Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: results from the DPV initiative

2015 ◽  
Vol 17 (3) ◽  
pp. 191-198 ◽  
Author(s):  
Katharina Warncke ◽  
Susanne Liptay ◽  
Elke Fröhlich-Reiterer ◽  
Nicole Scheuing ◽  
Martin Schebek ◽  
...  
2005 ◽  
Vol 22 (3) ◽  
pp. 81-85 ◽  
Author(s):  
ME Wallymahmed ◽  
J Pinkney ◽  
S Saunders ◽  
IA MacFarlane

1991 ◽  
Vol 90 (2-3) ◽  
pp. 223
Author(s):  
P WINOCOUR ◽  
P DURRINGTON ◽  
D BHATNAGAR ◽  
A MBEWU ◽  
M ISHOLA ◽  
...  

2004 ◽  
Vol 490 (1-3) ◽  
pp. 159-168 ◽  
Author(s):  
Augustina M.A Brands ◽  
Roy P.C Kessels ◽  
Edward H.F de Haan ◽  
L.Jaap Kappelle ◽  
Geert Jan Biessels

Author(s):  
Stuart Keel ◽  
Catherine Itsiopoulos ◽  
Konstandina Koklanis ◽  
Meri Vukicevic ◽  
Fergus Cameron ◽  
...  

AbstractBackground:The aim of the study was to describe the relationship of retinal arteriolar and venular calibre with vascular risk factors in children and adolescents with type 1 diabetes.Methods:In this hospital-based cross-sectional study, the medical files of 483 children and adolescents with type 1 diabetes were audited to collect retinal images and relevant clinical data. Retinal vascular calibre was measured using standardised protocols.Results:After multivariable adjustments, a vascular risk profile that included: older age, higher serum creatinine, higher systolic blood pressure (SBP), higher body mass index (BMI), abnormal estimated glomerular filtration rate (eGFR), lower high-density lipoproteins (HDL) cholesterol, longer duration of diabetes and higher serum sodium was associated with narrower central retinal artery equivalent (CRAE) (95% CI=−4.10/−0.76, p=0.004). A specific risk profile, including higher total cholesterol level, higher BMI, lower physical activity level, higher HbAConclusions:In summary, these findings support evidence that cardiovascular disease may have its origins early in life. Prospective and/or intervention studies are required to confirm whether the observed associations are involved in the causal pathway for retinal vascular calibre.


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