scholarly journals Leiomyosarcomna Presenting as Abdominal Pain in a 50 Years Old Woman: A Case Report

1970 ◽  
Vol 2 (1) ◽  
pp. 32-35
Author(s):  
Md Tahminur Rahman ◽  
SS Ahmed
Keyword(s):  
Abdominal Pain ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Menopausal Woman ◽  
Histopathological Diagnosis ◽  
Dysfunctional Uterine Bleeding ◽  
Medical College ◽  
Persistent Abdominal Pain ◽  
Key Words Leiomyosarcoma ◽  
Post Menopausal

Leiomyosarcoma of uterus is a comparatively rare tumor we come across in daily histopathological examination. Clinical presentation of a leiomyosarcoma is varied and includes dysfunctional uterine bleeding, abdominal distention, abdominal pain and metastatic symptoms depending on the organ involved like Lung, bone and brain. Here we report a case of leiomyosarcoma in a 50 year old woman having a single complain of persistent abdominal pain for last 1 year or so. Clinically and by ultrasonogram it was diagnosed as a case of large fibroid. Subsequent histopathological diagnosis was leiomyisarina. Any post menopausal woman having persistent abdominal pain and a clinical and USG diagnosis of fibroid a differential of leiomyosarcoma should be borne in mind of the physicians. Key Words: Leiomyosarcoma; Abdominal Pain DOI: 10.3329/akmmcj.v2i1.7469 Anwer Khan Modern Medical College Journal 2011; 2(1): 32-35

scholarly journals Histopathological Analysis of Endometrial Biopsy in Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel
Keyword(s):  
Histopathological Examination ◽  
Hydatidiform Mole ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Medical College ◽  
Dilatation And Curettage ◽  
Partial Mole ◽  
Proliferative Endometrium ◽  
The Common

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.

scholarly journals Pelvic inflammatory disease by actinomyces: report of 1 case and review of the literature

2020 ◽  
Vol 9 (2) ◽  
pp. 804
Author(s):  
Cesar Giovanni Camacho Herrera ◽  
Raul D. Lara Sanchez ◽  
Narmy Olivera Garcia ◽  
Karla E. Abundiz Bibiano
Keyword(s):  
Abdominal Pain ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Intrauterine Device ◽  
Fibrous Tissue ◽  
Pain Syndrome ◽  
Exploratory Laparotomy ◽  
Abdominal Hysterectomy ◽  
Histopathological Diagnosis ◽  
Persistent Abdominal Pain

Actinomycosis is a chronic disease that is characterized by the formation of abscesses, fistulas and dense fibrous tissue at the site of involvement. Its distribution is worldwide. However, pelvic actinomycosis has increased in frequency and has been associated with abdominal surgery, intestinal perforation or trauma, due to the destruction of the muscular barrier. The clinical elements of suspicion are the latency of months and even years of symptoms and the history of being a carrier of an intrauterine device. Actinomyces israelli is a rare etiological agent of pelvic inflammatory disease, so it is difficult to reach the diagnosis. A case report is made of a 48-year-old patient with an intrauterine device older than 5 years, who entered the emergency department with abdominal pain syndrome and 7-day evolutionary fever accompanied by dyspareunia. She was hospitalized for antibiotic treatment, presenting an unsatisfactory evolution, with increased leukocytosis and persistent abdominal pain. An exploratory laparotomy with abdominal hysterectomy was performed. The histopathological diagnosis was pelvic inflammatory disease due to actinomyces. We must always suspect in the presence of a pelvic inflammatory disease in any of its clinical forms, the presence of actinomyces as one of the possible causative germs, especially in patients with intrauterine device for more than 5 years.

scholarly journals A retrospective clinico-pathological study of hysterectomy cases in a tertiary care hospital in India – a review of 950 cases.

2018 ◽  
Vol 17 (1) ◽  
pp. 88-92
Author(s):  
Pal Subrata ◽  
Chakrabarti Srabani ◽  
Sinha Anuradha ◽  
Phukan Jyoti Prakash ◽  
Bose Kingshuk ◽  
...  
Keyword(s):  
Clinical Diagnosis ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Medical Science ◽  
Abdominal Hysterectomy ◽  
Uterine Bleeding ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Dysfunctional Uterine Bleeding ◽  
Common Indication

