Bacterial inactivation in platelet concentrates using ultrashort pulsed laser

2021 ◽  
Author(s):  
Marin Saiga ◽  
Yuki Obara ◽  
Hideki Abe ◽  
Kazuhiko Misawa
Keyword(s):  
Pulsed Laser ◽  
Bacterial Inactivation ◽  
Platelet Concentrates ◽  
Ultrashort Pulsed Laser

Holographic moving picture recording and observation of ultrashort pulsed laser light propagation

2008 ◽  
Vol 36 (Supplement) ◽  
pp. 201-202
Author(s):  
Yasuhiro Awatsuji ◽  
Kenzo Nishio ◽  
Shogo Ura ◽  
Toshihiro Kubota
Keyword(s):  
Light Propagation ◽  
Laser Light ◽  
Pulsed Laser ◽  
Ultrashort Pulsed Laser

scholarly journals Heat impact during laser ablation extraction of mineralised tissue micropillars

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Samuel McPhee ◽  
Alexander Groetsch ◽  
Jonathan D. Shephard ◽  
Uwe Wolfram
Keyword(s):  
Laser Ablation ◽  
Mechanical Testing ◽  
Laser Scanning ◽  
Pulsed Laser ◽  
Temperature Response ◽  
Collagen Fibre ◽  
Pulsed Laser Ablation ◽  
Collagen Molecules ◽  
Ultrashort Pulsed Laser ◽  
The Impact

AbstractThe underlying constraint of ultrashort pulsed laser ablation in both the clinical and micromachining setting is the uncertainty regarding the impact on the composition of material surrounding the ablated region. A heat model representing the laser-tissue interaction was implemented into a finite element suite to assess the cumulative temperature response of bone during ultrashort pulsed laser ablation. As an example, we focus on the extraction of mineralised collagen fibre micropillars. Laser induced heating can cause denaturation of the collagen, resulting in ultrastructural loss which could affect mechanical testing results. Laser parameters were taken from a used micropillar extraction protocol. The laser scanning pattern consisted of 4085 pulses, with a final radial pass being 22 $$\upmu {\text {m}}$$ μ m away from the micropillar. The micropillar temperature was elevated to 70.58 $$^{\circ }{\text {C}}$$ ∘ C , remaining 79.42 $$^{\circ }{\text {C}}$$ ∘ C lower than that of which we interpret as an onset for denaturation. We verified the results by means of Raman microscopy and Energy Dispersive X-ray Microanalysis and found the laser-material interaction had no effect on the collagen molecules or mineral nanocrystals that constitute the micropillars. We, thus, show that ultrashort pulsed laser ablation is a safe and viable tool to fabricate bone specimens for mechanical testing at the micro- and nanoscale and we provide a computational model to efficiently assess this.

scholarly journals Devitrification of thin film Cu-Zr metallic glass via ultrashort pulsed laser annealing

2021 ◽  
pp. 161437
Author(s):  
J. Antonowicz ◽  
P. Zalden ◽  
K. Sokolowski-Tinten ◽  
K. Georgarakis ◽  
R. Minikayev ◽  
...  
Keyword(s):  
Thin Film ◽  
Metallic Glass ◽  
Laser Annealing ◽  
Pulsed Laser ◽  
Pulsed Laser Annealing ◽  
Ultrashort Pulsed Laser
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