Effectiveness of Acupuncture in Postpartum Depression: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 36 (5) ◽  
pp. 295-301 ◽  
Author(s):  
Shanshan Li ◽  
Weiqiang Zhong ◽  
Wen Peng ◽  
Gaofeng Jiang
Keyword(s):  
Postpartum Depression ◽  
Rating Scale ◽  
Meta Analysis ◽  
Depression Scale ◽  
Cochrane Collaboration ◽  
Clinical Effectiveness ◽  
Effective Rate ◽  
Cochrane Library ◽  
Secondary Outcome ◽  
Control Group

Objective To assess the clinical effectiveness of acupuncture in the treatment of postpartum depression (PPD). Methods The following electronic databases were systematically searched: PubMed, Cochrane Library, SCI, Elsevier SDOL, China National Knowledge, Wan Fang database and Chinese Science and Technology Periodical Database. Only randomised controlled trials (RCTs) of acupuncture for PPD were considered. Primary outcomes were the Hamilton Rating Scale for Depression (HAMD) or the Edinburgh Postnatal Depression Scale (EPDS) scores and effective rate. Our secondary outcome was the level of oestradiol. The quality of all included trials was evaluated according to the Cochrane Collaboration. This protocol was registered in PROSPERO (CRD42016048528). Results Nine trials involving 653 women were selected. The result of this meta-analysis demonstrated that the acupuncture group had a significantly greater overall effective rate compared with the control group (seven trials, n=576, I2=24%; relative risk (RR) 1.15, 95% CI 1.06 to 1.24; P<0.001). Moreover, acupuncture significantly increased oestradiol levels compared with the control group (mean difference (MD) 36.92, 95% CI 23.14 to 50.71, P<0.001). Regarding the HAMD and EPDS scores, no difference was found between the two groups (five trials, n=276, I2=82%; MD−1.38, 95% CI −3.40 to 0.64; P=0.18; two trials, n=60, I2=16%; MD 1.08, 95% CI −1.09 to 3.26; P=0.33). Conclusions Acupuncture appears to be effective for postpartum depression with respect to certain outcomes. However, the evidence thus far is inconclusive. Further high-quality RCTs following standardised guidelines with a low risk of bias are needed to confirm the effectiveness of acupuncture for postpartum depression.

The effectiveness of mHealth interventions on postpartum depression: A systematic review and meta-analysis

2020 ◽  
pp. 1357633X2091781
Author(s):  
Chuqing Zhou ◽  
Hua Hu ◽  
Chunyi Wang ◽  
Ziyu Zhu ◽  
Gengchen Feng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Postpartum Depression ◽  
Large Scale ◽  
Meta Analysis ◽  
Clinical Care ◽  
Intervention Group ◽  
Depression Scale ◽  
Clinical Effectiveness ◽  
Well Being ◽  
Cochrane Library

Introduction Postpartum depression (PPD) is a common psychiatric condition during the postnatal period that negatively impacts the well-being of both the mother and her infant. This study describes a systematic review and preliminary meta-analysis to assess the efficacy of mobile health (mHealth) interventions, which is defined as the use of portable electronic devices to support public health and medical practice, in addressing depressive symptoms among postpartum women. Methods Databases including PubMed, PsycINFO, the Cochrane Library, Embase and ClinicalTrials.gov were searched for randomized controlled trials (RCTs) assessing the effectiveness of mHealth interventions on PPD from database inception to December 2019. Results The initial search identified 754 studies, of which, 11 studies fulfilled the inclusion criteria. These studies evaluated four types of distinct mHealth interventions and involved 2424 participants across six countries. Pooled results demonstrated that compared to the controls, the Edinburgh Postnatal Depression Scale score decreased in the mHealth intervention group (mean difference: –1.09, 95% confidence interval: –1.39 to –0.79). Discussion Our study suggested that mHealth interventions may be a promising tool to complement routine clinical care in the prevention and treatment of PPD, but the clinical effectiveness of mHealth interventions needs to be better established. While most studies focused on telephone-based interventions, recent researches have also suggested the superiority and effectiveness of short messaging service (SMS) and smartphone applications, but the exact efficacy needs further evaluation. Therefore, more high-quality RCTs on app-based and SMS-based interventions are needed before the large-scale roll-out of these interventions in clinical practice.