Introduction: Hysterectomy is the most commonly performed gynaecological surgery in India as well as in abroad. It is frequently done in myometrial and endometrial pathologies and rarely for other causes. Hysterectomy is definitive management for diseases like fibroid, adenomyosis, dysfunctional bleeding, prolapsed uterus and malignant lesions of uterus and adenexa. We aimed our study to observe incidence of different pathologies of uterus and other reproductive organs in hysterectomy specimens and retrospective correlation between clinical diagnosis and histopathological finding of hysterectomy cases.Materials and Methods: Retrospective data were collected from our routine histopathological laboratory. Detailed history, clinical examination and operative findings and provisional diagnosis of all 950 hysterectomy cases were recorded during study period of 2 years. Histopathological diagnosis was correlated with clinical and preoperative diagnosis.Observations: Abdominal hysterectomy (734 cases, 77.26%) was the most common route of approach during surgery. Common pre-operative diagnoses were fibroid uterus (32%), dysfunctional uterine bleeding (28.95%), uterine prolapsed (22.74%). Other causes included uterine polyps (1.6%), complications of pregnancy (2.74%), ovarian tumours (8.42%), cervical carcinomas (2.97%) etc. Common pathologies on histology were leiomyoma (32%), adenomyosis (20.32%), atrophic endometrium (17.26%) and endometrial pathology (8.95%).Discussion: Our study has been correlated with other studies of India and other south Asian countries. Most common indication of hysterectomy in our study is dysfunctional uterine bleeding (32%) but Gupta et al and Jha R et al found utero-vaginal prolapse as most common indication. Leiomyoma was the most common histology diagnosed in the present series. Clinical diagnosis was possible in 67.57% cases in our study similar to Khan et al (70.51%).Conclusions: Histopathological examination of hysterectomy specimens helps to detect the exact causes and underlined pathology.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.88-92

A Clinicopathological Study of Various Conjunctival Lesions in Children

2016 ◽  
Vol 1 (4) ◽  
pp. 143-147
Author(s):  
Juhi Goel ◽  
Swapnila Prasad ◽  
Ashutosh Dokania
Keyword(s):  
Clinical Presentation ◽  
Histopathological Examination ◽  
Uttar Pradesh ◽  
Capillary Hemangioma ◽  
Treatment Modalities ◽  
Age Group ◽  
Pediatric Age ◽  
Medical College ◽  
Pediatric Age Group ◽  
Clinicopathological Study

ABSTRACT Conjunctival cysts are of a common occurrence in clinical parlance. These tend to be mostly asymptomatic. However, the underlying cause may be vision threatening. Thus, we conducted a clinicohistopathological study of conjunctival cysts in pediatric age group who presented to our outpatient department in Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, India. The aim was to analyze the risk factors, clinical presentation, treatment modalities, and a certain type of cysts in order of their frequency. Significant history, detailed ocular examination, and relevant investigations that were carried out in 10 cases of conjunctival lesions were noted. The management was done and the histopathological examination (HPE) reports were charted. Despite a similar clinical presentation, HPE revealed varied diagnosis. These comprised choristomatous cysts (4), subconjunctival cysticercosis (2), inclusion cysts (2), inflammatory cyst (1), and capillary hemangioma (1). Conjunctival cysts are not just a cosmetic blemish. A detailed ocular examination, early diagnosis, and treatment can help prevent various vision-threatening complications. How to cite this article Goel J, Prasad S, Dokania A. A Clinicopathological Study of Various Conjunctival Lesions in Children. Int J Adv Integ Med Sci 2016;1(4):143-147.

scholarly journals Benign myoepithelioma of the soft palate: an unusual clinical entity

2021 ◽  
Vol 14 (6) ◽  
pp. e240384
Author(s):  
Marianna Guadalupe Mireles ◽  
Angelica Julián ◽  
Fabiola Salgado-Chavarría ◽  
Guillermo Manuel González
Keyword(s):  
Soft Palate ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Histopathological Diagnosis ◽  
Exocrine Glands ◽  
Present Case Report ◽  
Common Location ◽  
Benign Tumours ◽  
Growing Mass

Myoepitheliomas are rare benign tumours that affect the exocrine glands and are sporadically located in the salivary glands. The most common location of myoepithelioma in the oral cavity is the parotid gland and it is seldom encountered in the palate. The diagnosis of this entity is challenging since its clinical presentation may resemble those of more common neoplasms, rendering a complex histopathological diagnosis. The aim of the present case report is to describe an unusual case of myoepithelioma of the soft palate in a male patient, which developed as an asymptomatic, slowly growing mass. The tumour was assessed with histopathological examination and the diagnosis was verified via immunohistochemistry. Finally, the treatment included surgical resection of the tumour and no signs of recurrence were noted 2.5 years after the surgical procedure. Early diagnosis and treatment plays an important role in the prognosis of this pathological entity.

