scholarly journals Multicomponent Gold-Linked Glycoconjugate Vaccine Elicits Antigen-Specific Humoral and Mixed T H 1-T H 17 Immunity, Correlated with Increased Protection against Burkholderia pseudomallei

mBio ◽  
2021 ◽  
Author(s):  
Daniel Tapia ◽  
Javier I. Sanchez-Villamil ◽  
Heather L. Stevenson ◽  
Alfredo G. Torres
Keyword(s):  
Human Disease ◽  
Burkholderia Pseudomallei ◽  
Global Burden ◽  
Gram Negative ◽  
Content Type ◽  
Complex Human Disease ◽  
Negative Bacillus ◽  
Wide Range ◽  
Gram Negative Bacillus ◽  
Glycoconjugate Vaccine

Melioidosis is a complex human disease associated with a wide range of complications caused by the Gram-negative bacillus Burkholderia pseudomallei . The global burden of melioidosis is estimated to have 165,000 cases per year and 89,000 fatal outcomes.

scholarly journals Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Sitthi Sukauichai ◽  
Chantana Pattarowas
Keyword(s):  
Septic Shock ◽  
Mortality Rate ◽  
Burkholderia Pseudomallei ◽  
Neutropenic Patient ◽  
Pulmonary Nodules ◽  
Severe Infection ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
Chemotherapy Induced Neutropenia

Melioidosis is a bacterial infection, caused by Gram-negative bacillus, Burkholderia pseudomallei, widespread in Southeast Asia and the northern part of Australia, resulting in a high mortality rate in severe infection. However, it has rarely been reported in patients with chemotherapy-induced neutropenia. The authors described a case of melioidosis in a neutropenic patient presenting with septic shock after receiving chemotherapy. Blood and urine cultures were positive for Burkholderia pseudomallei, and CT scan showed multiple pulmonary nodules and hepatosplenic abscesses. The patient was successfully treated with antibiotics for the infection and with combined modalities for a malignancy.

scholarly journals Microbiological and Clinical Features of Four Cases of Catheter-Related Infection by Methylobacterium radiotolerans

2015 ◽  
Vol 53 (4) ◽  
pp. 1375-1379 ◽  
Author(s):  
Li Li ◽  
Jeffrey J. Tarrand ◽  
Xiang Y. Han
Keyword(s):  
Clinical Microbiology ◽  
Venous Catheter ◽  
Bacterial Strains ◽  
Central Venous ◽  
Gram Negative ◽  
Content Type ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
Yeast Extract Agar

Four cases of central venous catheter-relatedMethylobacterium radiotoleransinfection are presented here. The patients were all long-term catheter carriers with an underlying diagnosis of leukemia, and they mostly manifested fevers. The isolated bacterial strains all showed far better growth on buffered charcoal yeast extract agar during the initial isolation and/or subcultures than they did on sheep blood or chocolate agar. This microbiological feature may improve the culture recovery of this fastidious pink Gram-negative bacillus that has rarely been isolated in clinical microbiology laboratories.

scholarly journals CNS Melioidosis in a Traveler Returning from Cabo, Mexico

2019 ◽  
Vol 6 (2) ◽  
Author(s):  
Matthew A Donahue ◽  
Geoffrey Newcomb ◽  
Sara Spinella ◽  
Paritosh Prasad ◽  
Jane Liesveld ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Burkholderia Pseudomallei ◽  
Central Nervous System Disease ◽  
The United States ◽  
Northern Australia ◽  
Intensive Phase ◽  
Gram Negative ◽  
Negative Bacillus ◽  
System Disease ◽  
Gram Negative Bacillus

Abstract Melioidosis is caused by the gram-negative bacillus Burkholderia pseudomallei, endemic to northern Australia and Southeast Asia. We present a patient who traveled to Mexico, returned to the United States, and developed progressive manifestations of melioidosis, culminating as central nervous system disease. Standard therapy was contraindicated, and a prolonged intensive phase was employed.

scholarly journals Melioidosis by aminoglycoside susceptible Burkholderia pseudomallei: First case in Bangladesh

