Expression of a high activity diacylglycerol acetyltransferase results in enhanced synthesis of acetyl‐TAG in camelina seed oil

2021 ◽  
Author(s):  
Linah Alkotami ◽  
Catherine Kornacki ◽  
Shahna Campbell ◽  
Gary McIntosh ◽  
Cole Wilson ◽  
...  
Keyword(s):  
Seed Oil ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 589-600
Author(s):  
R. Pathak ◽  
M. Mohsin ◽  
S. P. S Mehta

The present study was aimed to analyze the physicochemical properties of Camelina sativa L. seed oil in order to identify its utilization as a primary feedstock for biofuel production. Efforts were also made to identify and quantify the amount of α- tocopherols in Camelina seed oil and evaluated in vitro antioxidant potential of Camelina sativa seed oil and were compared with α–tocopherol standard. Physicochemical properties such as oil yield content (36.66 %), less acid value (5.39 mg KOH/g) make it a prominent feedstock for biodiesel production.  Saponification value (182.66 mg KOH/g) also makes this oil useful in soap and cosmetic industries. To check in vitro antioxidant potential of Camelina seed oil H2O2, DPPH and ABTS were used as free radical inducers. Oil showed remarkable inhibition potential of trapping these free radicals. Tocopherol content was analyzed through HPTLC. Camelina sativa seed oil was found to contain 59.34 mg/100 g of tocopherol content. It is evident from this study that Camelina oil has high antioxidant potential and there is no need to add other antioxidant substances in the products formed by using Camelina sativa seed oil.


2018 ◽  
Vol 16 (4) ◽  
pp. 926-938 ◽  
Author(s):  
Xiao-Hong Yu ◽  
Rebecca E. Cahoon ◽  
Patrick J. Horn ◽  
Hai Shi ◽  
Richa R. Prakash ◽  
...  

2017 ◽  
Vol 31 (5) ◽  
pp. 5629-5634 ◽  
Author(s):  
Ke Zhang ◽  
Zhenglin Tan ◽  
Chengci Chen ◽  
Xiuzhi Susan Sun ◽  
Donghai Wang

1880 ◽  
Vol 10 (243supp) ◽  
pp. 3874-3874
Author(s):  
Benjamin Nickels

Planta Medica ◽  
2015 ◽  
Vol 81 (05) ◽  
Author(s):  
V Shulaev ◽  
MD Jones ◽  
D Sturtevant ◽  
PJ Horn ◽  
J Crossley ◽  
...  

2001 ◽  
Vol 40 (06) ◽  
pp. 215-220 ◽  
Author(s):  
S. Bielack ◽  
S. Flege ◽  
J. Eckardt ◽  
J. Sciuk ◽  
H. Jürgens ◽  
...  

Summary Purpose: Despite highly efficacious chemotherapy, patients with osteosarcomas still have a poor prognosis if adequate surgical control cannot be obtained. These patients may benefit from therapy with radiolabeled phosphonates. Patients and Methods: Six patients (three male, three female; seven to 41 years) with unresectable primary osteosarcoma (n = 3) or unresectable recurrent sites of osteosarcomas (n = 3) were treated with high-activity of Sm-153-EDTMP (150 MBq/kg BW). In all patients autologous peripheral blood stem cells had been collected before Sm-153-EDTMP therapy. Results: No immediate adverse reactions were observed in the patients. In one patient bone pain increased during the first 48 hrs after therapy. Three patients received pain relief. Autologous peripheral blood stem cell reinfusion was performed on day +12 to +27 in all patients to overcome potentially irreversible damage to the hematopoietic stem cells. In three patient external radiotherapy of the primary tumor site was performed after Sm-153-EDTMP therapy and in two of them polychemotherapy was continued. Thirty-six months later one of these patients is still free of progression. Two further patients are still alive. However, they have developed new metastases. The three patients who had no accompanying external radiotherapy, all died of disease progression five to 20 months after therapy. Conclusion: These preliminary results show that high-dose Sm-153-EDTMP therapy is feasible and warrants further evaluation of efficacy. The combination with external radiation and polychemotherapy seems to be most promising. Although osteosarcoma is believed to be relatively radioresistant, the total focal dose achieved may delay local progression or even achieve permanent local tumor control in patients with surgically inaccessible primary or relapsing tumors.


1975 ◽  
Vol 34 (02) ◽  
pp. 409-418 ◽  
Author(s):  
I. M Nilsson ◽  
S.-E Bergentz ◽  
U Hedner ◽  
K Kullenberg

SummaryGastric juice from 15 normals, 20 patients with gastric ulcer and 4 patients with erosive haemorrhagic gastroduodenitis was investigated in respect of its activity on unheated and heated fibrin plates and its content of FDP and plasminogen or plasmin with immunochemical methods. Gastric juice from normals showed no activity on unheated and heated fibrin plates, and no FDP or plasminogen could be demonstrated. In the patients with gastric ulcer the gastric juice showed little or no fibrinolytic activity on fibrin plates except in 2, who had regurgitation of duodenal juice and neutral pH of the juice. These patients had equally high activity on heated as on unheated plates and no plasmin could be demonstrated. It was shown that this activity was not due to fibrinolysis, but to non-specific proteolytic activity (probably trypsin). The patients with erosive haemorrhagic gastroduodenitis exhibited quite a different picture. The gastric juice from these patients showed extremely high activity on fibrin plates, the activity was higher on unheated than on heated plates. The activity was inhibited in vitro by addition of EACA and in vivo after administration of AMCA. The occurrence of plasmin could be demonstrated directly immunologically in the gastric juice. By comparison of plasmin and trypsin in various assays it could further be proved that the gastric juice in these cases contained plasminogen activator and plasmin. The patients with erosive haemorrhagic gastroduodenitis showed no increase in fibrinolysis in the blood, but low values for plasminogen and α2M, and the serum contained FDP. These findings in the blood and gastric juice were interpreted as signs of local fibrinolysis in the stomach and duodenum. There is reason to assume that this gastric fibrinolysis contributes substantially to the bleeding tendency. The effect of administration of AMCA on fibrinolytic activity and the haemorrhage lends support to the assumption of such a mechanism.


1979 ◽  
Vol 42 (05) ◽  
pp. 1452-1459 ◽  
Author(s):  
Robert H Yue ◽  
Toby Starr ◽  
Menard M Gertler

SummaryCommercial porcine heparin can be separated into three distinct subtractions by using DEAE-cellulose chromatography and a stepped salt gradient. Gram quantities of heparin can be fractionated by this technique. All three heparin subtractions can accelerate the inhibition of thrombin by antithrombin III with different efficiency. The specific activities of the high activity heparin, intermediate activity heparin and low activity heparin are 228 units/mg, 142 units/mg and 95 units/mg, respectively. Both the uronic acid content and the quantity of N-SO4 for all three heparin subfractions have been evaluated. The high activity heparin has the lowest uronic acid and N-SO4 content. The successful separation of commercial heparin into three distinct subfractions by means of ion-exchange chromatography suggests that the net charge on these three heparin components will serve as a model system in the elucidation of the structure and activity relationship to the biological function of heparin.


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