scholarly journals RELATIONSHIP BETWEEN OBSTRUCTIVE SLEEP APNOEA, OTHER CARDIOVASCULAR RISK FACTORS AND CARDIOVASCULAR DISEASE

Respirology ◽  
2018 ◽  
Vol 23 ◽  
pp. 38-38
2019 ◽  
Vol 154 ◽  
pp. 127-132 ◽  
Author(s):  
Helge Haarmann ◽  
Jennifer Koch ◽  
Nina Bonsch ◽  
Meinhard Mende ◽  
Stefanie Maria Werhahn ◽  
...  

2010 ◽  
Vol 104 (7) ◽  
pp. 1063-1068 ◽  
Author(s):  
Jean-Pierre Laaban ◽  
Line Mounier ◽  
Olivier Roque d'Orbcastel ◽  
Dan Veale ◽  
Jacques Blacher ◽  
...  

2017 ◽  
Vol 39 ◽  
pp. e16-e17 ◽  
Author(s):  
B. De Vega Sánchez ◽  
S.A. Juarros Martínez ◽  
Milagros Del Olmo Chiches ◽  
C. Disdier Vicente ◽  
E. González Sarmiento

Author(s):  
Paweł Gać ◽  
Dominika Urbanik ◽  
Piotr Macek ◽  
Helena Martynowicz ◽  
Grzegorz Mazur ◽  
...  

2021 ◽  
Vol 8 (1) ◽  
pp. e000848
Author(s):  
Mark Hwang ◽  
Kevin Zhang ◽  
Mahesh Nagappa ◽  
Aparna Saripella ◽  
Marina Englesakis ◽  
...  

IntroductionObstructive sleep apnoea (OSA) is highly prevalent in patients with cardiovascular risk factors and is associated with increased morbidity and mortality. This review presents the predictive parameters of the STOP-Bang questionnaire as a screening tool for OSA in this population.MethodsA search of databases was performed. The inclusion criteria were: (1) use of the STOP-Bang questionnaire to screen for OSA in adults (>18 years) with cardiovascular risk factors; (2) polysomnography or home sleep apnoea testing performed as a reference standard; (3) OSA defined by either Apnoea–Hypopnoea Index (AHI) or Respiratory Disturbance Index; and (4) data on predictive parameters of the STOP-Bang questionnaire. A random-effects model was used to obtain pooled predictive parameters of the STOP-Bang questionnaire.ResultsThe literature search resulted in 3888 articles, of which 9 papers met the inclusion criteria, involving 1894 patients. The average age of the included patients was 58±13 years with body mass index (BMI) of 30±6 kg/m2, and 64% were male. The STOP-Bang questionnaire has a sensitivity of 89.1%, 90.7% and 93.9% to screen for all (AHI ≥5), moderate-to-severe (AHI ≥15) and severe (AHI≥30) OSA, respectively. The specificity was 32.3%, 22.5% and 18.3% and the area under the curve (AUC) was 0.86, 0.65 and 0.52 for all, moderate-to-severe and severe OSA, respectively.ConclusionThe STOP-Bang questionnaire is an effective tool to screen for OSA (AHI≥5) with AUC of 0.86 in patients with cardiovascular risk factors.


2019 ◽  
Vol 70 (10) ◽  
pp. 3582-3586

Obstructive sleep apnoea syndrome (OSAS) increases the risk cardiovascular events regardless of the presence of previous cardiovascular disease. As both OSAS and coronary heart disease (CHD) have same risk factors it’s often difficult to quantify the proportion of each risk factor in developing cardiac events. The aim of this study was to evaluate the 10-year risk of developing a coronary heart disease (CHD) event or stroke in newly diagnosed OSAS patients. 65 patients diagnosed with OSAS over a period of four months in Oradea Sleep Laboratory were included. Demographic characteristics, anthropometric parameters, clinical and biochemical data, sleep disorder and daytime sleepiness assessment, results of polysomnography were collected in all patients. In 55 selected patients by age range from 34 to 74 years old, cardiovascular risk was assessed using Framingham score calculator. Statistical analysis was performed using SPSS-PC version 7.5 and Stata 10.The estimated 10-years risk of a CHD event was 18.97% (± 9.67) in all cases. It was higher in men (22.17% ± 9.24) compare to women (12.39% ± 6.92) and it was not significantly different by stages of OSAS severity (20.58% ±9.41 in patients with severe OSAS versus 15.4% in mild OSAS), suggesting that apnea hypopnea index is not a major confounding factor. Desaturation of oxygen is a better outcome to define the relation between OSAS and cardiovascular diseases. OSAS and cardiovascular risk factors increased risk for future adverse cardiovascular events related to the severity of oxygen desaturation. Keywords: obstructive sleep apnoea syndrome, cardiovascular events, risk factors, oxygen desaturation


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