Experimental Investigation of Collagen Waviness and Orientation in Adventitia of Common Carotid Arteries of Rabbits

2012 ◽  
Author(s):  
Aristotelis Agianniotis ◽  
Nikos Stergiopulos
Keyword(s):  
Mechanical Properties ◽  
Structural Organization ◽  
Collagen Fiber ◽  
Carotid Arteries ◽  
Collagen Fibers ◽  
Angular Dispersion ◽  
Fluorescent Marker ◽  
Outermost Layer ◽  
Common Carotid Arteries ◽  
Fiber Organization

The adventitia is the outermost layer of blood vessels and its mechanical properties are determined by the organization of collagen fibers in this layer. The waviness and the angular dispersion characterize the collagen fiber organization. Previous studies were mainly conducted on loaded and chemically fixed vessels, which could modify the structural organization [1]. We have combined fluorescent marker with confocal microscopy and image analysis to quantify the waviness and angular distribution of collagen fibers, and determine the correlation between the waviness distribution of fibers and their main orientation in the adventitia of rabbit common carotid arteries at their zero-stress state.

India Ink Pinprick Experiments on Surface Organization of Cricoarytenoid Joints

1986 ◽  
Vol 29 (4) ◽  
pp. 544-548 ◽  
Author(s):  
Joel C. Kahane ◽  
Alice R. Kahn
Keyword(s):  
Articular Cartilage ◽  
Collagen Fiber ◽  
Collagen Fibers ◽  
Articular Surfaces ◽  
India Ink ◽  
Age Related ◽  
Cricoarytenoid Joint ◽  
Mechanical Factors ◽  
Fiber Organization

Collagen fiber organization in the articular surfaces of the cricoarytenoid joint (CAJ) was studied using a pinpricking technique used in biomechanical research in orthopedics. Four male human formalin preserved specimens (3 months to 20 years) and 6 male freshly autopsied specimens (19 to 30 yrs) were studied. Specimens were dissected using the stereomicroscope. Distinctive patterns of articular cartilage slits reflect the orientation of collagen fibers in the cricoid and arytenoid articular surfaces. The orientation of the collagen fibers reinforces the articular surfaces along the principle path of CAJ motion. No age related differences were found. This suggests that the orientation of collagen fibers in the CAJ articular surfaces is prenatally determined rather than significantly influenced by postnatal mechanical factors.

Collagen fiber organization is related to mechanical properties and remodeling in equine bone. A comparsion of two methods

1996 ◽  
Vol 29 (12) ◽  
pp. 1515-1521 ◽  
Author(s):  
R.B. Martin ◽  
S.T. Lau ◽  
P.V. Mathews ◽  
V.A. Gibson ◽  
S.M. Stover
Keyword(s):  
Mechanical Properties ◽  
Collagen Fiber ◽  
Fiber Organization ◽  
Equine Bone

Relationship Between Mechanical Properties and Collagen Structure of Closed and Open Wounds

1988 ◽  
Vol 110 (4) ◽  
pp. 352-356 ◽  
Author(s):  
Charles J. Doillon ◽  
Michael G. Dunn ◽  
Frederick H. Silver
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Ultimate Tensile Strength ◽  
Collagen Fiber ◽  
Fiber Diameter ◽  
Normal Skin ◽  
Collagen Fibers ◽  
Collagen Structure ◽  
Collagen Network

Mechanical properties and collagen structure of excisional wounds left open are compared with wounds closed by clips. In both wound models, collagen fiber diameter increases with time post-wounding and is related to tensile strength. Clipped wounds show a higher ultimate tensile strength and tangent modulus compared with open wounds. In clipped wounds, newly deposited collagen appears as a biaxially oriented network as observed in normal skin. In open wounds a delay in the organization of the collagen network is observed and parallel wavy-shaped ribbons of collagen fibers are deposited. At long term, the high extensibility observed in open wounds may be due to the sliding of ribbons of collagen fibers past each other.

Study on the Preparation and Properties of Collagen Fiber- Polyurethane Composite Film

2011 ◽  
Vol 239-242 ◽  
pp. 3211-3215 ◽  
Author(s):  
Xing Yuan Ma ◽  
Yong Sheng Guo ◽  
Ling Yun Lu ◽  
Kun Jiang
Keyword(s):  
Mechanical Properties ◽  
Phase Separation ◽  
Water Vapor ◽  
Composite Film ◽  
Porous Structure ◽  
Collagen Fiber ◽  
Water Vapor Permeability ◽  
Collagen Fibers ◽  
Polymer Materials ◽  
Vapor Permeability

Chrome-tanned collagen fiber is the major solid waste of leather industry which is difficult to biological degradation and would caused serious pollution to the environment. However, the collagen fibers as a natural biological polymer materials, has unique properties of surface reactivity that the other polymer materials are not available. In this paper, the composite film of chrome-tanned collagen fiber- polyurethane (PU) were prepared is owing to H2O induced phase separation, and measured water vapor permeability, permeability, mechanical properties and microstructure. The results showed that the composite film of chrome-tanned collagen fiber-PU have continuous porous structure, which can improve the water vapor permeability and permeability of film, but reduce the mechanical properties of film. Thermal gravimetric analysis (TGA) showed that the thermal effect of collagen fiber and PU did not change significantly, so composite of collagen fiber and polyurethane by H2O induced phase separation belongs to physical process. The result demonstrates that this composite film has continuous porous structure, and collagen fibers with unique properties of surface reactions, so this material have potential applications in many fields.

