Deformation Behavior of Magnesium Extrusions With Strong Basal Texture: Experiments and Modeling

2013 ◽  
Vol 80 (6) ◽  
Author(s):  
Dirk Mohr ◽  
Marc-Antoine Chevin ◽  
Lars Greve

Reverse tension-compression and compression-tension experiments are performed on an extruded AZ31B magnesium sheets using a newly-developed antibuckling device. In addition, combined tension and shear experiments are performed to investigate the material response to multiaxial loading. A constitutive model is proposed which makes use of a single crystal approach to describe the dominant twinning and detwinning response, while a quadratic anisotropic yield function is employed to model the slip-dominated material response. The model accounts for the characteristic tension-compression asymmetry in the hardening mechanisms. Both the convex-up shaped stress-strain response under twinning and concave-down shaped response for slip-dominated behavior are predicted accurately. Furthermore, the effect of latent hardening among slip and twinning systems is taken into account. Due to strong simplifications regarding the kinematics of twinning, the model is computationally efficient and suitable for large scale structural computations.

Author(s):  
B. Aparna ◽  
S. Madhavi ◽  
G. Mounika ◽  
P. Avinash ◽  
S. Chakravarthi

We propose a new design for large-scale multimedia content protection systems. Our design leverages cloud infrastructures to provide cost efficiency, rapid deployment, scalability, and elasticity to accommodate varying workloads. The proposed system can be used to protect different multimedia content types, including videos, images, audio clips, songs, and music clips. The system can be deployed on private and/or public clouds. Our system has two novel components: (i) method to create signatures of videos, and (ii) distributed matching engine for multimedia objects. The signature method creates robust and representative signatures of videos that capture the depth signals in these videos and it is computationally efficient to compute and compare as well as it requires small storage. The distributed matching engine achieves high scalability and it is designed to support different multimedia objects. We implemented the proposed system and deployed it on two clouds: Amazon cloud and our private cloud. Our experiments with more than 11,000 videos and 1 million images show the high accuracy and scalability of the proposed system. In addition, we compared our system to the protection system used by YouTube and our results show that the YouTube protection system fails to detect most copies of videos, while our system detects more than 98% of them.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Hongyi Zhang ◽  
Xiaowei Zhan ◽  
Bo Li

AbstractSimilarity in T-cell receptor (TCR) sequences implies shared antigen specificity between receptors, and could be used to discover novel therapeutic targets. However, existing methods that cluster T-cell receptor sequences by similarity are computationally inefficient, making them impractical to use on the ever-expanding datasets of the immune repertoire. Here, we developed GIANA (Geometric Isometry-based TCR AligNment Algorithm) a computationally efficient tool for this task that provides the same level of clustering specificity as TCRdist at 600 times its speed, and without sacrificing accuracy. GIANA also allows the rapid query of large reference cohorts within minutes. Using GIANA to cluster large-scale TCR datasets provides candidate disease-specific receptors, and provides a new solution to repertoire classification. Querying unseen TCR-seq samples against an existing reference differentiates samples from patients across various cohorts associated with cancer, infectious and autoimmune disease. Our results demonstrate how GIANA could be used as the basis for a TCR-based non-invasive multi-disease diagnostic platform.


Author(s):  
Mahdi Esmaily Moghadam ◽  
Yuri Bazilevs ◽  
Tain-Yen Hsia ◽  
Alison Marsden

A closed-loop lumped parameter network (LPN) coupled to a 3D domain is a powerful tool that can be used to model the global dynamics of the circulatory system. Coupling a 0D LPN to a 3D CFD domain is a numerically challenging problem, often associated with instabilities, extra computational cost, and loss of modularity. A computationally efficient finite element framework has been recently proposed that achieves numerical stability without sacrificing modularity [1]. This type of coupling introduces new challenges in the linear algebraic equation solver (LS), producing an strong coupling between flow and pressure that leads to an ill-conditioned tangent matrix. In this paper we exploit this strong coupling to obtain a novel and efficient algorithm for the linear solver (LS). We illustrate the efficiency of this method on several large-scale cardiovascular blood flow simulation problems.


