Is percutaneous glue injection one of the treatments for arteriovenous malformation pinna?

2021 ◽  
Vol 14 (5) ◽  
pp. e242103
Author(s):  
Sauradeep Das ◽  
Saranya Thangavel ◽  
Arun Alexander ◽  
Nagarajan Krishnan
Keyword(s):  
Arteriovenous Malformation ◽  
Head And Neck ◽  
Surgical Resection ◽  
Genetic Mutations ◽  
Precipitating Factors ◽  
Hormonal Influence ◽  
Rare Phenomenon ◽  
Feeding Vessels ◽  
Glue Injection

Arteriovenous malformation (AVM) of the head and neck is a rare phenomenon, more so when it is an extracranial AVM like the auricle. AVMs are caused by genetic mutations. Most are probably present in the subclinical form at birth and then evolve; some may arise postnatally or during adolescence or get aggravated by precipitating factors like trauma, infection or hormonal influence like puberty or pregnancy. Once diagnosed, the feeding vessels have to be identified using radiological investigations. They are then embolised via means of percutaneous embolisation and surgical resection.

scholarly journals Techniques of Onyx Embolization of Arteriovenous Malformation: 2-Dimensional Operative Video

2021 ◽  
Author(s):  
Kathryn M Wagner ◽  
Visish M Srinivasan ◽  
Peter Kan
Keyword(s):  
Informed Consent ◽  
Surgical Resection ◽  
Arteriovenous Malformations ◽  
Preoperative Embolization ◽  
Great Care ◽  
Endovascular Techniques ◽  
Definitive Therapy ◽  
Feeding Vessels ◽  
Multiple Feeding ◽  
Staged Treatment

Abstract Advances in endovascular techniques and tools have allowed for treatment of complex arteriovenous malformations (AVMs), which historically may have posed unacceptable risk for open surgical resection. Endovascular treatment may be employed as an adjunct to surgical resection or as definitive therapy. Improvements in embolization materials have made endovascular AVM treatment safer for patients and useful across a variety of lesions. While many techniques are employed for transarterial AVM embolization, the essential tenets apply to all procedures: (1) great care should be taken to cannulate only vessels directly supplying the lesion, and not en passage vessels, prior to injecting embolisate; (2) embolisate should travel into the nidus, but not into the draining veins; (3) embolistate reflux proximal to the microcatheter should be avoided. There are several techniques that accomplish these goals, including the plug and push method, or using a balloon to prevent embolisate reflux. We use controlled injection of liquid Onyx (Medtronic), with increasing pressure over multiple injections pushing the embolisate forward into the AVM. This is repeated in multiple feeding vessels to decrease or eliminate supply to the AVM. Here, we present a 36-yr-old female with a right parietal AVM discovered on workup of headaches. After informed consent was obtained, she underwent preoperative embolization using this technique prior to uncomplicated surgical resection. The video shows the endovascular Onyx embolization of multiple feeding vessels over staged treatment.

scholarly journals Neoadjuvant immunotherapy in resectable head and neck cancer: oral cavity carcinoma as a potential research model

2021 ◽  
Vol 13 ◽  
pp. 175883592098406
Author(s):  
Vanesa Gutiérrez Calderón ◽  
Alexandra Cantero González ◽  
Laura Gálvez Carvajal ◽  
Yolanda Aguilar Lizarralde ◽  
Antonio Rueda Domínguez
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Surgical Resection ◽  
Squamous Cell ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
Research Model

Squamous cell carcinoma of oral cavity (OCSCC) accounts for approximately 25% of cases of head and neck squamous cell carcinoma (HNSCC). Tobacco and alcohol consumption are the main risk factors for both cancers. Surgical resection, combined with adjuvant radiotherapy or radiochemotherapy in patients with high risk of relapse, is the key element in management in the initial stages. However, despite the availability of aggressive multidisciplinary treatments, advanced resectable OCSCC carries poor prognosis; only half of the patients are disease-free 5 years after the surgery. Immunotherapy based on the use of immune checkpoint inhibitors has been proven to be effective in a wide variety of tumours, including recurrent and metastatic HNSCC. These positive results resulted in investigations into its effectiveness in earlier stages of the disease with OCSCC emerging as an interesting research model because of the accessible location of the tumours. This article reviews the potential advantages of emerging immunotherapeutic agents [mainly monoclonal antibodies against programmed cell death-1 ( PD-1) immune checkpoint inhibitors] as neoadjuvant treatment for OCSCC at locoregional stages as well as the ongoing clinical trials, challenges in evaluating tumour response, and possible predictive biomarkers of response with highlights regarding the role of oral microbiota as modulators of immune response. The efficacy and safety of anti- PD-1 drugs in these patients have been proven in preliminary trials. If there is a decrease in the relapse rate and an improvement in the overall survival after surgical resection in ongoing trials, preoperative immunotherapy may be established as a treatment option for patients with early stages of the disease.

