scholarly journals Clinical and economic characteristics of emergency department visits due to acetaminophen toxicity in the USA

BMJ Open ◽  
2015 ◽  
Vol 5 (9) ◽  
pp. e007368 ◽  
Author(s):  
Ahmed Altyar ◽  
Lama Kordi ◽  
Grant Skrepnek
Author(s):  
Karen E Skinner ◽  
Amin Haiderali ◽  
Min Huang ◽  
Lee S Schwartzberg

Aim: Evaluation of monthly cost during metastatic triple-negative breast cancer (mTNBC) treatment. Patients & methods: Retrospective electronic medical record review of US females aged ≥18 years diagnosed with mTNBC between 1 January 2010 and 31 January 2016. Mean monthly costs per patient were evaluated from start of mTNBC treatment until transfer to hospice, end of record or 3 months prior to death. Results: The mean monthly cost of first line was $21,908 for 505 treated patients; 50.2% of cost was attributable to hospitalization and emergency department visits, and 32.7% to anticancer therapy. Similar patterns were observed for subsequent lines of therapy. Conclusion: The majority of costs were attributable to hospitalization and emergency department services, suggesting a need for effective interventions to reduce utilization of costly services.


2020 ◽  
Author(s):  
Lauren Alexis De Crescenzo ◽  
Barbara Alison Gabella ◽  
Jewell Johnson

Abstract Background. The transition in 2015 to the Tenth Revision of the International Classification of Disease, Clinical Modification (ICD-10-CM) in the USA led public health professionals to propose a surveillance definition of traumatic brain injury (TBI) that uses ICD-10-CM codes. The proposed definition excludes “unspecified injury of the head,” previously included in the ICD-9-CM TBI definition. The purpose of this study was to evaluate this change in surveillance methods on monthly rates of TBI-related emergency department visits in Colorado from 2012 to 2017.Results. The monthly rate of TBI-related emergency department visits in the transition month to ICD-10-CM (October 2015) decreased 41 visits per 100,000 population (p-value <0.0001), compared to September 2015, and remained low through December 2017, due to the exclusion of “unspecified injury of head” (ICD-10-CM code S09.90) in the proposed TBI definition. Conclusion. This study highlights a challenge in creating a standardized set of TBI ICD-10-CM codes for public health surveillance that provides comparable yet clinically relevant estimates over time. The findings inform estimation of TBI magnitude based on ICD coded data and decisions about allocating TBI resources based on an estimated TBI magnitude.


2018 ◽  
Vol Volume 10 ◽  
pp. 159-163 ◽  
Author(s):  
Jonathan D Shenkin ◽  
John Warren ◽  
Charles Spanbauer ◽  
Elaye Okunseri ◽  
Aniko Szabo ◽  
...  

2019 ◽  
Vol 127 (2) ◽  
pp. 279-286
Author(s):  
Phil Skolnick ◽  
Roger Crystal

AbstractThe legalization of cannabis for both recreational and medical use in the USA has resulted in a dramatic increase in the number of emergency department visits and hospital admissions for acute cannabinoid overdose (also referred to as cannabis intoxication and cannabis poisoning). Both “edibles” (often sold as brownies, cookies, and candies) containing large amounts of Δ9-tetrahydrocannabinol and synthetic cannabinoids (many possessing higher potencies and efficacies than Δ9-tetrahydrocannabinol) are responsible for a disproportionate number of emergency department visits relative to smoked cannabis. Symptoms of acute cannabinoid overdose range from extreme lethargy, ataxia, and generalized psychomotor impairment to feelings of panic and anxiety, agitation, hallucinations, and psychosis. Treatment of acute cannabinoid overdose is currently supportive and symptom driven. Converging lines of evidence indicating many of the symptoms which can precipitate an emergency department visit are mediated through activation of cannabinoid1 receptors. Here, we review the evidence that cannabinoid1 receptor antagonists, originally developed for indications ranging from obesity to smoking cessation and schizophrenia, provide a molecular approach to treating acute cannabinoid overdose.


Author(s):  
Behnam Nabavizadeh ◽  
Nizar Hakam ◽  
Jordan T. Holler ◽  
Nikan K. Namiri ◽  
Michael J. Sadighian ◽  
...  

Author(s):  
Omar Abdel-Rahman

Aim: To assess patterns of emergency department visits and subsequent hospitalization in relation to gender and socioeconomic status among a cohort of cancer survivors in the USA. Materials & methods: National Health Interview Survey datasets (2011–2017) were reviewed and participants with a history of cancer and complete information about emergency department visits in the past 12 months were included. Multivariable logistic regression analyses were used to assess factors associated with emergency department visits and subsequent hospitalization after the most recent emergency department visit. Results: A total of 22,240 cancer survivors were included in the current analysis; of which 16,133 participants (72.5%) who have not visited an emergency department in the past 12 months and 6107 participants (27.5%) who have visited an emergency department in the past 12 months. Multivariable logistic regression analysis suggested the following factors are associated with emergency department visits; younger age (odds ratio [OR] with increasing age: 0.98; 95% CI: 0.98–0.99), female gender (OR: 1.07; 95% CI: 1.00–1.15), African American race (OR: 1.26; 95% CI: 1.13–1.40), unmarried status (OR for married vs unmarried: 0.79; 95% CI: 0.74–0.84), lower yearly earnings (OR: 1.36; 95% CI: 1.20–1.54), poor health status (OR: 7.02; 95% CI: 6.02–8.18) and incomplete health insurance coverage (OR for complete coverage vs incomplete coverage: 0.66; 95% CI: 0.54–0.80). On the other hand, the following factors were associated with subsequent hospitalization: older age (OR: 1.004; 95% CI: 1.000–1.008), male gender (OR for female vs male: 0.86; 95% CI: 0.78–0.94), unmarried status (OR for married vs unmarried status: 0.80; 95% CI: 0.73–0.88), not working (OR: 1.44; 95% CI: 1.23–1.68), lower yearly earnings (OR: 1.31; 95% CI: 1.07–1.60), poor health status (OR: 8.43; 95% CI: 6.76–10.51) and lack of health insurance coverage (OR for complete coverage vs incomplete coverage: 0.71; 95% CI: 0.55–0.93). Conclusion: Female cancer survivors were more likely to visit the emergency department, whereas they were less likely to be subsequently hospitalized. Cancer survivors with lower socioeconomic status were more likely to visit emergency departments and to be subsequently hospitalized.


2015 ◽  
Vol 61 (2) ◽  
pp. 389-399 ◽  
Author(s):  
Mahesh Gajendran ◽  
Chandraprakash Umapathy ◽  
Priyadarshini Loganathan ◽  
Jana G. Hashash ◽  
Ioannis E. Koutroubakis ◽  
...  

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