2021 ◽  
Vol 14 (2) ◽  
pp. 55-59
Author(s):  
Saika Farook ◽  
Md Shariful Alam Jilani ◽  
Alpona Akhter ◽  
J Ashraful Haq
Keyword(s):  
Male Patient ◽  
Burkholderia Pseudomallei ◽  
Etiological Agent ◽  
Gram Negative ◽  
Negative Bacillus ◽  
First Case ◽  
The World ◽  
Gram Negative Bacillus

Burkholderia pseudomallei is the etiological agent of melioidosis. It is a gram-negative bacillus present in environment and intrinsically resistant to many antibiotics including aminoglycosides. However, recently aminoglycoside susceptible B. pseudomallei has been isolated from melioidosis cases and reported from some countries of the world. But, such aminoglycoside susceptible B. pseudomallei has never been detected in Bangladesh either from melioidosis cases or from environment. All the B. pseudomallei isolated so far in Bangladesh were resistant to gentamicin and other aminoglycosides. Here, we describe a disseminated case of melioidosis caused by aminoglycoside susceptible B. pseudomallei in a 55 years old Bengali male patient. This is the first case of melioidosis due to aminoglycoside susceptible B. pseudomallei in Bangladesh. Ibrahim Med. Coll. J. 2020; 14(2): 55-59

scholarly journals Bipolar staining of gram-negative bacillus in cerebrospinal fluid

Blood ◽  
2014 ◽  
Vol 124 (18) ◽  
pp. 2892-2892
Author(s):  
Lori D. Racsa ◽  
Eileen M. Burd
Keyword(s):  
Cerebrospinal Fluid ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus

scholarly journals Meningitis Caused by Salmonella Newport in a Five-Year-Old Child

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Ana De Malet ◽  
Sheila Ingerto ◽  
Israel Gañán
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurological Disorders ◽  
Invasive Disease ◽  
Salmonella Typhi ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Salmonella Newport ◽  
Gram Negative Bacillus ◽  
The Central Nervous System

Salmonella Newport is a Gram-negative bacillus belonging to the Enterobacteria family and the nontyphi Salmonella (NTS), usually related to gastroenteritis. Main difference between NTS and Salmonella typhi is that the last one evolves to an invasive disease easier than NTS. These can progress to bacteremias in around 5% of cases and secondary focuses can appear occasionally, as in meningitis. An infection of the central nervous system is uncommon, considering its incidence in 0.6–8% of the cases; most of them are described in developing countries and mainly in childhood, especially neonates. Bacterial meningitis by NTS mostly affects immunosuppressed people in Europe. Prognosis is adverse, with a 50% mortality rate, mainly due to complications of infection: hydrocephalus, ventriculitis, abscesses, subdural empyema, or stroke. Choice antibiotic treatments are cefotaxime, ceftriaxone, or ceftazidime. The aim of this paper is to present a case of meningitis caused by Salmonella Newport diagnosed in a five-year-old girl living in a rural area of the province of Ourense (Spain), with favorable evolution and without neurological disorders.

Melioidosis and glanders

2010 ◽  
pp. 768-772
Author(s):  
S.J. Peacock
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Northern Australia ◽  
Gram Negative ◽  
Negative Bacillus ◽  
North East ◽  
Serious Infection ◽  
The World ◽  
Gram Negative Bacillus ◽  
Sixth Decade

Melioidosis is a serious infection caused by the soil-dwelling Gram-negative bacillus Burkholderia pseudomallei. It is most commonly reported in north-east Thailand and northern Australia, but is increasingly recognized around the world. Infection is predominantly acquired through bacterial inoculation, often related to occupation, and mostly affects adults between the fourth and sixth decade who have risk factors such as diabetes mellitus and renal impairment....

A Gram-negative Bacillus Infection Causing Gill Lesions in Cultured Rockfish Sebastes schlegeli

2005 ◽  
Vol 40 (3) ◽  
pp. 143-145 ◽  
Author(s):  
Tatsuya Kobayashi ◽  
Makoto Imai ◽  
Yoshifumi Kawaguchi
Keyword(s):  
Sebastes Schlegeli ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus
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