scholarly journals Benign myoepithelioma of the soft palate: an unusual clinical entity

2021 ◽  
Vol 14 (6) ◽  
pp. e240384
Author(s):  
Marianna Guadalupe Mireles ◽  
Angelica Julián ◽  
Fabiola Salgado-Chavarría ◽  
Guillermo Manuel González
Keyword(s):  
Soft Palate ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Histopathological Diagnosis ◽  
Exocrine Glands ◽  
Present Case Report ◽  
Common Location ◽  
Benign Tumours ◽  
Growing Mass

Myoepitheliomas are rare benign tumours that affect the exocrine glands and are sporadically located in the salivary glands. The most common location of myoepithelioma in the oral cavity is the parotid gland and it is seldom encountered in the palate. The diagnosis of this entity is challenging since its clinical presentation may resemble those of more common neoplasms, rendering a complex histopathological diagnosis. The aim of the present case report is to describe an unusual case of myoepithelioma of the soft palate in a male patient, which developed as an asymptomatic, slowly growing mass. The tumour was assessed with histopathological examination and the diagnosis was verified via immunohistochemistry. Finally, the treatment included surgical resection of the tumour and no signs of recurrence were noted 2.5 years after the surgical procedure. Early diagnosis and treatment plays an important role in the prognosis of this pathological entity.

scholarly journals Seborrheic keratosis of the nasal tip-an unusual case report

2016 ◽  
Vol 21 (2) ◽  
pp. 119-121
Author(s):  
Abdullah Al Mamun ◽  
Dewan Mahmud Hasan
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Histopathologic Examination ◽  
Seborrheic Keratosis ◽  
Hyperkeratotic Lesion ◽  
Unusual Case Report ◽  
Skin Mucosa

Seborrheic keratosis is a benign tumour of skin, a common hyperkeratotic lesion of the epidermis,that usually occurs in the trunk and less frequently in the extremities, face and the scalp. A 65-year old farmer presented with a long standing, slowly growing, firm, redbrown, polypoidal mass about 2×2.5 cm in size, located at the skin mucosa interfare of the tip of nose. The lesion was excised under general anesthesia and histopathologic examination showed seborrheic keratosis. Diagnosis is made on the basis of clinical & histopathological examination. Here, we discuss the clinical presentation, differential diagnosis, pathological diagnosis and management of such a case. There was no recurrence during a year follow-up.Bangladesh J Otorhinolaryngol; October 2015; 21(2): 119-121

A Rare Case of Rhinofacial Zygomycosis due to Conidiobolus Infection

2014 ◽  
Vol 6 (2) ◽  
pp. 32-33
Author(s):  
Arunabha Chakravarti ◽  
Meenakshi Mishra
Keyword(s):  
Unusual Case ◽  
Clinical Presentation ◽  
Excellent Result ◽  
Histopathological Diagnosis ◽  
Maxillofacial Region ◽  
Immunocompetent Adult ◽  
Subcutaneous Tissues ◽  
Endoscopic Debridement ◽  
Multiple Drugs ◽  
Treatable Condition

ABSTRACT Background Rhinofacial zygomycosis is the infection of subcutaneous tissues of maxillofacial region caused by zygomycetes class of fungi. It is commonly caused by the order mucorales and is acute and fulminant. Infections by the order entomophthorales are rare but indolent. Case report We report an unusual case of rhinofacial zygomycosis due to Conidiobolus coronatus of the order Entomophthorales in an immunocompetent adult male to highlight the clinical presentation, diagnosis and treatment. We treated the patient with multiple drugs, that is amphotericin-B, cotrimoxazole, and itraconazole along with endoscopic debridement of nasal polyps with excellent result. Conclusion Rhinofacial zygomycosis due to entomophthorales is rare but treatable condition. Appropriate histopathological diagnosis and a multipronged approach with timely medical as well as surgical management is the key to clinical cure.

scholarly journals Spectrum of Oral Cavity Lesions and its Clinico-Histopathological Correlation