scholarly journals Moxibustion for Chronic Pelvic Inflammatory Disease：A systematic review and meta-analysis

2021 ◽  
Author(s):  
Fanghui Hua ◽  
Jun Xiong ◽  
Shouqiang Huang ◽  
Jie Xiang
Keyword(s):  
Meta Analysis ◽  
Scientific Journal ◽  
Cochrane Collaboration ◽  
Effective Rate ◽  
Cochrane Library ◽  
Control Group ◽  
Inflammatory Factor ◽  
China National Knowledge Infrastructure ◽  
Evidence Level ◽  
Control Therapy

Background: This study was performed to strictly evaluate the quality of RCTs and thus test the effect of moxibustion on CPID. Methods: Seven databases (PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure, WangFang Database, Chinese Scientific Journal Database, Chinese Biomedical Literatures Database were reviewed for RCTs on CPID treated by moxibustion up to September 2020. Methodological quality and evidence level was assessed on the basis of the RoB tool from Cochrane collaboration and the GRADE instrument, respectively. RevMan5.4.1 and Stata 12.0 software were used for further meta-analysis.Results: A total of 17 RCTs were included (1315 participants, 515 treated by moxibustion and 515 treated by control therapy). The meta-analysis showed that, in comparison to control group, moxibustion had a higher total effective rate (RR = 1.21; 95% CI [1.31, 1.29]; P = 0.007; I2 = 53%); and lower total symptom score (MD = -3.72; 95% CI [-4.38, -3.06]; P =0.02; I2 = 66%). As for the total sign score, the participants treated by moxibustion had lower scores than those treated by control therapy(SMD = -0.72; 95% CI [ -1.07, -0.37]; P = 0.36; I2 = 0%). For the VAS score, pelvic fluid and inflammatory factor level, only one trial showed that there was a significant effect, respectively. Conclusions: This study shows that moxibustion is more effective and safe for CPID. The findings we obtained must be interpreted with caution due to universal low quality and low evidence level of the eligible trials.

scholarly journals Effectiveness and Safety of Moxibustion on Constipation: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Fang Yao ◽  
Yang Zhang ◽  
Xiaohong Kuang ◽  
Qi Zhou ◽  
Lihua Huang ◽  
...  
Keyword(s):  
Moxibustion Therapy ◽  
Meta Analysis ◽  
Clinical Effectiveness ◽  
Effective Rate ◽  
Cochrane Library ◽  
Good Effect ◽  
Control Group ◽  
Safety Level ◽  
Experimental Group

Aim. This study aimed to evaluate the effects and safety of moxibustion in the management of constipation. Background. Constipation is extremely common in clinical practice and causes physical and mental pain to patients. This study aimed to evaluate the effects and safety of moxibustion in the management of constipation. Methods. Studies on moxibustion for constipation published up to November 2019 were searched in PubMed; EBSCO; EMBASE; Cochrane Library; and three Chinese databases, namely, China National Knowledge Internet, Wanfang, and China Biomedical Network. The methodological quality of the included studies was assessed on the basis of the CLEAR NPT system evaluation methods of Boutron. Further meta-analysis was performed using the RevMan 5.3 and Stata 15.0 software. Results. Ten randomized controlled trials involving 760 patients were included in this study. The meta-analysis revealed that, in comparison to western medicine treatment or other Chinese medicine methods (control group), moxibustion (experimental group) had a higher total effective rate (RR = 1.30, 95% CI [1.21, 1.40], P<0.00001), and the clinical effectiveness of the experimental group was higher than that of the control group in any subgroup analysis. The first defecation time of the experimental group was shorter than that of the control group (SMD = −1.36, 95% CI [−2.03, −0.68], P<0.0001). The clinical symptom score of the patients in the experimental group was lower than that in the control group (SMD = −0.65, 95% CI [−1.00, −0.30], P=0.0003). The patients in the experimental group had higher scores on Bristol stool form scale than those in the control group (MD = 0.99, 95% CI [0.48, 1.50], P=0.0001). However, there was no obvious difference in safety between the two groups (RR = 0.38, 95% CI [0.01, 11.8], P=0.58). Conclusions. Moxibustion may have better effect than other treatments on constipation. However, it is not yet possible to assess the safety level of moxibustion therapy, and the quality of the included literature is low, so rigorous studies are warranted. Implications for Nursing and Health Policy. The focus of this study was to evaluate the effectiveness and safety of moxibustion therapy in constipation. This evaluation showed that moxibustion therapy has a good effect on constipation and provides an effective treatment for constipation patients. Whether moxibustion therapy can be used for different syndrome types deserves further discussion.

