Label-free optical spectroscopy techniques for targeted, real time and informed in situ cancer diagnosis (Conference Presentation)

2018 ◽  
Author(s):  
Frédéric Leblond
Keyword(s):  
Real Time ◽  
Optical Spectroscopy ◽  
Cancer Diagnosis ◽  
Label Free

Directly monitoring the active sites of charge transfer in heterocycles in situ and in real time

2019 ◽  
Vol 55 (4) ◽  
pp. 541-544 ◽  
Author(s):  
Shuji Ye ◽  
Junjun Tan ◽  
Kangzhen Tian ◽  
Chuanzhao Li ◽  
Jiahui Zhang ◽  
...  
Keyword(s):  
Charge Transfer ◽  
Real Time ◽  
Vibrational Spectroscopy ◽  
Active Sites ◽  
Electronic States ◽  
Sum Frequency Generation ◽  
Vibrational Modes ◽  
Label Free ◽  
Sum Frequency

Coherent degenerate infrared-infrared-visible sum frequency generation vibrational spectroscopy provides a powerful label-free probe for identifying the vibrational modes that are coupled through the electronic states in situ and in real time.

Monitoring the reactivity of Ag nanoparticles for different atmospheres by using in situ and real-time optical spectroscopy

2011 ◽  
Author(s):  
V. Antad ◽  
L. Simonot ◽  
D. Babonneau ◽  
S. Camelio ◽  
F. Pailloux ◽  
...  
Keyword(s):  
Real Time ◽  
Optical Spectroscopy ◽  
Ag Nanoparticles

scholarly journals Cyclodextrin–polysaccharide-based, in situ-gelled system for ocular antifungal delivery

2014 ◽  
Vol 10 ◽  
pp. 2903-2911 ◽  
Author(s):  
Anxo Fernández-Ferreiro ◽  
Noelia Fernández Bargiela ◽  
María Santiago Varela ◽  
Maria Gil Martínez ◽  
Maria Pardo ◽  
...  
Keyword(s):  
Real Time ◽  
Inclusion Complexes ◽  
Gellan Gum ◽  
Effective Control ◽  
Cell Cytotoxicity ◽  
Label Free ◽  
Real Time Monitoring ◽  
Sulfobutyl Ether ◽  
Human Keratocytes

Fluconazole was studied with two different hydrophilic cyclodextrins (hydroxypropyl-β-cyclodextrin (HPBCD) and sulfobutyl ether-β-cyclodextrin (SBECD)) for the formation of inclusion complexes. HPBCD and SBECD showed low cell cytotoxicity in human keratocytes as assessed by the label-free xCELLigence system for real-time monitoring. The fluconazole–HPBCD complex was incorporated into an ion-sensitive ophthalmic gel composed of the natural polysaccharides gellan gum and κ-carrageenan. This system showed good bioadhesive properties and effective control of fluconazole release.

Nanomechanical Microcantilevers for In-Vitro Biomolecular Detection

2007 ◽  
Author(s):  
Kilho Eom ◽  
Tae Yun Kwon ◽  
Jinsung Park ◽  
Sungsoo Na ◽  
Dae Sung Yoon ◽  
...  
Keyword(s):  
Real Time ◽  
Biological Molecules ◽  
Label Free ◽  
Biomolecular Detection ◽  
Label Free Detection ◽  
Detection Of Biomolecules ◽  
Kinetics Of ◽  
Insight Into

Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.

scholarly journals Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy

2017 ◽  
Vol 77 (14) ◽  
pp. 3942-3950 ◽  
Author(s):  
Michael Jermyn ◽  
Jeanne Mercier ◽  
Kelly Aubertin ◽  
Joannie Desroches ◽  
Kirk Urmey ◽  
...  
Keyword(s):  
Optical Spectroscopy ◽  
Label Free ◽  
Accurate Detection
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