Congenital arteriovenous malformation of the head and neck

1978 ◽  
Vol 136 (4) ◽  
pp. 424-429 ◽  
Author(s):  
John D. DesPrez ◽  
Clifford L. Kiehn ◽  
Catherine Vlastou ◽  
Charles Bonstelle
Keyword(s):  
Arteriovenous Malformation ◽  
Head And Neck ◽  
Congenital Arteriovenous Malformation

431 Surgical resection of pulmonary metastases from head and neck cancer

Lung Cancer ◽  
1997 ◽  
Vol 18 ◽  
pp. 111
Author(s):  
T. Iwata ◽  
K. Inoue ◽  
T. Kato ◽  
T. Nishida ◽  
K. Konishi ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Surgical Resection ◽  
Neck Cancer ◽  
Pulmonary Metastases

scholarly journals Mucosal Melanoma of the Head and Neck: Tata Memorial Hospital Experience

2010 ◽  
Vol 1 (3) ◽  
pp. 141-145 ◽  
Author(s):  
Vedang Murthy ◽  
Ashwini Budrukkar ◽  
Gupta Tejpal ◽  
Jai Prakash Agarwal ◽  
Suruchi Singh ◽  
...  
Keyword(s):  
Head And Neck ◽  
Surgical Resection ◽  
Adjuvant Radiotherapy ◽  
Disease Free Survival ◽  
Mucosal Melanoma ◽  
Locoregional Control ◽  
Free Survival ◽  
Tata Memorial Hospital ◽  
Aggressive Tumor ◽  
Disease Free

Abstract Background Primary mucosal melanoma of the head and neck (MMHN) is a rare, aggressive tumor of neural-crest origin. Despite universal progress in cancer care, the prognosis of MMHN continues to remain dismal. Aims To analyze and report the outcomes of primary head and neck mucosal melanomas treated at Tata Memorial Hospital. Methods Retrospective chart review of all patients with a diagnosis of nonocular MMHN presenting to the institute between 1995 to 2003. Locoregional control and disease-free survival were used as outcome measures. Results 42 patients presenting within the study period with nonocular MMHN (oral-55%, sinonasal-40%, and pharyngeal-5%) at a median age of 53 years constituted the demographic cohort. 11 (26%) patients not amenable to any active anticancer treatment were treated with best supportive care alone and excluded from outcome analysis. 26 patients underwent surgery with complete resection of tumor. Seven (27%) also received adjuvant radiotherapy due to the adverse histopathologic features. Two patients were treated with radical radiotherapy due to unresectability, two patients received palliative chemotherapy, while one patient was treated with definitive chemoradiotherapy. With a mean follow-up of 11 months (range 1-58 months), the 3-year locoregional control and disease-free survival was 41% and 12% respectively. Age, sex, site of primary, tumor stage, surgical resection, margin status, depth of infiltration, and adjuvant radiotherapy did not affect outcome significantly. Conclusion Primary mucosal melanoma of the head and neck is a rare, but, aggressive tumor with a dismal prognosis. Surgical resection with clear margins offers the best chance of cure for early localized disease. The high incidence of locoregional as well as distant failures after surgical resection supports the use of adjuvant therapy. Deeper insights into the pathobiology of disease can help develop more specific and effective treatment strategies to improve long-term outcomes.

scholarly journals ROLE OF ACCESS OSTEOTOMY IN HEAD AND NECK LESIONS – A REVIEW

2021 ◽  
pp. 25-30
Author(s):  
BHARATHI K ◽  
MANOJ CHANDRASEKAR ◽  
KAPIL DEV KUMAR S ◽  
BALA JAGANNATH GUPTA B
Keyword(s):  
Head And Neck ◽  
Surgical Resection ◽  
Hand Search ◽  
Surgical Access ◽  
Operative Care ◽  
Specific Tumor ◽  
Surgical Field ◽  
Tumor Types ◽  
Neurovascular Structures

The surgical resection of the head and neck lesions summarizes the principles, classifications, applications, complications, and post-operative care of osteotomy with the standard protocols performed safely. It often poses a great surgical challenge due to the anatomical complexity, difficulty in accessibility, and proximity of vital structures. A multidisciplinary approach is often required in these situations for their better exposure to provide surgical access. Access osteotomy is the choice and type for these head and neck lesions, which are most often based on the anatomic extent of the lesion, vascularity of the lesion, and involvement of neurovascular structures in and around it. The literature search using Medline from the year 1986 to 2019 were performed and textbooks were also collected by hand search from the same period. The role of aggressive surgical resection has not been established for malignant head and neck lesions with the technical feasibility and its efficacy for specific tumor types must be defined by the future studies. Thus, we would like to conclude that access osteotomy allows the surgeon a better view and an access of the surgical field to resect the tumor completely with safer margins, preserving the vital structures, pre-operative functions, and reducing post-operative complications.

scholarly journals The Rare Cases of Parotid Gland Arteriovenous Malformations

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Manish Gupta ◽  
Vijay Shrawan Nijhawan ◽  
Cynthia Kaur ◽  
Sukhpreet Kaur ◽  
Akanksha Gupta
Keyword(s):  
Parotid Gland ◽  
Arteriovenous Malformation ◽  
Head And Neck ◽  
Arteriovenous Malformations ◽  
Neck Region ◽  
Histopathological Study ◽  
Head And Neck Region ◽  
Parotid Region ◽  
Venous Circulation ◽  
Patient Setup

Arteriovenous malformation (AVM) results from errors in vascular development during embryogenesis; absent capillary beds lead to shunting directly from the arterial to venous circulation. Although it is common in the head and neck region, AVMs located in the parotid gland are quite rare. Here, we report two cases of arteriovenous malformation of the parotid gland that presented to our out-patient setup with swelling in the parotid region and were diagnosed as arteriovenous malformation on histopathological study after surgical resection.

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