scholarly journals Rare case of gastrointestinal bleeding: jejunal gastrointestinal stromal tumor

2021 ◽  
Vol 8 (3) ◽  
pp. 1041
Author(s):  
Sahana Muniramu ◽  
Madavan Praveena ◽  
Aparajita Mookherjee ◽  
Bommareddy Akhila ◽  
Subhodaya Reddy
Keyword(s):  
Rare Case ◽  
Histopathological Examination ◽  
Menopausal Woman ◽  
Proximal Jejunum ◽  
Gastrointestinal Stromal Tumours ◽  
Post Menopausal Woman ◽  
Postoperative Course ◽  
Pain Abdomen ◽  
Post Menopausal ◽  
Operative Findings

Gastrointestinal stromal tumours (GIST) are mesenchymal or non-epithelial neoplasms of gastrointestinal tract, with most common GI location being stomach (60%), followed by small intestine (30%), colon, rectum and oesophagus. Occurrence of GIST in jejunum is rare. Here we report a rare case of a 45 years old post-menopausal woman with pain abdomen, vomiting, malena and anemia who underwent laparotomy with resection of the tumour and anastomosis. Intra-operative findings revealed a 10x8 cms exophytic mass at the mesenteric end of the proximal jejunum, 10 cms from the DJ flexure. Diagnosis was confirmed by histopathological examination and immunohistochemistry (CD117). Patient had an uneventful postoperative course.

Premalignant and Malignant Changes in Symptomatic Endometrial Polyps in Women Aged 20-70 years

2018 ◽  
Vol 9 (4) ◽  
Author(s):  
Susan Abed Zaidan ◽  
Alaa Abdulqader Abdulrazaq ◽  
Eaman Marouf Muhammed
Keyword(s):  
Histopathological Examination ◽  
Abnormal Uterine Bleeding ◽  
Common Finding ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Endometrial Polyps ◽  
Malignant Changes ◽  
Post Menopausal ◽  
Malignant Polyps

Background: endometrial polyps are localized over growth of endometrium including glandular and stromal tissue with prominent angiogenesis regulated by growth factors. Polyps occur in different age group and could be asymptomatic and discovered incidentally or it cause abnormal premenopausal and postmenopausal bleeding. Most endometrial polyps are benign but premalignant and malignant changes also occur frequently. Objective: this study was carried out to identify the age-group in which endomaterial polyps are encountered in routine surgical pathology practice, to document the agegroup in which these polyps underwent malignant changes and to identify the histological subtype of endometrial polyps according to age group. Patients and methods: This prospective study conducted to demonstrate the premalignant and malignant changes in symptomatic endometrial polyps in relation to patients age group ranging from 20-70 years with abnormal uterine bleeding examined in gynecology and obstetric department in Al-Ramadi and Al-Yarmouk Teaching Hospital during the period from January 2017 to May 2018. The endometrial samples were obtained either by D and C, hysteroscopy or the polyps were demonstrated after surgical hysterectomy. All endometrial samples were fixed in 10% formalin solution and sent to the private histopathology laboratory in Baghdad for histopathological diagnosis. Results: The total number of examined women were 150. The most common recorded age was 20-70 years. 74.6% were premenopausal and 25.4% of patients were post-menopausal at the time of diagnosis. Most of patients presented with symptomatic polyps in this study were in age group 41-50 years (36.6%) in which most of the polyps were benign, while premalignant and malignant changes were more common in women between 51-60 years. The final pathological diagnoses showed benign endometrial polyps (49.3%), (48.6%) were pre-malignant polyps and (2 %) were malignant polyps. From benign lesions secretary endometrium was the most common finding in 43 cases (58.1%), while simple endometrial hyperplasia without atypia was the most common finding in the pre-malignant group 40 cases (54.7%). The distribution of histopathological changes in each age group were significant with a P value equal to 0.02. Conclusion: all endometrial polyps in pre- and post-menopausal women should be removed and submitted for histopathological examination as some of them even though there are benign but could carry areas of cellular atypia or malignant transformation.

scholarly journals A Rare Case of Primary Lymphoma of the Caecum Presenting as Intussusception

2013 ◽  
Vol 5 (02) ◽  
pp. 118-120 ◽  
Author(s):  
Leena Jayabackthan ◽  
Sandeep Babukumar Murgi ◽  
Shane Graham ◽  
Reshma G Kini
Keyword(s):  
Abdominal Pain ◽  
Therapeutic Strategy ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Primary Lymphoma ◽  
Emergency Laparotomy ◽  
Lead Point ◽  
Ileocolic Intussusception ◽  
Mild Abdominal Pain ◽  
The Right

