Cancer and the microbiota

A host’s microbiota may increase, diminish, or have no effect at all on cancer susceptibility. Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host-microbiota interactions with environmental factors in carcinogenesis, and exploiting such knowledge for cancer diagnosis and treatment are areas of intensive interest. This Review considers how microbes and the microbiota may amplify or mitigate carcinogenesis, responsiveness to cancer therapeutics, and cancer-associated complications.

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Nanoparticles: A New Approach to Upgrade Cancer Diagnosis and Treatment

Nanoscale Research Letters ◽

10.1186/s11671-021-03489-z ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Zhongyang Yu ◽

Lei Gao ◽

Kehan Chen ◽

Wenqiang Zhang ◽

Qihang Zhang ◽

...

Keyword(s):

Cancer Diagnosis ◽

Cancer Therapeutics ◽

Tumor Diagnosis ◽

Diagnosis And Treatment ◽

New Approach ◽

Future Developments ◽

Novel Approach ◽

Feasible Solutions

AbstractTraditional cancer therapeutics have been criticized due to various adverse effects and insufficient damage to targeted tumors. The breakthrough of nanoparticles provides a novel approach for upgrading traditional treatments and diagnosis. Actually, nanoparticles can not only solve the shortcomings of traditional cancer diagnosis and treatment, but also create brand-new perspectives and cutting-edge devices for tumor diagnosis and treatment. However, most of the research about nanoparticles stays in vivo and in vitro stage, and only few clinical researches about nanoparticles have been reported. In this review, we first summarize the current applications of nanoparticles in cancer diagnosis and treatment. After that, we propose the challenges that hinder the clinical applications of NPs and provide feasible solutions in combination with the updated literature in the last two years. At the end, we will provide our opinions on the future developments of NPs in tumor diagnosis and treatment.

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Role of Aquaporins in Cancer Diagnosis and Treatment: A Review

SSRN Electronic Journal ◽

10.2139/ssrn.3628681 ◽

2019 ◽

Author(s):

Mainak Chatterjee ◽

Ramlal A

Keyword(s):

Cancer Diagnosis ◽

Diagnosis And Treatment

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Cancer Therapeutics-Related Cardiovascular Complications. Mechanisms, Diagnosis and Treatment

Current Pharmaceutical Design ◽

10.2174/1381612825666190111101459 ◽

2019 ◽

Vol 24 (37) ◽

pp. 4424-4435 ◽

Cited By ~ 2

Author(s):

Evangelos Oikonomou ◽

Μaria Anastasiou ◽

Gerasimos Siasos ◽

Emmanuel Androulakis ◽

Amanda Psyrri ◽

...

Keyword(s):

Cancer Therapeutics ◽

Cardiovascular Complications ◽

Diagnosis And Treatment

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Cancer Diagnosis and Treatment Guidance: Role of MRI and MRI Probes in the Era of Molecular Imaging

Current Pharmaceutical Biotechnology ◽

10.2174/1389201014666131226105916 ◽

2014 ◽

Vol 14 (8) ◽

pp. 714-722 ◽

Cited By ~ 10

Author(s):

Jingjing Lu ◽

Feng Feng ◽

Zhengyu Jin

Keyword(s):

Molecular Imaging ◽

Cancer Diagnosis ◽

Diagnosis And Treatment

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Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520619666190710121727 ◽

2020 ◽

Vol 20 (11) ◽

pp. 1276-1287 ◽

Cited By ~ 3

Author(s):

Tran Q. Huy ◽

Pham T.M. Huyen ◽

Anh-Tuan Le ◽

Matteo Tonezzer

Keyword(s):

Silver Nanoparticles ◽

Cancer Treatment ◽

Cancer Diagnosis ◽

Essential Role ◽

Review Paper ◽

Diagnosis And Treatment ◽

Antimicrobial Material ◽

Pathogenic Agents ◽

New Generation ◽

Carrier Systems

Background: Silver nanoparticles (AgNPs) are well-known as a promising antimicrobial material; they have been widely used in many commercial products against pathogenic agents. Despite a growing concern regarding the cytotoxicity, AgNPs still have attracted considerable interest worldwide to develop a new generation of diagnostic tool and effective treatment solution for cancer cells. Objective: This paper aims to review the advances of AgNPs applied for cancer diagnosis and treatment. Methods: The database has been collected, screened and analysed through up-to-date scientific articles published from 2007 to May 2019 in peer-reviewed international journals. Results: The findings of the database have been analysed and divided into three parts of the text that deal with AgNPs in cancer diagnosis, their cytotoxicity, and the role as carrier systems for cancer treatment. Thanks to their optical properties, high conductivity and small size, AgNPs have been demonstrated to play an essential role in enhancing signals and sensitivity in various biosensing platforms. Furthermore, AgNPs also can be used directly or developed as a drug delivery system for cancer treatment. Conclusion: The review paper will help readers understand more clearly and systematically the role and advances of AgNPs in cancer diagnosis and treatment.

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Child development at 6 years after maternal cancer diagnosis and treatment during pregnancy

European Journal of Cancer ◽

10.1016/j.ejca.2020.07.004 ◽

2020 ◽

Vol 138 ◽

pp. 57-67 ◽

Cited By ~ 2

Author(s):

Tineke Vandenbroucke ◽

Magali Verheecke ◽

Mathilde van Gerwen ◽

Kristel Van Calsteren ◽

Michael J. Halaska ◽

...

Keyword(s):

Child Development ◽

Cancer Diagnosis ◽

Diagnosis And Treatment

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Microbial Metabolites in Colorectal Cancer: Basic and Clinical Implications

Metabolites ◽

10.3390/metabo11030159 ◽

2021 ◽

Vol 11 (3) ◽

pp. 159

Author(s):

Yao Peng ◽

Yuqiang Nie ◽

Jun Yu ◽

Chi Chun Wong

Keyword(s):

Colorectal Cancer ◽

Gut Microbiota ◽

Cancer Diagnosis ◽

Intestinal Tract ◽

Clinical Applications ◽

Diagnosis And Treatment ◽

Clinical Implications ◽

Microbial Metabolites ◽

Colorectal Tumorigenesis ◽

Technology Studies

Colorectal cancer (CRC) is one of the leading cancers that cause cancer-related deaths worldwide. The gut microbiota has been proved to show relevance with colorectal tumorigenesis through microbial metabolites. By decomposing various dietary residues in the intestinal tract, gut microbiota harvest energy and produce a variety of metabolites to affect the host physiology. However, some of these metabolites are oncogenic factors for CRC. With the advent of metabolomics technology, studies profiling microbiota-derived metabolites have greatly accelerated the progress in our understanding of the host-microbiota metabolism interactions in CRC. In this review, we briefly summarize the present metabolomics techniques in microbial metabolites researches and the mechanisms of microbial metabolites in CRC pathogenesis, furthermore, we discuss the potential clinical applications of microbial metabolites in cancer diagnosis and treatment.

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