scholarly journals The Effectiveness of Telehealth Interventions on Women with Postpartum Depression: A Systematic Review and Meta-Analysis (Preprint)

2021 ◽  
Author(s):  
Liuhong Zhao ◽  
Jingfen Chen ◽  
Yan Liao ◽  
Liuying Lan ◽  
Ni Deng ◽  
...  
Keyword(s):  
Social Support ◽  
Systematic Review ◽  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Large Scale ◽  
Meta Analysis ◽  
Treatment Strategies ◽  
Depression Scale ◽  
Cochrane Library ◽  
Control Group

BACKGROUND Background: Postpartum depression is a highly prevalent mental health problem with potential for serious adverse consequences. Telehealth interventions can increase the accessibility to treatments for postpartum depression and their effectiveness has been assessed by clinical trials. However, no comprehensive synthesis of findings by systematic review has been conducted. OBJECTIVE Objective: To evaluate the effectiveness of telehealth interventions on women with postpartum depression in terms of reducing depressive symptoms, anxiety and loneliness, and improving social support. METHODS Methods: PubMed, The Cochrane Library, CINAHL, PsycINFO, CNKI, and Wan Fang database were electronically searched to identify studies with randomized controlled trials (RCTs) on the effectiveness of telehealth interventions on women with postpartum depression from inception to February 28, 2021. Data extraction and quality assessment were performed by two researchers independently. The quality of included studies was assessed using the Cochrane risk-of-bias tool, and meta-analysis was performed using RevMan 5.4 software. RESULTS Results: A total of 1,958 women with postpartum depression from nine RCTs were included. The meta-analysis showed that the scores of Edinburgh Postnatal Depression Scale (EPDS) [MD=-2.99, 95%CI (-4.52, -1.46), P<.001] and anxiety [SMD=-0.39, 95%CI (-0.67, -0.12), P=.005] were significantly lower in the telehealth group compared with the control group. No significant differences were observed for social support and loneliness. Significant subgroup differences were found for depressive symptoms according to the severity of postpartum depression, telehealth technology used, specific therapy, and follow up time periods (P<.001). CONCLUSIONS Conclusions: Telehealth interventions are effective in reducing depression and anxiety in women with postpartum depression. However, large scale RCTs targeting specific therapies in women are needed to help tailor treatment strategies to individuals. CLINICALTRIAL PROSPERO CRD42021258541; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258541

scholarly journals The Treatment of Acne with the Addition and Subtraction of Loquat Qingfei Yin: A Meta-Analysis

2021 ◽  
Vol 5 (4) ◽  
pp. 167-176
Author(s):  
Wenjun Xue ◽  
Pengguang Xu
Keyword(s):  
Large Scale ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Cochrane Collaboration ◽  
Effective Rate ◽  
Cochrane Library ◽  
Control Group ◽  
Comprehensive Collection

