Effect of peritoneal lavage on bacterial isolates in 40 dogs with confirmed septic peritonitis

ABSTRACT Septic peritonitis is a common, life-threatening condition encountered in dogs and cats. Efficacy of peritoneal lavage has not been proven in veterinary studies. Our objective was to evaluate differences in bacterial identity and susceptibility in samples obtained pre- and postlavage in animals who underwent laparotomy for treatment of septic peritonitis and to assess the effect of empirical antimicrobial selection on survival. Culture samples were collected from the peritoneal surface pre- and postlavage from dogs and cats treated surgically for septic peritonitis. Culture results were compared for each patient with regard to bacterial isolates and bacterial susceptibility profiles. Survival to discharge was evaluated. Microbial growth occurred in at least one culture in 88.6% of patients. There was no significant difference in bacterial isolates or susceptibility profiles pre- versus postlavage. Positive culture pre- or postlavage and appropriate antimicrobial selection did not significantly affect survival. For individual animals, culture results differed between pre- and postlavage samples, although no definitive effect of peritoneal lavage was seen for the population as a whole. Antimicrobials most commonly effective against isolates were Cefotaxime, Ceftazidime, and Imipenem. If prompt surgical source control is employed, antibiotic choice may not affect clinical outcome.

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Peritoneallavage bei septischer Peritonitis des Hundes

Tierärztliche Praxis Ausgabe K Kleintiere / Heimtiere ◽

10.1055/a-1085-5532 ◽

2020 ◽

Vol 48 (01) ◽

pp. 57-58

Author(s):

Daniela Simon Betz

Keyword(s):

Peritoneal Lavage ◽

Bacterial Isolates ◽

Septic Peritonitis

Marshall H, Sinnott-Stutzman V, Ewing P et al. Effect of peritoneal lavage on bacterial isolates in 40 dogs with confirmed septic peritonitis. J Vet Emerg Crit Care 2019; 29 (6): 635–642 Septische Peritonitis (SP) ist eine Infektion der Peritonealhöhle, die häufig durch eine Ruptur im Bereich des Gastrointestinal-, Hepatobiliär- oder Urogenitaltrakts bedingt ist. In der Humanmedizin gilt eine Peritoneallavage (PL) bei SP als nicht unumstritten, stellt dennoch eine häufig angewandte Behandlungsmethode dar. Bei Hunden mit SP liegen nur wenige Erkenntnisse zur Zusammensetzung des bakteriellen Spektrums und der Antibiotika-Resistenzlage bzw. deren Veränderung im Verlauf einer PL vor. Ziel dieser Studie war, die mikrobiologische Zusammensetzung, die Antibiotikasensitivität und das Antibiotika-Resistenzmuster der Bakterien in der Bauchhöhlenflüssigkeit von Hunden mit SP vor und nach einer PL zu untersuchen.

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EFFICACY OF PERITONEAL LAVAGE AND INTRAPERITONEAL INJECTION WITH CEFTRIAXONE COMBINATION WITH NEPHRECTOMY IN RENAL ABSCESS AND SEPTIC PERITONITIS FROM PROTEUS MIRABILIS IN A DOG

Journal of Bio Innovation ◽

10.46344/jbino.2020.v09i05.11 ◽

2020 ◽

Vol 9 (5) ◽

pp. 764-770

Author(s):

Piyabongkarn Damrongdej ◽

Phalitakul Sukanya

Keyword(s):

Proteus Mirabilis ◽

Intraperitoneal Injection ◽

Peritoneal Lavage ◽

Renal Abscess ◽

Septic Peritonitis

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In Adult Horses With Septic Peritonitis, Does Peritoneal Lavage Combined With Antibiotic Therapy Compared to Antibiotic Therapy Alone Improve Survival Rates?