ABSTRACTMucosa associated lymphoid tissue (MALT) lymphomas are rare neoplasms. They are most common in the stomach followed by small intestine and colon. The symptoms are nonspecific and generally do not present with intussusception. Here we report a rare clinical entity in which a 35-year-old female presented to the emergency with severe abdominal pain which was sudden in onset. History revealed that she had been having vague mild abdominal pain for 2 years. Ultrasonography showed ileocolic intussusception with hypoechoic lesion of 54 x 46 mm seen at the lead point. Emergency laparotomy with the right hemi-colectomy was done. The specimen was sent for histopathological examination which revealed a diagnosis of MALT lymphoma. Awareness of the varied clinical presentation helps in formulating the appropriate therapeutic strategy.

scholarly journals Rhabdomyosarcoma of the Cervix in a Post-Menopausal Woman—An Unparalleled Phenomenon

2021 ◽  
Vol 18 (15) ◽  
pp. 7851
Author(s):  
Jakub Pawlik ◽  
Weronika Pawlik ◽  
Dorota Branecka-Woźniak ◽  
Katarzyna Kotrych ◽  
Aneta Cymbaluk-Płoska
Keyword(s):  
Treatment Guidelines ◽  
Histopathological Examination ◽  
Embryonal Rhabdomyosarcoma ◽  
Surrounding Tissue ◽  
Menopausal Woman ◽  
Fallopian Tubes ◽  
Resonance Imaging ◽  
Palpable Mass ◽  
Post Menopausal

Rhabdomyosarcoma of the cervix is a soft tissue sarcoma that usually occurs in young women. It is very rare in adulthood. We discuss symptoms, the process of diagnosis of rhabdomyosarcoma embryonale of the cervix in a 61-year-old women and differences in treatment dependent on patient’s age. A 61-year-old woman with symptoms such as palpable mass in the external cervical opening and post-menopausal hemorrhaging was admitted to the oncology ward where excision of the polyp was performed. Embryonal rhabdomyosarcoma (ERMS) was diagnosed by histopathological examination of obtained tissues. The diagnosis was complemented by chest computed tomography and pelvis magnetic resonance imaging to exclude metastases. A Wertheim–Meigs operation and excision of the ovaries, the fallopian tubes and the surrounding tissue was performed in the course of treatment. In the patient’s follow-up of 25 months to date, there have been no signs of recurrence or symptoms connected to ERMS. Based on the therapeutic outcome, the decision to limit the treatment to a surgical resection was adequate for a post-menopausal patient. Because of the rarity of ERMS in the post-menopausal age, we think that the patient should be carefully followed up to further examine this issue and develop diagnostic and treatment guidelines.

scholarly journals HYSTERECTOMIES

2011 ◽  
Vol 18 (01) ◽  
pp. 46-50
Author(s):  
QAMAR-UR- NISA ◽  
HABIB ULLAH ◽  
TANWEER AHMED SHAIKH ◽  
Miss Hemlata ◽  
Fatima Memon ◽  
...  
Keyword(s):  
Coming Out ◽  
Histopathological Examination ◽  
Medical College Hospital ◽  
Uterovaginal Prolapse ◽  
Histopathological Diagnosis ◽  
College Hospital ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Chronic Cervicitis ◽  
Made In

Objective: To audit indications and histopathological diagnosis of hysterectomies performed at Muhammad Medical College hospital, Mirpurkhas. Study Design: Retrospective study. Place and Duration of Study: Department of Obstetrics and Gynaecology and Department of Pathology, Muhammad Medical College Hospital, Mirpurkhas Sindh from January to December 2008. Methodology: Data regarding symptoms and indications of hysterectomies performed during this year were collected from files and patient records. Histopathological reports of those patients were collected from department of pathology. The results were analyzed by percentages. Results: A total of 145 hysterectomies were performed in 2008. Mean age of patients was 45years ranging from 35-60 years and parity ranges from 4 – 10. Most common presenting complaints were excessive menstrual blood loss in 97(67%) patients, followed by some thing coming out of vagina 28(19%). Most common pre-operative diagnosis of fibroid was made in 44 (33%) followed by uterovaginal prolapse in 28(19%) and dysfunctional uterine bleeding (DUB) in 18(12%) of patients. Regarding histopathological diagnosis chronic cervicitis was the most commonly diagnosed pathology in 45 (31%) followed by fibroid in 25(17%) cases. Conclusions: A yearly audit should be conducted in every institute to collect data and to analyze the pattern of indication and lesions found on histopathological examination. 

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