scholarly journals Phylogenomic Pipeline Validation for Foodborne Pathogen Disease Surveillance

2019 ◽  
Vol 57 (5) ◽  
Author(s):  
Ruth E. Timme ◽  
Errol Strain ◽  
Joseph D. Baugher ◽  
Steven Davis ◽  
Narjol Gonzalez-Escalona ◽  
...  

ABSTRACT Foodborne pathogen surveillance in the United States is transitioning from strain identification using restriction digest technology (pulsed-field gel electrophoresis [PFGE]) to shotgun sequencing of the entire genome (whole-genome sequencing [WGS]). WGS requires a new suite of analysis tools, some of which have long histories in academia but are new to the field of public health and regulatory decision making. Although the general workflow is fairly standard for collecting and analyzing WGS data for disease surveillance, there are a number of differences in how the data are collected and analyzed across public health agencies, both nationally and internationally. This impedes collaborative public health efforts, so national and international efforts are underway to enable direct comparison of these different analysis methods. Ultimately, the harmonization efforts will allow the (mutually trusted and understood) production and analysis of WGS data by labs and agencies worldwide, thus improving outbreak response capabilities globally. This review provides a historical perspective on the use of WGS for pathogen tracking and summarizes the efforts underway to ensure the major steps in phylogenomic pipelines used for pathogen disease surveillance can be readily validated. The tools for doing this will ensure that the results produced are sound, reproducible, and comparable across different analytic approaches.

2021 ◽  
pp. 000276422199283
Author(s):  
Serena Tagliacozzo ◽  
Frederike Albrecht ◽  
N. Emel Ganapati

Communicating during a crisis can be challenging for public agencies as their communication ecology becomes increasingly complex while the need for fast and reliable public communication remains high. Using the lens of communication ecology, this study examines the online communication of national public health agencies during the COVID-19 pandemic in Italy, Sweden, and the United States. Based on content analysis of Twitter data ( n = 856) and agency press releases ( n = 95), this article investigates two main questions: (1) How, and to what extent, did national public health agencies coordinate their online communication with other agencies and organizations? (2) How was online communication from the agencies diversified in terms of targeting specific organizations and social groups? Our findings indicate that public health agencies relied heavily on internal scientific expertise and predominately coordinated their communication efforts with national government agencies. Furthermore, our analysis reveals that agencies in each country differed in how they diversify information; however, all agencies provided tailored information to at least some organizations and social groups. Across the three countries, information tailored for several vulnerable groups (e.g., pregnant women, people with disabilities, immigrants, and homeless populations) was largely absent, which may contribute to negative consequences for these groups.


1991 ◽  
Vol 2 (2) ◽  
pp. 58-60
Author(s):  
Dennis J White

Investigation of the epidemiology of Lyme disease depends upon information generated from several sources. Human disease surveillance can be conducted by both passive and active means involving physicians, public health agencies and laboratories. Passive and active tick surveillance programs can document the extent of tick-borne activity, identify the geographic range of potential vector species, and determine the relative risk of exposure to Lyme disease in specific areas. Standardized laboratory services can play an important role in providing data. Epidemiologists can gain a better understanding of Lyme disease through the collection of data from such programs. The interpretation of data and provision of information to the medical and general communities are important functions of public health agencies.


Author(s):  
William Rice ◽  
Timothy Mateer ◽  
Peter Newman ◽  
Ben Lawhon ◽  
Nathan Reigner ◽  
...  

For nearly a century in the United States, visitor capacities have served as a means of preserving resources and the visitor experience on public lands. The COVID-19 pandemic resulted in increased interest in implementing visitor capacities that could potentially limit use on public lands, suggesting a need to understand public support for their use in a timely manner. Risk and trust have been used in previous research concerning support for natural resource and outdoor recreation decision-making. Research in this realm includes investigation at the intersection of outdoor recreation and public health, specific to chronic wasting disease. Following this previous research, this study utilizes the constructs of risk and trust to examine support for visitor capacities that could potentially limit use during the COVID-19 pandemic. Specifically, this theory-driven research relies on the cultural theory of risk and social trust theory. Using structural equation modeling and a sample of avid outdoor enthusiasts, we examine how well 1) perceived individual risk, 2) perceived community risk, 3) trust in public health agencies, and 4) trust in public land agencies predict support for visitor capacities that could potentially limit use. An email-distributed online survey was available for 48 hours beginning on April 30, 2020—during the first wave of the COVID-19 pandemic in the United States. Measurement of perceived risk and trust followed previous research relating to outdoor recreation and public health. Results indicate that outdoor enthusiasts are concerned about their individual and community health and reported higher levels of trust in data coming directly from public health agencies as opposed to state or federal land management agencies. Additionally, perceived individual risk and perceived community risk were significant predictors of support for visitor capacities. These findings can be used to improve the effectiveness of messaging intended to connect perceived risk to the management of parks and protected areas, thus providing credibility to management actions implemented during the pandemic. Additional implications from this research include the need for additional research examining support for management actions that could potentially limit use on public lands, the multidimensionality of trust in outdoor recreation, and individual risk in frontcountry outdoor recreation settings.