Objective: To systematically evaluate the efficacy and safety of Loquat Qingfei Yin (LQFY) in the treatment of acne. Methods: Using computer retrieval, comprehensive collection of the full text database of Chinese journals till December 2020 (CNKI), Wanfang Data Knowledge Service Platform (Wanfang), Viper Database (VIP), PubMed, Cochrane Library, Medline were included in the LQFY addition or subtraction treatment of acne randomized controlled trial (RCT). Screening of the literatures included in the Note Express 3.2.0. Assessment of the risk of bias in trials using Cochrane collaboration tools, and used Rev Man 5.3 to evaluate the curative effect. Results: 25 RCT, all in Chinese, there were 2257 cases. Of the 1216 cases who were treated, control group was 1041 cases. A random effect model was used for Meta analysis. The results showed that the effective rate of the treatment group was significantly higher than that of the control group, Differences were statistically significant (P=0.94, I2=0%), RR=2.87, CI [2.25,95 per cent 3.67], P<0.00001. Conclusion: There are limited evidence that LQFY is safe and effective in treating acne. However, this conclusion needs to be confirmed by a more large-scale, multi-center, high-quality RCTs.

scholarly journals Clinical Effects and Safety of Electroacupuncture for the Treatment of Poststroke Dysphagia: A Comprehensive Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Jinke Huang ◽  
Yao Shi ◽  
Xiaohui Qin ◽  
Min Shen ◽  
Manli Wu ◽  
...  
Keyword(s):  
Rating Scale ◽  
Meta Analysis ◽  
Effective Rate ◽  
Control Treatment ◽  
Sufficient Evidence ◽  
Cochrane Library ◽  
Clinical Effects ◽  
Knowledge Infrastructure ◽  
Swallowing Rehabilitation ◽  
Chinese National Knowledge Infrastructure

Objectives. Electroacupuncture (EA), an extension of acupuncture, which is based on traditional acupuncture combined with modern electrotherapy, is commonly used for poststroke dysphagia (PSD) in clinical treatment and research. However, there is still a lack of sufficient evidence to recommend the routine use of EA for PSD. The aim of this study was to assess the efficacy and safety of EA in the treatment of PSD. Methods. Randomized controlled trials (RCTs) evaluating the effects of EA on PSD were identified through a comprehensive literature search of the PubMed, Embase, Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure, Chinese Biomedical Database, and VIP databases from their inception to July 2020. The quality assessment of the included trials was performed based on the guidance of the Cochrane Reviewers’ Handbook, and meta-analysis (MA) was performed by using the RevMan 5.3 software. Results. Sixteen trials were identified, and these included 1,216 patients with PSD. The results demonstrated that EA in combination with swallowing rehabilitation training (SRT) was significantly superior to SRT alone with regard to effective rate (OR 5.40, 95% CI [3.78, 7.72], P < 0.00001 , water swallow test (WST) (MD −0.78, 95% CI [−1.07, −0.50], P < 0.00001 ), the video fluoroscopic swallowing study (VFSS) (MD 1.47, 95% CI [1.11, 1.84], P < 0.00001 ), the Ichiro Fujishima Rating Scale (IFRS) (MD 1.94, 95% CI [1.67, 2.22], P < 0.00001 ), and the incidence of aspiration pneumonia (IAP) (OR 0.20, 95% CI [0.06, 0.61], P = 0.005 ). Conclusions. The results showed that EA was better than the control treatment in terms of the effective rate, WST, VFSS, IFRS, and IAP of dysphagia after stroke. Strict evaluation standards and high-quality RCT designs are necessary for further exploration.

scholarly journals Xiao’er Xiaoji Zhike Oral Liquid Combined with Azithromycin for Mycoplasma pneumoniae Pneumonia in Children: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Gui-Min Zhang ◽  
Zhi-Yan Huang ◽  
Rong Sun ◽  
Shi-Li Ye ◽  
Qun Feng
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Meta Analysis ◽  
Scientific Journal ◽  
Effective Rate ◽  
Biomedical Literature ◽  
Cochrane Library ◽  
Control Group ◽  
X Ray ◽  
Disappearance Time ◽  
Oral Liquid

