific allergen, desensitization and tolerance been expected. Oral immunotherapy involve food consuming and increased the doses. It consist of escalation, increasing doses and maintenance. For optimizing immunotherapy, it can been modified with dosage, duration, combined with probiotic or with multiple ellergen.       Keywords: food allergy, immunotherapy

2020 ◽  
Vol 145 (2) ◽  
pp. AB244
Author(s):  
Yamini Virkud ◽  
Rachel Kelly ◽  
Sarita Patil ◽  
Bert Ruiter ◽  
Neal Smith ◽  
...  

Allergy ◽  
2020 ◽  
Vol 75 (6) ◽  
pp. 1337-1346 ◽  
Author(s):  
Edwin H. Kim ◽  
Arvil Wesley Burks

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 919
Author(s):  
Akihiro Maeta ◽  
Yuri Takaoka ◽  
Atsuko Nakano ◽  
Yukiko Hiraguchi ◽  
Masaaki Hamada ◽  
...  

The coronavirus disease 2019 (COVID-19) pandemic’s impact on food allergy treatment such as home-based oral immunotherapy (OIT) is not known. This cross-sectional, questionnaire-based anonymized survey screened 2500 parents of children with allergic diseases and was conducted in the pediatric outpatient clinics of 24 hospitals. Basic clinical data of the children were collected along with the degree of allergy control, parental anxiety about emergency visits, and the risk of COVID-19 in the first state of emergency. A total of 2439 (97.6%) questionnaires were collected, and 1315 parents who were instructed to initiate home-based OIT for their children were enrolled (OIT group). Subjective OIT progress compared to before the COVID-19 pandemic was ascertained as “Full”, “Middle”, “Low”, “Little”, and “Stop” in 264 (20.1%), 408 (31.0%), 384 (29.2%), 203 (15.4%), and 56 (4.3%) participants, respectively. Anxiety about emergency visits and the risk of COVID-19 were negatively associated with the subjective OIT progress. In Japan, approximately half of the children continued smoothly the home-based OIT during the COVID-19 pandemic. Parents with high levels of anxiety about the disruption of the medical care system due to COVID-19 and the risk of COVID-19 did not experience a smooth continuation of home-based OIT.


2019 ◽  
Vol 11 (2) ◽  
pp. 79-86
Author(s):  
Cindy Ayustin Noya ◽  
Angkit Kinasih ◽  
Venti Agustina ◽  
R.Rr Maria Dyah Kurniasari

Infeksi saluran pernafasan akut atau yang sering disebut ISPA merupakan infeksi pada saluran pernafasan baik saluran pernafasan atas atau bawah.ISPA juga kebanyakan terjadi pada anak balita karena daya tahan tubuh mereka tidak kuat dalam menghadapi penyakit ISPA. ISPA mengakibatkan kematiansekitar15%-20% per tahun pada usia balita di Negara berkembang. Tujuan penelitian ini adalah untuk mengetahui dan menganalisa peran ibu dalam meningkatkan sistem imun anak dengan ISPA.Metode penelitian yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan sampel purposive sampling.Populasi dan sampel penelitian ini adalah ibu yang mempunyai anak dengan riwayat dan saat ini menderita penyakit ISPA di Batu Gajah Kota Ambon.Partisipan dalam penelitian ini berjumlah 5 orang. Hasil dari penelitian mendapati 4 kategori yaitu pemberian nutrisi pada anak untuk memenuhi kebutuhan agar sistem imunnya terjaga, kebersihan lingkungan, peran ibu dalam melakukan pencegahan pada anaknya yang mengalami ISPA, dan  peran ibu dalam menjaga dan mempertahankan kesehatan anaknya.   Kata kunci: peran ibu, sistem imun, ispa THE ROLE OF MOTHERS IN INCREASING IMMUNE SYSTEM OF CHILDREN WITH ACUTE RESPIRATORY INFECTION    ABSTRACT Acute respiratory infections or often called ARI is an infection of the upper or lower respiratory tract. ARI occurs mostly in children under the age of five because their endurance is not strong in dealing with ARI. ARI results in deaths of around 15%-20% per year at the age of under-five in developing countries. The purpose of this study was to determine and analyze the role of mothers in improving the immune system of children against ARI. The research method used in this study was qualitative descriptive with a purposive sampling sample. Respondents and samples of this study were five mothers who had children with a history of ARI and currently suffering from the disease in Batu Gajah, Ambon City. The results of the study found 4 categories, namely providing nutrition to children to meet their needs so that their immune systems are maintained, clean environment, mother's role in preventing children with ARI, and mother's role to preserve and maintain the health of their children. The findings indicated that in terms of coping or improving the immune system of a child to avoid ARI, it is necessary to have role the of mothers in providing nutrition so that the immune system is boosted, besides that the mother can prevent and protect her child from various diseases, especially ARI. Keywords: role of mothers, immune system, acute respiratory infections


2018 ◽  
Vol 2 (1) ◽  
pp. 52-63
Author(s):  
Ansori Ansori

The use of various methods will greatly help students in achieving learning goals. As role play method is one way mastery of learning materials through the development of imagination and appreciation of students on learning materials. Data collection techniques in this study are observation, interviews, and documentation. To analyze the data in this research using data analysis technique of Miles and Huberman model that is data reduction (Data Reduction), data presentation (Data Display) and conclusion (Conclution Drawing / verification) The findings in this research is innovation of role play method can change paradigm to the new paradigm so that the role of the teacher is more as a facilitator, counselor, consultant, and comrade study Flexible schedule, open as needed Learning directed by students themselves Problem-based, project, real world, real action, and reflection Design and investigation. Computers as tools, and dynamic media presentations.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 259-261
Author(s):  
Aamir Khan ◽  
Rajni K. Gurmule

Vasavaleha is one of the best medicine given for respiratory diseases. Corona viruses typically affect the respiratory system, causing symptoms such as coughing, fever and shortness of breath. It also affects host immune system of human body. Spreading rate of this disease is very high. Whole world is seeking for the treatment which can uproots this diseases. There in no vaccine available till date against this pandemic disease. Ayurveda mainly focuses on prevention of diseases alongwith its total cure. Rajyakshma Vyadhi is MadhyamMarga Roga as per Ayurveda. It shows many symptoms such as Kasa, Shwasa etc. By overall view of Covid 19, shows its resemblance with Rajyakshma Vyadhi described in Ayurveda. Vasavaleha is a Kalpa which is described in Rogadhikara of Rajyakshma. It shows Kasahara, Shwashara properties. It consists of Vasa, Pipalli, Madhu and Goghrita. These components shows actions like bronchodilation, antitussive effect and many more other actions. Pipalli shows important Rasayana effect. So in present review, we have tried to focus on role of Vasavaleha in the management of Covid 19. This can be used as preventive as well as adjuvant medication in treating Covid 19. There is need of further clinical research to rule of exact action of Vasavaleha against Covid 19.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.


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