Plasma Concentrations of Isoniazid and Rifampin Are Decreased in Adult Pulmonary Tuberculosis Patients with Diabetes Mellitus
2013 ◽
Vol 57
(11)
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pp. 5740-5742
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Keyword(s):
ABSTRACTPlasma isoniazid and rifampin concentrations, but not pyrazinamide and ethambutol concentrations, were decreased by about 50% (P< 0.05) in diabetic pulmonary tuberculosis patients. The prevalences of subnormal plasma isoniazid, rifampin, pyrazinamide, and ethambutol concentrations were 49% or 100% (P< 0.01), 66% or 100% (P< 0.05), 30% or 50% (P= 0.198), and 32% or 21% (P= 0.742) in nondiabetic or diabetic tuberculosis patients, respectively. These data show that plasma concentrations of isoniazid and rifampin were greatly reduced in diabetic tuberculosis patients.
2020 ◽
Vol 9
(2)
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pp. 43
Keyword(s):
2015 ◽
Vol 4
(4)
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pp. 323-329
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Keyword(s):
2018 ◽
Vol 37
(7)
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pp. 1259-1263
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Keyword(s):