scholarly journals Association between suicide behaviours in children and adolescents and the COVID-19 lockdown in Paris, France: a retrospective observational study

2020 ◽  
pp. archdischild-2020-320628
Author(s):  
Maymouna Mourouvaye ◽  
Hugo Bottemanne ◽  
Guillaume Bonny ◽  
Lola Fourcade ◽  
Francois Angoulvant ◽  
...  
Keyword(s):  
Observational Study ◽  
Children And Adolescents ◽  
Help Seeking ◽  
Retrospective Observational Study ◽  
Temporal Association ◽  
Admission Rates ◽  
Suicide Behaviour ◽  
Adjusted Incidence Rate ◽  
Sick Children ◽  
Adjusted Incidence

This retrospective observational study conducted in Necker Hospital for Sick Children, France (January 2018–June 2020) evaluated a potential temporal association between admissions for suicide behaviours in children and adolescents and the national COVID-19 lockdown (March–May 2020). During the study period, 234 patients were admitted for suicide behaviours (28% male; mean age 13.4 years). Using Poisson regression, we found a significant decrease in the incidence of admissions for suicide behaviour during the lockdown (adjusted incidence rate ratio: 0.46; 95% CI 0.24 to 0.86). This association might result from reduced help-seeking and decreased hospital admission rates during the lockdown, as well as cognitive and environmental factors. Further multicentre studies should be conducted to confirm these findings and investigate whether a compensatory rise in admissions for suicide behaviour occurred in the postlockdown period.

Traumatic skull fractures in children and adolescents: A retrospective observational study

Injury ◽  
2018 ◽  
Vol 49 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Hongwei Wang ◽  
Yue Zhou ◽  
Jun Liu ◽  
Lan Ou ◽  
Jianda Han ◽  
...  
Keyword(s):  
Observational Study ◽  
Children And Adolescents ◽  
Retrospective Observational Study ◽  
Skull Fractures ◽  
Fractures In Children

scholarly journals Trends in the incidence and mortality of legionellosis in Japan: a nationwide observational study, 1999–2017

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shinnosuke Fukushima ◽  
Hideharu Hagiya ◽  
Yuki Otsuka ◽  
Toshihiro Koyama ◽  
Fumio Otsuka
Keyword(s):  
Observational Study ◽  
Vital Statistics ◽  
Middle Part ◽  
Incidence Trends ◽  
Geographical Variations ◽  
Incidence And Mortality ◽  
Adjusted Incidence Rate ◽  
Nationwide Observational Study ◽  
Warming World ◽  
Adjusted Incidence

AbstractThis study examined temporal trend, seasonality, and geographical variations of legionellosis incidence and mortality in Japan. This nationwide observational study used the Japanese Vital Statistics and Infectious Diseases Weekly Report (1999–2017) data to calculate legionellosis crude and age-adjusted incidence and mortality rates per 100,000 population by age and sex. Incidence was compared among the 4 seasons and regional incidence among 47 prefectures. Of 13,613 (11,194 men) people with legionellosis in Japan, 725 (569 men) were fatal. Increasing incidence trend occurred from 0.0004 (1999) to 1.37 (2017) per 100,000 population. People aged ≥ 70 years accounted for 43.1% overall; men’s age-adjusted incidence rate was consistently approximately five times higher than for women. Significantly higher incidence occurred in summer than in winter (p = 0.013). Geographically, highest incidence (≥ 2.0 per 100,000 population) occurred in Hokuriku District, with increasing trends in Hokkaido and middle-part of Japan. Estimated fatality rates decreased consistently at 5.9% (95% confidence interval: − 8.1, − 3.5) annually, from 1999 to 2017, with no trend change point. Increasing legionellosis incidence occurred in Japan during 1999–2017, with declining estimated fatality rates. In this aging society and warming world, disease clinical burden may further deteriorate in future due to increasing incidence trends.

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

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