Topical medication as an initial therapeutic option for protruding and non-protruding condylomata acuminata of the distal urethra

2021 ◽  
Vol 14 (9) ◽  
pp. e243618
Author(s):  
Tomislav Mestrovic ◽  
Mario Sviben ◽  
Sanja Zember ◽  
Domagoj Drenjancevic

Genital warts (also known as condylomata acuminata) caused by the human papillomavirus (HPV) represent one of the most common sexually transmitted infections. Although they are usually found in the outer genital region, a small proportion of men can present with (often unrecognised) intraurethral warts, generally limited to the distal urethra and urethral meatus. This poses a treatment challenge not adequately addressed by the current guidelines. Here, we present two cases of low-risk HPV-positive patients with protruding and non-protruding condylomata acuminata of the distal urethra, which were treated successfully by using two different topical regimens (ie, a combination of policresulen and imiquimod for one patient and 5-fluorouracil monotherapy for the other). Although this type of management results in lower rates of tissue destruction and complications and may be given preference as an initial therapeutic option, additional prospective comparative clinical studies are needed to elucidate its potential in similar cases.

2012 ◽  
Vol 23 (7) ◽  
pp. 512-515 ◽  
Author(s):  
E M Van Der Snoek ◽  
A M Van Loon ◽  
A M Lammers ◽  
S M Couwenberg

Genital warts are one of the most prevalent sexually transmitted infections in the Netherlands and cause both frustration and misinterpretation in young adults. Poor knowledge may be associated with shame and depression. We used questionnaires to study knowledge, perceived nuisance and risk perception in 100 predominantly heterosexual men with clinically-confirmed condylomata acuminata. Our data show that the majority of patients considered having warts as (very) bothersome. Results confirmed the Internet as a widely used information source. Incorrect information on the relationship between warts and both anogenital cancers and infertility was widespread. Results from knowledge questionnaires showed that higher knowledge scores were associated with higher perceived nuisance. We hypothesize that high levels of nuisance related to genital warts may stimulate the need to seek information and therefore increase knowledge. It does not seem likely that an increase of human papillomavirus-related knowledge would increase experiences of nuisance.


2021 ◽  
pp. 603-628
Author(s):  
Henrietta Williams

Why are sexually-transmitted infections important??, Syndromic management of sexually-transmitted infections?, Syphilis?, Gonorrhoea?, Chlamydial infections?, Chancroid?, Granuloma inguinale donovanosis?, Trichomoniasis?, Bacterial vaginosis?, Genital herpes?, Candida vaginitis?, Human papillomavirus and genital warts?


2021 ◽  
Vol 2 (3) ◽  
pp. 42-45
Author(s):  
Marco Ghezzi ◽  
◽  
Alberto Cescato ◽  
Giovanni Bisonni ◽  
Edoardo Albertin ◽  
...  

Human Papillomavirus (HPV) infection is one of the most common sexually transmitted condition in both genders and is responsible for penile, oral, neck and anal cancers in men. However, seminal HPV infection may contribute to the risk of male infertility.


Author(s):  
Panteha Tavassol ◽  
Naweed Ahmed ◽  
Wakqas Kayani ◽  
Sahab Jamshidi ◽  
Suneil Bapat ◽  
...  

Human papillomavirus (HPV) is one of the most common sexually transmitted infections. There are four common HPV strains: 6, 11, 16, and 18. Strains 6 and 11 cause genital warts, while strains 16 and 18 are asymptomatic in males and may progress to cervical cancer in females. Although uncommon, a small percentage of males and females have been diagnosed with HPV without previous sexual contact. In this case report, we discuss a case conducted on a 15-year-old South Asian male who contracted an unknown low-risk strain of HPV with no history of sexual contact. HPV is highly infectious, however in the majority of cases the immune system is able to clear the infection, preventing the appearance of genital warts. In cases such as these, it is important to help control the spread of viral infections. Several determinants of health are involved in and affect the transmission of HPV, including income and social status, social support networks, education and literacy, culture, social and physical environments, and health services. To aid in the prevention of HPV, sexual education should be taught at early ages within schools and the Gardasil® vaccine should be administered to both females and males at an early age to reduce the burden of disease and the incidence of HPV.


2019 ◽  
Vol 31 (4) ◽  
pp. 131-137
Author(s):  
Alyce Lima Amorim ◽  
Ana Gabriela Álvares Travassos ◽  
Geovane Cruz de Souza ◽  
Vitor Cunha Fontes ◽  
Maiara Timbó ◽  
...  