2019 ◽  
pp. 83-101
Author(s):  
Jonathan H. Marks

This chapter outlines several partnership case studies involving the food and beverage sector, especially soda companies. These case studies are drawn from the United States, Britain, and India. The analysis highlights certain problematic features—for example, use of corporate logos, trademarks, and color schemes that are likely to promote consumption of products that are exacerbating obesity and diet-related noncommunicable diseases (NCDs). But, more fundamentally, the analysis ties the case studies to the broader systemic effects discussed in the preceding chapters. These include framing effects, agenda distortion, and impacts on the integrity of and trust in public health agencies.


2020 ◽  
Vol 32 (4) ◽  
pp. 337-355 ◽  
Author(s):  
Katherine S. Elkington ◽  
Anne Spaulding ◽  
Sheena Gardner ◽  
Danica Knight ◽  
Steven Belenko ◽  
...  

Justice-involved youth are at high risk for HIV and STIs, and justice agencies are uniquely poised to offer HIV/STI testing. However, testing in these settings is not routine and represents a missed opportunity. This study describes a system-level implementation intervention designed to increase access to HIV/STI testing through juvenile justice (JJ) and public health agency collaboration across six counties in six states in the United States. Local change teams, active facilitation, and training were utilized to facilitate agency partnerships and development of HIV/STI practice change protocols. Five counties established health and JJ partnerships and four counties successfully implemented their protocols. Sites with HIV/STI education and testing protocols behaviorally screened 98.5% of youth and tested 41.2% of those youth; 0% were HIV+ and 43.2% had an STI. The intervention provides a feasible, scalable solution, through promoting partnerships between JJ and health agencies, to link youth to testing and treatment services.


2020 ◽  
Author(s):  
Raid Amin ◽  
Terri Hall ◽  
Jacob Church ◽  
Daniela Schlierf ◽  
Martin Kulldorff

AbstractBackgroundCOVID-19 is a new coronavirus that has spread from person to person throughout the world. Geographical disease surveillance is a powerful tool to monitor the spread of epidemics and pandemic, providing important information on the location of new hot-spots, assisting public health agencies to implement targeted approaches to minimize mortality.MethodsCounty level data from January 22-April 28 was downloaded from USAfacts.org to create heat maps with ArcMap™ for diagnosed COVID-19 cases and mortality. The data was analyzed using spatial and space-time scan statistics and the SaTScan™ software, to detect geographical cluster with high incidence and mortality, adjusting for multiple testing. Analyses were adjusted for age. While the spatial clusters represent counties with unusually high counts of COVID-19 when averaged over the time period January 22-April 20, the space-time clusters allow us to identify groups of counties in which there exists a significant change over time.ResultsThere were several statistically significant COVID-19 clusters for both incidence and mortality. Top clusters with high rates included the areas in and around New York City, New Orleans and Chicago, but there were also several small rural clusters. Top clusters for a recent surge in incidence and mortality included large parts of the Midwest, the Mid-Atlantic Region, and several smaller areas in and around New York and New England.ConclusionsSpatial and space-time surveillance of COVID-19 can be useful for public health departments in their efforts to minimize mortality from the disease. It can also be applied to smaller regions with more granular data.


2017 ◽  
Vol 13 (5) ◽  
pp. 273 ◽  
Author(s):  
Kieran Moore, MD, CCFP (EM), FCFP, MPH, DTM&H, FRCPC ◽  
Maximilien Boulet, BSc ◽  
Julia Lew, BSc ◽  
Nicholas Papadomanolakis-Pakis, BSocSc, MPA

Objective: Over the past decade, Canada and the United States have been facing an epidemic of harms from prescription opioids. More recently, opioid-naïve individuals have been exposed to illicit opioids through adulterated combination products. This has resulted in sudden surges of opioid-related mortality. A proactive public health solution is needed to prevent further death. We propose examining these surges in opioid overdoses as outbreaks and investigating them in a similar way to an outbreak of an infectious disease. An epidemiologic investigation model for opioid overdose outbreaks, that could be modified by other public health agencies,is discussed.


2009 ◽  
Vol 14 (18) ◽  
Author(s):  
ECDC Technical Emergency Team

The recent detection of a novel influenza A(H1N1) virus has led to the first WHO declaration of a Public Health Event of International Concern under the International Health Regulations (IHR 2005). Here we review the early epidemiological findings of confirmed cases in Mexico, the United States, Canada and EU/EFTA countries. Strengthened surveillance and continued, transparent communication across public health agencies globally will be necessary in coming months.


2021 ◽  
Vol 111 (S3) ◽  
pp. S201-S203
Author(s):  
Nolan Kline ◽  
Marco Antonio Quiroga

Structural racism is a root cause of poor health in the United States and underlies COVID-19–related disparities for Black and Latinx populations. We describe how one community-based organization responded to structural racism and COVID-19 in Florida. Informed by the literature on how public health practice changed from emphasizing prevention (Public Health 1.0) to collaboration between governmental and public health agencies (Public Health 2.0) and examining social determinants of health (Public Health 3.0), we call for a politically engaged Public Health 4.0. (Am J Public Health. 2021;111(S3):S201–S203. https://doi.org/10.2105/AJPH.2021.306408 )


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