Background. This study was aimed at systematically evaluating the clinical effect and safety of Xiao’er Xiaoji Zhike oral liquid in the treatment of Mycoplasma pneumoniae pneumonia (MPP) in children and providing evidence-based references for clinical application. Methods. The databases like Chinese Biomedical Literature Database, China Network Knowledge Infrastructure, Wan Fang Database, Chinese Scientific Journal Database, PubMed, EmBase, and the Cochrane Library were systematically investigated via searching clinical trials about Xiao’er Xiaoji Zhike oral liquid in treating MPP from the establishment of these databases to Jun 8, 2020, the valid data from which were entered meta-analysis. The quality of evidence was assessed by GRADE criteria. Results. Totally, 15 trials and 1500 patients were involved in this review. It showed that clinical efficacy of trial group was more superior than control group at the outcome measures of cough disappearance time, lung rale disappearance time, fever subsidence time, total effective rate, lung X-ray infiltrates disappearing time, reduction of hospital stay, immunological indexes, and some other measures. And the differences between groups were statistically significant. There was no statistical difference in the adverse effects between two groups. Lung X-ray infiltrates disappearing time and cough disappearance time were separately high- and moderate-quality evidences while lung rale disappearance time and fever subsidence time were all low in accordance with GRADE criteria. Conclusions. In accordance with trials with low methodological quality, Xiao’er Xiaoji Zhike oral liquid combined with azithromycin seems to be safe and superior to azithromycin alone for the treatment of MPP in children. However, further trials with rigorous methodology need to be implemented for these potential benefits.

scholarly journals The Impact of a Stabilization Exercise on Neck Pain: A Systematic Review and Meta-analysis

2020 ◽  
Vol 81 (04) ◽  
pp. 342-347
Author(s):  
Binbin Wu ◽  
Hongyan Yuan ◽  
Deyu Geng ◽  
Liang Zhang ◽  
Cheng Zhang
Keyword(s):  
Systematic Review ◽  
Neck Pain ◽  
Meta Analysis ◽  
Neck Disability Index ◽  
Depression Scale ◽  
Cochrane Library ◽  
Control Group ◽  
Stabilization Exercise ◽  
Pain Scores ◽  
The Impact

Abstract Introduction The efficacy of a stabilization exercise for the relief of neck pain remains controversial. We conducted a systematic review and meta-analysis to explore the effectiveness of a stabilization exercise on neck pain. Methods We searched Embase, Web of Science, EBSCO Information Services, and the Cochrane Library databases through May 2019 for randomized controlled trials (RCTs) assessing the impact of a stabilization exercise on neck pain. This meta-analysis was performed using the random effects model. Results Six RCTs are included in the meta-analysis. Compared with the control group of patients with neck pain, a stabilization exercise can significantly reduce pain scores at 4 to 6 weeks (mean difference [MD]: −2.41; 95% confidence interval [CI], −4.46 to −0.35; p = 0.02), Neck Disability Index [NDI] at 10 to 12 weeks (MD:− 6.75; 95% CI, −11.71 to −1.79; p = 0.008), and depression scale at 4 to 6 weeks (MD: −4.65; 95% CI, −7.00 to −2.31; p = 0.02), but it has no obvious impact on pain scores at 10 to 12 weeks (MD: −1.07; 95% CI, −3.42 to 1.28; p = 0.37) or at 6 months (MD: −1.02; 95% CI, −3.43 to 1.39; p = 0.41). Conclusions A stabilization exercise can provide some benefits to control neck pain.