2021 ◽  
Vol 1 (2) ◽  
pp. 42-47
Author(s):  
Deepshikha Gaire ◽  
Anil Dev Pant ◽  
Daisy Maharjan ◽  
Usha Manandhar
Keyword(s):  
Risk Factors ◽  
Oral Cavity ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Wide Spectrum ◽  
Malignant Lesion ◽  
Histopathological Diagnosis ◽  
Cross Sectional ◽  
Gold Standard Method ◽  
Clinical Diagnoses

Introduction: Oral cavity lesions comprise a wide spectrum of diseases that varies from non-neoplastic to neoplastic. The clinical evaluation alone is insufficient for proper diagnosis in most cases. So, histopathological examination is the gold standard method for diagnosis and management of patients accordingly. Objective: The present study was done to evaluate the histopathological spectrum of oral cavity lesions and compare them in relation to age, sex, site, clinical features, risk factors, and clinical diagnoses. Methods: This prospective cross-sectional study enrolled 127 cases of oral biopsies which were received at the Department of Pathology, Tribhuvan University and Teaching Hospital, Kathmandu Nepal, from May 2018 to April 2019 for histopathological examination. Specimens were fixed in 10% formalin and subjected for tissue processing and Hematoxylin and Eosin stained sections. Data entry and analysis were done by using SPSS 24 version where frequency and percentile were calculated. Results: Total cases were 127 with slight female predilection and the age group of 50-60 years (mean age of 44.24 years) were commonly affected. The tongue being the most common site, frequently lesions presented as swelling. Most of the lesions were non-neoplastic comprising 45% whereas malignant lesions comprised 23.6%. Smoking increased the risk of malignancy by 2 fold. The most common benign lesions were squamous papilloma & fibroepithelial polyp whereas the malignant lesion was squamous cell carcinoma. Sixty percent of clinical diagnoses didn’t show correlation. Conclusions: Oral cavity lesions have a wide spectrum of distribution in age, sex, site, and clinical presentation. Initially, oral lesions may present with subtle symptoms which may cause underdiagnosis. Thus, histopathological diagnosis is a must to rule out malignancy. Keywords: Clinical presentation; correlation; oral cavity; risk factors.

scholarly journals Leiomyosarcomna Presenting as Abdominal Pain in a 50 Years Old Woman: A Case Report

1970 ◽  
Vol 2 (1) ◽  
pp. 32-35
Author(s):  
Md Tahminur Rahman ◽  
SS Ahmed
Keyword(s):  
Abdominal Pain ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Menopausal Woman ◽  
Histopathological Diagnosis ◽  
Dysfunctional Uterine Bleeding ◽  
Medical College ◽  
Persistent Abdominal Pain ◽  
Key Words Leiomyosarcoma ◽  
Post Menopausal

Leiomyosarcoma of uterus is a comparatively rare tumor we come across in daily histopathological examination. Clinical presentation of a leiomyosarcoma is varied and includes dysfunctional uterine bleeding, abdominal distention, abdominal pain and metastatic symptoms depending on the organ involved like Lung, bone and brain. Here we report a case of leiomyosarcoma in a 50 year old woman having a single complain of persistent abdominal pain for last 1 year or so. Clinically and by ultrasonogram it was diagnosed as a case of large fibroid. Subsequent histopathological diagnosis was leiomyisarina. Any post menopausal woman having persistent abdominal pain and a clinical and USG diagnosis of fibroid a differential of leiomyosarcoma should be borne in mind of the physicians. Key Words: Leiomyosarcoma; Abdominal Pain DOI: 10.3329/akmmcj.v2i1.7469 Anwer Khan Modern Medical College Journal 2011; 2(1): 32-35

scholarly journals A Rare Case of Rhinofacial Zygomycosis due to Conidiobolus Infection

2014 ◽  
Vol 6 (2) ◽  
pp. 65-67 ◽  
Author(s):  
Arunabha Chakravarti ◽  
Meenakshi Mishra
Keyword(s):  
Rare Case ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Excellent Result ◽  
Histopathological Diagnosis ◽  
Immunocompetent Adult ◽  
Subcutaneous Tissues ◽  
Endoscopic Debridement ◽  
Multiple Drugs ◽  
Treatable Condition