scholarly journals Flow-Induced Changes in Dimensions and Mechanical Properties of Rabbit Common Carotid Arteries

2005 ◽  
Vol 48 (4) ◽  
pp. 477-483 ◽  
Author(s):  
Takeo MATSUMOTO ◽  
Eijiro OKUMURA ◽  
Takahiro SHIRONO ◽  
Eiketsu SHO ◽  
Hirotake MASUDA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Carotid Arteries ◽  
Induced Changes ◽  
Common Carotid Arteries

Investigation of 3-D mechanical properties of blood vessels using a new in vitro tests system: results on sheep common carotid arteries

2001 ◽  
Vol 48 (4) ◽  
pp. 442-451 ◽  
Author(s):  
W.C.P.M. Blondel ◽  
J. Didelon ◽  
G. Maurice ◽  
J.-P. Carteaux ◽  
Xiong Wang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Blood Vessels ◽  
Carotid Arteries ◽  
In Vitro Tests ◽  
Common Carotid Arteries

scholarly journals Force Spectroscopy of Collagen Fibers to Investigate Their Mechanical Properties and Structural Organization

2004 ◽  
Vol 86 (5) ◽  
pp. 3186-3193 ◽  
Author(s):  
Thomas Gutsmann ◽  
Georg E. Fantner ◽  
Johannes H. Kindt ◽  
Manuela Venturoni ◽  
Signe Danielsen ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Structural Organization ◽  
Force Spectroscopy ◽  
Collagen Fibers

Collagen Fiber Structure Correlates With Mechanical Environment in Healing Myocardial Infarcts

2009 ◽  
Author(s):  
Gregory M. Fomovsky ◽  
Jeffrey W. Holmes
Keyword(s):  
Mechanical Properties ◽  
Ventricular Function ◽  
Rat Model ◽  
Collagen Fiber ◽  
Important Determinant ◽  
Collagen Fibers ◽  
Anisotropic Structure ◽  
Fiber Structure ◽  
Mechanical Environment ◽  
Time Points

Mechanics of healing myocardial infarcts are an important determinant of ventricular function. Large collagen fibers are the major contributors to the mechanical properties of healing scar. It has been suggested that an anisotropic structure, as observed in healing pig scars, may help preserve ventricular function, and that the alignment of collagen fibers could be guided by the regional mechanical environment in the infarct — in pig scars the alignment of collagen fibers was in the direction of greatest stretch [1]. By contrast, in the standard rat model of infarction we found that scars are structurally and mechanically isotropic at all time points in healing [2].

scholarly journals A method to analyze the influence of mechanical strain on dermal collagen morphologies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maximilian Witte ◽  
Michael Rübhausen ◽  
Sören Jaspers ◽  
Horst Wenck ◽  
Frank Fischer
Keyword(s):  
Mechanical Properties ◽  
Collagen Fiber ◽  
Ex Vivo ◽  
Second Harmonic ◽  
Mechanical Strain ◽  
Collagen Fibers ◽  
Collagen Network ◽  
Skin Sample ◽  
Fiber Network ◽  
Dermal Collagen

AbstractCollagen fibers and their orientation play a major role in the mechanical behavior of soft biological tissue such as skin. Here, we present a proof-of-principle study correlating mechanical properties with collagen fiber network morphologies. A dedicated multiphoton stretching device allows for mechanical deformations in combination with a simultaneous analysis of its collagen fiber network by second harmonic generation imaging (SHG). The recently introduced Fiber Image Network Evaluation (FINE) algorithm is used to obtain detailed information about the morphology with regard to fiber families in collagen network images. To demonstrate the potential of our method, we investigate an isotropic and an anisotropic ex-vivo dorsal pig skin sample under quasi-static cyclic stretching and relaxation sequences. Families of collagen fibers are found to form a partially aligned collagen network under strain. We find that the relative force uptake is accomplished in two steps. Firstly, fibers align within their fiber families and, secondly, fiber families orient in the direction of force. The maximum alignment of the collagen fiber network is found to be determined by the largest strain. Isotropic and anisotropic samples reveal a different micro structural behavior under repeated deformation leading to a similar force uptake after two stretching cycles. Our method correlates mechanical properties with morphologies in collagen fiber networks.

The mechanical properties of exposed human common carotid arteries in vivo

1979 ◽  
Vol 74 (5) ◽  
pp. 545-554 ◽  
Author(s):  
R. Busse ◽  
R. D. Bauer ◽  
A. Schabert ◽  
Y. Summa ◽  
P. Bumm ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Carotid Arteries ◽  
Common Carotid Arteries
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