Veterinary Evidence ◽

10.18849/ve.v2i4.135 ◽

2017 ◽

Vol 2 (4) ◽

Author(s):

Sarah Scott Smith

Keyword(s):

Clinical Practice ◽

Open Access ◽

Antibiotic Therapy ◽

Peritoneal Lavage ◽

Survival Rates ◽

Quality Of Evidence ◽

Antiseptic Solution ◽

Septic Peritonitis

The quality of evidence in equids is insufficient to direct clinical practice aside from the following:The use of antiseptic solution to lavage the abdomen causes inflammation and is detrimental to the patient.For peritonitis caused by Actinobacillus equuli, treatment with antibiotics alone may be sufficient. A variety of antibiotics were used in the two reported studies. <img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed" />

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Adaptive Reactions of Winter Wheat (Triticum aestivum L.) Affected by Eyespot Causal Agent under the Action of Bacillus subtilis Bacterial Isolates

Mikrobiolohichnyi Zhurnal ◽

10.15407/microbiolj81.01.049 ◽

2019 ◽

Vol 81 (1) ◽

pp. 49-60

Author(s):

L.M. Batsmanova ◽

◽

Y.M. Pysmenna ◽

T.O. Kondratiuk ◽

N.Y. Taran ◽

...

Keyword(s):

Triticum Aestivum ◽

Bacillus Subtilis ◽

Winter Wheat ◽

Triticum Aestivum L ◽

Causal Agent ◽

Bacterial Isolates ◽

Adaptive Reactions

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Effects of Saline and Other Peritoneal Lavage Solutions on the Morphology and Function of in Vitro Mesothelial Cells

Polish Journal of Surgery ◽

10.2478/v10035-007-0084-9 ◽

2007 ◽

Vol 79 (8) ◽

Author(s):

Marek Winckiewicz ◽

Alicja Połubińska ◽

Ryszard Staniszewski ◽

Andrzej Bręborowicz

Keyword(s):

Peritoneal Lavage ◽

Mesothelial Cells ◽

And Function

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Identification Pseudomonas aeruginosa by OprD Gene for Differentiation from Other Pseudomonas Species that Isolated from Clinical Samples

International Journal of Drug Delivery Technology ◽

10.25258/ijddt.9.1.8 ◽

2019 ◽

Vol 9 (01) ◽

pp. 46-50

Author(s):

Ashwak B Al-Hashimy ◽

Huda S Alagely ◽

Akeel K Albuaji ◽

Khalid R Majeed

Keyword(s):

Pseudomonas Aeruginosa ◽

General Hospital ◽

Culture Media ◽

Final Diagnosis ◽

Clinical Samples ◽

Bacterial Isolates ◽

Molecular Method ◽

Biochemical Tests ◽

Pseudomonas Species ◽

Specific Sequences

The present study included the collection of 100 samples from various clinical sources for investigating the presence of P. aeruginosa in those sources, the samples have been collected from some hospitals in Baghdad and Hillah city (Al-qassim General Hospital, ,Al-hillah teaching hospital,and Al-hashimya General hospital ) which included wounds, burns, ear and sputum infections. The study was carried out through October 2017 till the end of March 2018. The samples were identified based on the morphological and microscopically characteristics of the colonies when they were culturing or number of culture media as well as biochemical tests, molecular identification were also used as a final diagnostic test for isolates that were positive as they belong to P.aeruginosa bacteria during previous tests based on the OprD gene which has specific sequences for P.aeruginosa bacteria as a detection gene and also consider as virulence factor so it have a synonyms mechanism to antibiotic resistance . The results of the final diagnosis showed that 38 isolates belong to target bacteria were distributed as 18 of burns, 11 isolates of wounds, 6 isolates of ear infection and 3 isolates of sputum, The examination of the sensitivity of all bacterial isolates was done for elected 38 isolation towards the 9 antibiotic by a Bauer - Kirby and the isolates were resistant for a number of antibiotics used such as Ciprofloxacin 65.7%, Norflaxacin 71%, Imipenem 63.1% Meropenem 68.4%, Gentamicin 65.7%, Amikacin 26.3%, Cefepime 68.4%, Ceftazidime 65.7% and Piperacillin 57.8%.Molecular method , All isolates (38) of P. aeruginosa positive for the diagnostic special gene (OprD) genes (100%).

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