A Meta-Analysis of Au/Polypropionic Acid Nanoparticles Loaded with Olacetam for the Treatment of Vascular Cognitive Impairment

2020 ◽  
Vol 20 (12) ◽  
pp. 7433-7438
Author(s):  
Zhen Yi ◽  
Weiheng Liang ◽  
Wenwen Ruan ◽  
Wei Hua ◽  
Xinjing Lin
Keyword(s):  
Cognitive Dysfunction ◽  
Meta Analysis ◽  
Vascular Cognitive Impairment ◽  
Effective Rate ◽  
Positive Control ◽  
Cochrane Library ◽  
Control Group ◽  
Placebo Control ◽  
Checklist Score ◽  
Group A

To systematically evaluate the efficacy and safety of oxetam in the treatment of vascular cognitive dysfunction and the feasibility of an Au/polypropionic acid Nanometer drug delivery system to provide evidence for clinical application. PubMed, Shanghai embase, Cochrane Library, CNKI, VIP information, and Wanfang database were searched from the establishment of the database to April 2018. Patients were divided into two groups according to whether they received olacetam: the experimental group and the control group. In addition, the control group was divided into the placebo control group and the positive control group according to whether the control group received a placebo or other medication treatment controls. In the control group, a meta-analysis, a publication bias assessment, and sensitivity analysis were performed with Revman 5.3 and Stata 14.0. The results of the meta-analysis showed that compared with placebo and other medications, oxiracetam significantly improved the mental status of patients, Concise Mental State Checklist score [mean difference (MD)= 5.29, P < 0.01] and Montreal Cognitive Assessment score (MD = 4.32, P < 0.01). The Barthel Index demonstrated that oxiracetam significantly improved the quality of the daily life of patients (MD = 18, P < 0.01), but there was no difference between olacetam and placebo or other medications in the rating of activities of daily living (ADLs). The total effective rate of olacetam was significantly higher than that of other treatments (P < 0.01). Compared with placebo and other medications, the safety of oxiracetam was not significantly different (P > 0.05). Based on the current clinical evidence, olacetam is more effective and safer than alternatives in the treatment of vascular cognitive dysfunction.

scholarly journals Changes in apical base sagittal relationship in Class II malocclusion treatment with and without premolar extractions: A systematic review and meta-analysis

2016 ◽  
Vol 87 (2) ◽  
pp. 338-355 ◽  
Author(s):  
Guilherme Janson ◽  
Aron Aliaga-Del Castillo ◽  
Ana Niederberger
Keyword(s):  
Meta Analysis ◽  
Cochrane Collaboration ◽  
Class Ii ◽  
Risk Of Bias ◽  
Sensitivity Analyses ◽  
Cochrane Library ◽  
Control Group ◽  
Qualitative Synthesis ◽  
Class Ii Treatment ◽  
Apical Base

ABSTRACT Objective: To evaluate the changes in apical base sagittal relationship in Class II treatment with and without premolar extractions. Materials and Methods: Controlled studies evaluating ANB angle changes after Class II Division 1 malocclusion treatment with or without premolar extractions were considered. Electronic databases (PubMed, Embase, Web of Science, Scopus, The Cochrane Library, Lilacs, and Google Scholar) without limitations regarding publication year or language were searched. Risk of bias was assessed with Risk Of Bias in Non-randomized Studies—of Interventions tool of the Cochrane Collaboration. Mean difference (MD) and 95% confidence interval (CI) were calculated from the random-effects meta-analysis. Subgroup and sensitivity analyses were also performed. Results: Twenty-five studies satisfied the inclusion criteria and were included in the qualitative synthesis. Eleven nonextraction and only one extraction Class II treatment studies presented untreated Class II control group. Therefore, meta-analysis was performed only for the nonextraction protocol. In treated Class II nonextraction patients, the average of the various effects was a reduction in the ANB angle of 1.56° (95% CI: 1.03, 2.09, P &lt; .001) compared with untreated Class II subjects. Class II malocclusions treated with two maxillary-premolar extractions and four-premolar extractions produced estimated mean reductions in ANB of −1.88° and −2.55°, respectively. However, there is a lack of low-risk-of-bias studies. Conclusions: According to the existing low quality evidence, the apical base sagittal relationship in nonextraction, two-maxillary and four-premolar extractions Class II treatments decreases −1.56°, 1.88° and 2.55°, respectively. Further studies are necessary to obtain more robust information.

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