ABSTRACT Background Rhinofacial zygomycosis is the infection of subcutaneous tissues of maxillofacial region caused by zygomycetes class of fungi. It is commonly caused by the order mucorales and is acute and fulminant. Infections by the order entomophthorales are rare but indolent. Case report We report an unusual case of rhinofacial zygomycosis due to Conidiobolus coronatus of the order Entomophthorales in an immunocompetent adult male to highlight the clinical presentation, diagnosis and treatment. We treated the patient with multiple drugs, that is amphotericin-B, cotrimoxazole, and itraconazole along with endoscopic debridement of nasal polyps with excellent result. Conclusion Rhinofacial zygomycosis due to entomophthorales is rare but treatable condition. Appropriate histopathological diagnosis and a multipronged approach with timely medical as well as surgical management is the key to clinical cure. How to cite this article Chakravarti A, Mishra M. A Rare Case of Rhinofacial Zygomycosis due to Conidiobolus Infection. Int J Otorhinolaryngol Clin 2014;6(2):65-67.

scholarly journals Skin Adnexal Tumors: A study of 26 cases

2020 ◽  
Vol 7 (11) ◽  
pp. A538-544
Author(s):  
Vidya Viswanathan ◽  
Arpana Dharwadkar ◽  
Shruti Vimal ◽  
Parul Bhandari ◽  
Aditi Malhotra ◽  
...  
Keyword(s):  
Prospective Study ◽  
Histopathological Examination ◽  
Single Case ◽  
Accurate Diagnosis ◽  
Histopathological Diagnosis ◽  
Clinical Correlation ◽  
Rare Tumours ◽  
Skin Biopsies ◽  
Benign Tumours ◽  
Adnexal Tumors

Background: Skin adnexal tumours are a category of rare tumours. They usually present as painless nodules and papules. The diagnosis of these tumours poses a challenge, because there is usually a discrepancy in clinical and histopathological diagnosis. Aims: To study the skin biopsies received in our department and compare their clinical and histopathological diagnosis. Material and methods: Prospective study of skin biopsies received in our department over a period of 1 year. The biopsies were processed and stained with haematoxylin and eosin and studied under the light microscope. Results: Out of the 26 cases studied, 25 were found to be benign tumours with a single case of keratoacanthoma. The most common tumour encountered was pilomatricoma and the least common was syringoma. Only four cases showed clinical correlation with histopathological diagnosis. Conclusion: It can be therefore concluded that skin adnexal tumours are rare tumours which need histopathological examination for their accurate diagnosis.

F.N.A.C. AS DIAGNOSTIC TOOL OF PAROTID TUMORS AND ASSOCIATED PITFALLS IN CORRELATION WITH HISTOPATHOLOGY

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Bhawana Pant ◽  
Sanjay Gaur ◽  
Prabhat Pant
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Clinical Information ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Cytological Diagnosis ◽  
Tertiary Referral Centre ◽  
Clear Cut ◽  
Parotid Tumors

F.NA.C has been used for ages as a safe and economical tool for fast preoperative diagnosis of parotid tumors. It has certain pitfall which sometimes leads to misdiagnosis and consequently it may have affect on treatment of the tumors. Keeping in view of the diverse classification of parotid tumors’ information from cytology should be combined with radiology as well as clinical diagnosis. Aim: To discuss some cases where there was discrepancy between cytological diagnosis and histopathological result and also suggest measures to improve the efficacy of F.N.A.C. Material and methods: The study includes 50 cases of parotid tumours who presented to the  department of ENT at Government medical college Haldwani which is a tertiary referral centre during 2009 to 2016. Only adult patients were included and inflammatory swelling were excluded from the study. All patients evaluated  Contrast enhanced computerized tomography(CECT) and  Magnetic resonance imaging (MRI) followed by Fine needle aspiration cytology .Preoperative diagnosis was made upon the findings of the above investigations and different types of  parotid surgeries  were done. . Final diagnosis was made on  histopathological  examination. Result :The most common tumour  came out to be pleomorphic adenoma (23 cases-46%) followed by mucoepidermoid carcinoma(12cases-24%). In ten  cases there was no clear cut  association between cytological diagnosis and final histopathological diagnosis. Conclusion: FNAC is highly sensitive and specific technique for diagnosis of many salivary gland swellings. FNAC can be used preoperatively to avoid unnecessary surgery and biopsy. Details of clinical information and radiologic features may help the pathologist to arrive at the appropriate diagnosis and reduce false interpretation. Pitfalls may also occur with improper technique of FNAC which can be overcome by proper caution.

