scholarly journals Long covid: research must guide future management

BMJ ◽  
2021 ◽  
pp. n3109
Author(s):  
Anthony S David
Keyword(s):  
2019 ◽  
Vol 53 (5) ◽  
pp. 399-416
Author(s):  
V. M. Tytar ◽  
Ya. R. Oksentyuk

Abstract In this study an attempt is made to highlight important variables shaping the current bioclimatic niche of a number of mite species associated with the infestation of stored products by employing a species distribution modeling (SDM) approach. Using the ENVIREM dataset of bioclimatic variables, performance of the most robust models was mostly influenced by: 1) indices based on potential evapotranspiration, which characterize ambient energy and are mostly correlated with temperature variables, moisture regimes, and 2) strong fluctuations in temperature reflecting the severity of climate and/or extreme weather events. Although the considered mite species occupy man-made ecosystems, they remain more or less affected by the surrounding bioclimatic environment and therefore could be subjected to contemporary climate change. In this respect investigations are needed to see how this will affect future management targets concerning the safety of food storages.


2020 ◽  
Vol 27 (12) ◽  
pp. 1276-1287
Author(s):  
Brigida Anna Maiorano ◽  
Giovanni Schinzari ◽  
Sabrina Chiloiro ◽  
Felicia Visconti ◽  
Domenico Milardi ◽  
...  

Pancreatic neuroendocrine tumors (PanNETs) are rare tumors having usually an indolent behavior, but sometimes with unpredictable aggressiveness. PanNETs are more often non-functioning (NF), unable to produce functioning hormones, while 10-30% present as functioning (F) - PanNETs, such as insulinomas , gastrinomas , and other rare tumors. Diagnostic and prognostic markers, but also new therapeutic targets, are still lacking. Proteomics techniques represent therefore promising approaches for the future management of PanNETs. We conducted a systematic review to summarize the state of the art of proteomics in PanNETs. A total of 9 studies were included, focusing both on NF- and F-PanNETs. Indeed, proteomics is useful for the diagnosis, the prognosis and the detection of therapeutic targets. However, further studies are required. It is also warranted to standardize the analysis methods and the collection techniques, in order to validate proteins with a relevance in the personalized approach to PanNETs management.


2021 ◽  
pp. 237929812199705
Author(s):  
Joseph G. Gerard ◽  
Reena E. Lederman ◽  
Jack P. Greeley

As business and management instructors, we increasingly struggle with student inattention to information accuracy and quality in our courses, especially when student-based research is required and misinformation is more prevalent. Without the time to teach information literacy (IL) skills, we created a series of information sourcing (IS) prompts that were small and flexible enough to be deployed anywhere we might need IL reinforcement. We describe this “IS plug-in,” share challenges surrounding its creation and successful implementation across multiple courses, and explain its grounding in information literacy theory. We then provide insights and recommendations for future management education research that arose from experiences with the unique IS plug-in approach and in-depth application of new research in IL. We provide recommendations for expanding the IL Framework’s use and measurement, and improving our understanding of authority and information versus belief.


Insects ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 420
Author(s):  
Roma Durak ◽  
Malgorzata Jedryczka ◽  
Beata Czajka ◽  
Jan Dampc ◽  
Katarzyna Wielgusz ◽  
...  

The hemp aphid Phorodon cannabis Passerini is a well- known (Asia, Europe) or newly emerging (North America) insect. It is a monophagous insect pest causing considerable damage in field and glasshouse cultivations. The aim of this work was to study the effects of meteorological (temperature) and agronomical (herbicide) factors on the biology of the hemp aphid. In one experiment, hemp plants were kept at constant temperatures ranging from 20 to 30 °C, and aphid survival and fecundity were measured. In a related experiment conducted at 20 °C, plants were treated with field-appropriate rates of a selective graminicide containing quizalofop-P-tefuryl (40 gL−1, 4.38%, HRAC group 1), commonly used to control weeds in hemp, and aphid enzyme activity was measured in addition to population parameters. We found that hemp aphids could live, feed and reproduce within the whole studied range of temperatures, demonstrating its great evolutionary plasticity. However, the optimal temperature for development was 25 °C, at which the insect lived and reproduced for 25 and 15 days, respectively, with an average fecundity of 7.5 nymphs per reproduction day. The herbicide treatment increased the activity of superoxide dismutase (SOD), catalase (CAT), β-glucosidase, S-glutathione transferase (GST), oxidoreductive peroxidase (POD), and polyphenol oxidase (PPO) in the aphids, but only on certain days after treatment, which indicates a mild stress in aphid tissues, related to a higher reproduction and changed feeding behavior; aphids moved from the actively growing tips compared to untreated plants. The results of these experiments are discussed in terms of the impact on the future management of this pest.


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