Detection of antibodies to duck tembusu virus in human population with or without the history of contact with ducks

Author(s):  
Rojjanaporn Pulmanausahakul ◽  
Kunjimas Ketsuwan ◽  
Thitigun Jaimipuk ◽  
Duncan R. Smith ◽  
Prasert Auewarakul ◽  
...  
2021 ◽  
pp. 101048
Author(s):  
Tianxu Li ◽  
Xiaofang Hu ◽  
Tingting Zhang ◽  
Xingdong Song ◽  
Huihui Zhang ◽  
...  

2013 ◽  
Vol 10 (1) ◽  
pp. 260 ◽  
Author(s):  
Shuang Li ◽  
Xiaoxia Li ◽  
Lijiao Zhang ◽  
Yongyue Wang ◽  
Xiuling Yu ◽  
...  

Author(s):  
Diyendo Massilani ◽  
Laurits Skov ◽  
Mateja Hajdinjak ◽  
Byambaa Gunchinsuren ◽  
Damdinsuren Tseveendorj ◽  
...  

AbstractWe present analyses of the genome of a ~34,000-year-old hominin skull cap discovered in the Salkhit Valley in North East Mongolia. We show that this individual was a female member of a modern human population that, following the split between East and West Eurasians, experienced substantial gene flow from West Eurasians. Both she and a 40,000-year-old individual from Tianyuan outside Beijing carried genomic segments of Denisovan ancestry. These segments derive from the same Denisovan admixture event(s) that contributed to present-day mainland Asians but are distinct from the Denisovan DNA segments in present-day Papuans and Aboriginal Australians.


Acta Tropica ◽  
2022 ◽  
pp. 106310
Author(s):  
Chalida Sri-in ◽  
Aunyaratana Thontiravong ◽  
Lyric C. Bartholomay ◽  
Sonthaya Tiawsirisup

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Xuejing Sun ◽  
Enxue Liu ◽  
Adeela Iqbal ◽  
Taozhi Wang ◽  
Xindong Wang ◽  
...  

Viruses ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 238 ◽  
Author(s):  
Xiao Ren ◽  
Xiaolei Wang ◽  
Shan Zhang ◽  
Xintao Gao ◽  
Lichun Fang ◽  
...  

Duck Tembusu virus (DTMUV) is an emerging pathogenic flavivirus responsible for massive economic losses in the duck industry. However, commercially inactivated DTMUV vaccines have been ineffective at inducing protective immunity in ducks. The widely used adjuvant cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) reportedly improve humoral and cellular immunities in animal models. However, its effectiveness in DTMUV vaccines requires validation. Here, we assessed the protective efficacy of pUC18-CpG as an adjuvant in an inactivated live DTMUV vaccine in ducks. Our results revealed that the serum hemagglutination inhibition (HI) antibody titers, positive rates of anti-DTMUV antibodies, the concentration of serum cytokines, and protection efficacy were significantly increased in ducks immunized with pUC18-CpG compared to that in the control group. Moreover, ducks immunized with a full vaccine dose containing a half dose of antigen supplemented with 40 μg of pUC18-CpG exhibited the most potent responses. This study suggests that pUC18-CpG is a promising adjuvant against DTMUV, which might prove effective in treating other viral diseases in waterfowl.


2019 ◽  
Vol 231 ◽  
pp. 218-225 ◽  
Author(s):  
Dalin He ◽  
Xin Zhang ◽  
Lin Chen ◽  
Yi Tang ◽  
Youxiang Diao

Sign in / Sign up

Export Citation Format

Share Document