Immunohistochemistry Particularities of Retroperitoneal Tumors

2018 ◽  
Vol 69 (7) ◽  
pp. 1813-1816 ◽  
Author(s):  
Ovidiu Gabriel Bratu ◽  
Radu Dragos Marcu ◽  
Bogdan Socea ◽  
Tiberiu Paul Neagu ◽  
Camelia Cristina Diaconu ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Histopathological Examination ◽  
Good Reason ◽  
Definitive Diagnosis ◽  
Histological Type ◽  
Not Given ◽  
Medical Specialties ◽  
Retroperitoneal Tumors ◽  
Extreme Variability ◽  
The One

Retroperitoneal space is called sometimes no man�s land�and for a good reason: this is disputed anatomical territory for many surgical and medical specialties. Their wide histological diversity and unspecific clinical presentation make them a challenge for the surgeon. In order to improve their detection immunohistochemistry seems to show promising results. Methods of detection have evolved over time to identify as much as possible the histological type of tumor. Because of this extreme variability immunohistochemistry through its various markers is the one that often sets the definitive diagnosis, the simple histopathological examination being insufficient. This paper aims to highlight the main markers used in retroperitoneal tumors. As it can be seen there is a huge histologic areal for these tumors. Some have proven some of them still not. Given the fact that there is a tendency toward personalized therapy it is imperative to identify the histological type of tumor as soon as possible.

Unusual case of soft palate and uvula haematoma in a patient on anticoagulant drugs

2020 ◽  
Vol 13 (12) ◽  
pp. e236513
Author(s):  
Stephanie Farrugia ◽  
Karl Sapiano ◽  
Robert Sciberras
Keyword(s):  
Atrial Fibrillation ◽  
Vitamin K ◽  
Soft Palate ◽  
Unusual Case ◽  
Sudden Onset ◽  
Anticoagulant Drugs ◽  
International Normalised Ratio ◽  
Oral Steroids

A 91-year-old Caucasian man on warfarin for atrial fibrillation presented in view of sudden-onset haemoptysis with fresh bleeding with clots immediately after having eaten a piping-hot traditional cheesecake (pastizz) and burning the soft-palate of his mouth. The haemoptysis had resolved by the time that the patient had arrived to hospital. On examination, a 2 cm by 2 cm dark red, solitary mass could be seen just anterior to the uvula. This was not causing any pain or discomfort to the patient. Blood results were mostly unremarkable except for a raised international normalised ratio (INR) of 3.53. The patient was administered 5 mg vitamin K orally in attempt to lower the INR level and warfarin was subsequently omitted for 7 days. He was also prescribed oral steroids on discharge. The lesion resolved in 7 days and warfarin was restarted then with no further consequences.

scholarly journals Pleomorphic Adenoma of the Submandibular Gland in a 10-Year-Old Child: A Case Report

2021 ◽  
pp. 014556132110221
Author(s):  
Bouatay Rachida ◽  
Ons Kharrat ◽  
Wiem Boughzala ◽  
Seifeddine Ben Hammouda ◽  
Nouha Ben Abdeljelil ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Preoperative Evaluation ◽  
Needle Aspiration ◽  
Magnetic Resonance Images ◽  
Fine Needle ◽  
Sebaceous Cyst ◽  
Growing Mass

We report the case of a 10-year-old girl with a painless slowly growing mass that had developed over the course of 2 years in the left submandibular area. Physical examination revealed a firm painless submandibular mass with no other associated signs. Ultrasound graphics were in favor of a sebaceous cyst. Fine-needle aspiration and magnetic resonance images (MRI) concluded to a pleomorphic adenoma of the submandibular gland. The patient underwent left submandibulectomy. Histopathological examination confirmed the diagnosis of pleomorphic adenoma arising from the submandibular gland. The postoperative course was uneventful. Pleomorphic adenoma of the submandibular gland represents a diagnostic and therapeutic dilemma in children. Preoperative evaluation, including MRI and fine-needle aspiration, is recommended. Total submandibulectomy is also recommended to minimize recurrences and to avoid malignant transformation.

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