Proteomic analysis of plasma in adult active pulmonary tuberculosis patients with diabetes mellitus

ABSTRACTPlasma isoniazid and rifampin concentrations, but not pyrazinamide and ethambutol concentrations, were decreased by about 50% (P< 0.05) in diabetic pulmonary tuberculosis patients. The prevalences of subnormal plasma isoniazid, rifampin, pyrazinamide, and ethambutol concentrations were 49% or 100% (P< 0.01), 66% or 100% (P< 0.05), 30% or 50% (P= 0.198), and 32% or 21% (P= 0.742) in nondiabetic or diabetic tuberculosis patients, respectively. These data show that plasma concentrations of isoniazid and rifampin were greatly reduced in diabetic tuberculosis patients.

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Comparison The Value Of Bta Sputum Between Pulmonary Tuberculosis Patients With Diabetes Mellitus And Pulmonary Tuberculosis Patients Non-Diabetes Mellitus.

Jurnal Kesehatan Islam : Islamic Health Journal ◽

10.33474/jki.v9i2.8869 ◽

2020 ◽

Vol 9 (2) ◽

pp. 43

Author(s):

Bagas Setiawan ◽

Adyan Donasrtin ◽

Lea Maera ◽

Hotimah Masdan Salim

Keyword(s):

Diabetes Mellitus ◽

Pulmonary Tuberculosis ◽

Descriptive Analysis ◽

Secondary Data ◽

Physiological Disorder ◽

Tuberculosis Patients ◽

Pulmonary Tb ◽

Patients With Diabetes ◽

History Of ◽

Ifn Γ

Background & Aims: Tuberculosis (TB) is a health problem. Based on the WHO report in 2016, Indonesia is a developing country with the second largest TB case. One risk factor for pulmonary tuberculosis is having a history of diabetes mellitus disease. The aim of this research is to examine the differences the value of BTA sputum between pulmonary TB patients with diabetes mellitus and pulmonary TB patients non-diabetes mellitus.Methods: This research is descriptive analytic with comparative study. This study uses secondary data in Islamic Jemursari Surabaya Hospital period January - December 2017. The results will be processed using descriptive analysis and Mann-Whitney test with SPSS 25.00 for windows.Results: This research obtained 68 samples consisting of 34 the pulmonary TB non-diabetes mellitus and 34 pulmonary TB with diabetes mellitus. In pulmonary TB patients non-diabetes mellitus most have negative BTA sputum values, while pulmonary TB with diabetes mellitus is positive (+1), so there are differences in the value of BTA sputum with a significance value 0.001 (<0.05).Conclusion: There is a difference in the value of BTA sputum between pulmonary TB patients with diabetes mellitus and pulmonary TB patients non-diabetes mellitus. It caused in patients with diabetes mellitus have immunological abnormalities, especially IFN-γ and pulmonary physiological disorder.

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High magnitude of diabetes mellitus among Active Pulmonary Tuberculosis Patients in Ethiopia

British Journal of Medicine and Medical Research ◽

10.9734/bjmmr/2014/6198 ◽

2013 ◽

Vol 4 (3) ◽

Cited By ~ 1

Keyword(s):

Diabetes Mellitus ◽

Pulmonary Tuberculosis ◽

Tuberculosis Patients ◽

Active Pulmonary Tuberculosis ◽

High Magnitude

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Pulmonary tuberculosis patients with diabetes mellitus have a more severe degree of chest X-ray compared to pulmonary tuberculosis patients without diabetes mellitus

Gaceta Médica de Caracas - Supplement 1 ◽

10.47307/gmc.2021.129.s2.25 ◽

2021 ◽

Vol 129 (s2) ◽

Author(s):

Muhammad Ramzi ◽

Muslim Andala Putra ◽

Mohammad Subkhan

Keyword(s):

Diabetes Mellitus ◽

Pulmonary Tuberculosis ◽

Tuberculosis Patients ◽

Pulmonary Tb ◽

X Ray ◽

Patients With Diabetes ◽

Chest X Ray ◽

Severe Degree

Introduction: Pulmonary tuberculosis (TB) cases increase along with the increase in diabetes mellitus (DM) cases. The purpose of this study is to compare the description of Thorax X-ray severity between pulmonary TB patients without DM and pulmonary TB patients with DM.

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