Author(s):  
Leigh McCue

Abstract The purpose of this work is to develop a computationally efficient model of viral spread that can be utilized to better understand influences of stochastic factors on a large-scale system - such as the air traffic network. A particle-based model of passengers and seats aboard a single-cabin 737-800 is developed for use as a demonstration of concept on tracking the propagation of a virus through the aircraft's passenger compartment over multiple flights. The model is sufficiently computationally efficient so as to be viable for Monte Carlo simulation to capture various stochastic effects, such as number of passengers, number of initially sick passengers, seating locations of passengers, and baseline health of each passenger. The computational tool is then exercised in demonstration for assessing risk mitigation of intervention strategies, such as passenger-driven cleaning of seating environments and elimination of middle seating.


Author(s):  
Feng Jie Zheng ◽  
Fu Zheng Qu ◽  
Xue Guan Song

Reservoir-pipe-valve (RPV) systems are widely used in many industrial process. The pressure in an RPV system plays an important role in the safe operation of the system, especially during the sudden operation such as rapid valve opening/closing. To investigate the pressure especially the pressure fluctuation in an RPV system, a multidimensional and multiscale model combining the method of characteristics (MOC) and computational fluid dynamics (CFD) method is proposed. In the model, the reservoir is modeled by a zero-dimensional virtual point, the pipe is modeled by a one-dimensional MOC, and the valve is modeled by a three-dimensional CFD model. An interface model is used to connect the multidimensional and multiscale model. Based on the model, a transient simulation of the turbulent flow in an RPV system is conducted, in which not only the pressure fluctuation in the pipe but also the detailed pressure distribution in the valve are obtained. The results show that the proposed model is in good agreement with the full CFD model in both large-scale and small-scale spaces. Moreover, the proposed model is more computationally efficient than the CFD model, which provides a feasibility in the analysis of complex RPV system within an affordable computational time.


2021 ◽  
Vol 11 (12) ◽  
pp. 1556
Author(s):  
Saber Meamardoost ◽  
Mahasweta Bhattacharya ◽  
Eun Jung Hwang ◽  
Takaki Komiyama ◽  
Claudia Mewes ◽  
...  

The inference of neuronal connectome from large-scale neuronal activity recordings, such as two-photon Calcium imaging, represents an active area of research in computational neuroscience. In this work, we developed FARCI (Fast and Robust Connectome Inference), a MATLAB package for neuronal connectome inference from high-dimensional two-photon Calcium fluorescence data. We employed partial correlations as a measure of the functional association strength between pairs of neurons to reconstruct a neuronal connectome. We demonstrated using in silico datasets from the Neural Connectomics Challenge (NCC) and those generated using the state-of-the-art simulator of Neural Anatomy and Optimal Microscopy (NAOMi) that FARCI provides an accurate connectome and its performance is robust to network sizes, missing neurons, and noise levels. Moreover, FARCI is computationally efficient and highly scalable to large networks. In comparison with the best performing connectome inference algorithm in the NCC, Generalized Transfer Entropy (GTE), and Fluorescence Single Neuron and Network Analysis Package (FluoroSNNAP), FARCI produces more accurate networks over different network sizes, while providing significantly better computational speed and scaling.


2019 ◽  
Vol 141 (5) ◽  
Author(s):  
Feng Jie Zheng ◽  
Chao Yong Zong ◽  
William Dempster ◽  
Fu Zheng Qu ◽  
Xue Guan Song

Reservoir-pipe-valve (RPV) systems are widely used in many industrial processes. The pressure in an RPV system plays an important role in the safe operation of the system, especially during the sudden operations such as rapid valve opening or closing. To investigate the pressure response, with particular interest in the pressure fluctuations in an RPV system, a multidimensional and multiscale model combining the method of characteristics (MOC) and computational fluid dynamics (CFD) method is proposed. In the model, the reservoir is modeled as a zero-dimensional virtual point, the pipe is modeled as a one-dimensional system using the MOC, and the valve is modeled using a three-dimensional CFD model. An interface model is used to connect the multidimensional and multiscale model. Based on the model, a transient simulation of the turbulent flow in an RPV system is conducted in which not only the pressure fluctuation in the pipe but also the detailed pressure distribution in the valve is obtained. The results show that the proposed model is in good agreement when compared with a high fidelity CFD model used to represent both large-scale and small-scale spaces. As expected, the proposed model is significantly more computationally efficient than the CFD model. This demonstrates the feasibility of analyzing complex RPV systems within an affordable computational time.


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