Introduction: Ureaplasma urealyticum and Mycoplasma hominis are frequently found at many women’s and men’s urogenital tract, and have been associated with non-gonococcal urethritis, cervicitis, infertility, chorioaminionitis and adverse pregnancy outcomes. Some studies show high prevalence of human papillomavirus (HPV) in patients with non-gonococcal urethritis, while also presenting high frequency of Ureaplasma urealyticum infection in women with cervicalcytology abnormalities and men with genital warts. Objectives: To evaluate the prevalence of Ureaplasma urealyticum, Mycoplasma hominis and HPV coinfection in people attending a sexually transmitted infections (STI)/HIV reference centre and to identify the risk factors associated. Methods: A cross-sectional study with patients aged >18 years, carried out for Ureaplasma urealyticum and Mycoplasma hominis from July 1st to December 31, 2015, in a STI/HIV reference centre from the State of Bahia, Brazil. Sociodemographic and clinical data were obtained from secondary data from patients’ charts and laboratory findings, and analyzed using SPSS 20.0. Pearson’s χ2 test or Fisher’s exact test was used to evaluate categorical variables. HPV clinical diagnosis was considered positive as the presence of genital warts. Results: In this study, 849 patients were included — 196 men and 653 women. Of the sample, 51.4% was diagnosed with at least one of the two bacteria. The prevalence of Mycoplasma hominis infection was higher in coinfection (16.7%) than in isolated infection (2.2%). The prevalence of Ureaplasma urealyticum isolated infection was 32.4%. A strong association was found between the presence of genital warts and Ureaplasma urealyticum infection, with an estimated risk of 1.230 (p=0.014). Conclusion: Our findings suggest the need for further investigation for Ureaplasma urealyticum infection in patients presenting genital warts on physical examination. In addition, in this context, greater attention should be given to women and pregnant women.


2020 ◽  
Author(s):  
Alexandria Richards ◽  
Joanna Stacey

Human papillomavirus, or HPV, is a common sexually transmitted disease, most often acquired during the adolescence or the early 20s. It can be divided into oncogenic and nononcogenic serotypes. It is responsible for genital warts as well as pathologic diseases that can lead to genital cancers and cancers of the oropharyngeal tract in both males and females. The majority of adolescents who acquire HPV infections do not go on to develop cancer. New discoveries about the virus’ persistence and latency direct how we treat adolescents with HPV infections. Recommendations for prevention of HPV include use of the 9-valent vaccine against the most common oncogenic HPV serotypes. Screening should be delayed until the age of 21, with the exception of immunocompromised women. The HPV vaccination is safe and effective, and does not encourage sexual activity among adolescents. Both boys and girls should be vaccinated against HPV at 11 to 12 years of age but may receive the vaccination as early as 9 or as late as 21 (males) or 26 (females) years of age. The vaccine may now also be given in only two doses if the series was started before the age of 15. Follow-up studies in the years after the vaccine’s introduction have shown large decreases in HPV infection rates. This review contains 7 figures, 7 tables and 63 references Key Words: Oncogenic subtype, Oropharyngeal cancer, Infection persistence, Immune tolerance, Cervical dysplasia, Genital warts, 9-valent vaccine, Vaccine safety  


2020 ◽  
pp. 25-29
Author(s):  
Anh Mai Ba Hoang ◽  
Duy Bui Van ◽  
Vy Vo Tuong Thao ◽  
Thanh Duong Huu ◽  
Nam Tran Ngoc Khanh

Background: Sexually transmitted diseases are popular, not only affecting the health but also affecting the psychology and social behavior of patients. After being diagnosed, the patients were hospitalized at the Department of Dermatology, Hue Central Hospital. Therefore, we conducted this study to investigate some characteristics of sexually transmitted diseases. Materials and methods: Cross-sectional study on 72 patients having one of sexually transmitted diseases,we investigated some characteristics and clinical forms. Results: The proportion of male and female was the same and the most common age group was 15-25 with 44.4%. Most patients had two or more sexual partners with 62.5% and very few often used condoms. Only three diseases were diagnosed with genital warts, syphilis and urethritis; among them genital warts was the most common 66.7%. Latent syphilis and small papules were the most common clinical forms of syphilis, condylomata acuminata, respectively. Conclusion: Sexually transmitted diseases were relatively common among inpatient diseases and had diverse characteristics. Keywords: sexually transmitted diseases, gonorrhea, syphilis, condylomata acuminata


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