scholarly journals Infant feeding, appetite and satiety regulation, and adiposity during infancy: a study design and protocol of the ‘MAS-Lactancia’ birth cohort

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e051400
Author(s):  
Ivonne Ramirez-Silva ◽  
Carolina Pérez Ferrer ◽  
Ana Carolina Ariza ◽  
Marcela Tamayo-Ortiz ◽  
Sofía Barragán ◽  
...  

IntroductionThe prevalence of childhood obesity has risen dramatically in recent years. A proportion of this burden has been attributed to factors that occur during the first 1000 days of life such as genetic predisposition, breast feeding and complementary feeding. Although the mechanisms by which these factors affect weight and adiposity are less well understood, appetite and satiety regulation may be a key to understanding them. This cohort study aims to investigate the role of appetite and satiety regulation as a mediator in the association between infant feeding practices and genetic polymorphisms with children’s growth, adiposity and metabolic risk factors.Methods and analysis‘MAS-Lactancia’ (the first word means ‘more’ and is also an acronym in Spanish for ‘Appetite and Satiety Mechanisms’, the second word is ‘breastfeeding’) is an open, ongoing, prospective birth cohort that began the enrolment in 2016 of mother–child pairs affiliated to the Mexican Social Security Institute and that live in the city of Cuernavaca, Mexico. Pregnant women between 16-week and 22-week gestation are followed during the second half of their pregnancies, at birth and throughout their infant’s first 48 months of life (at 1 month, 3 months, 6 months, 9 months, 12 months, 18 months, 24 months, 36 months and 48 months) at the clinic and at-home visits that include questionnaires, anthropometric measurements and biospecimen collection. The main exposure variables are infant feeding (breast feeding and complementary feeding) and genetic polymorphisms (fat mass and obesity-associated, leptin and adiponectin genes). Outcome variables include infant’s growth, adiposity and metabolic risk factors. We will conduct longitudinal models and path analyses to identify the potential mediating role of satiety and appetite indicators (leptin, adiponectin, insulin concentrations, appetite and satiety perception).Ethics and disseminationThe study protocol, data collection instruments, consent forms and procedures were approved by the institutional review boards of the National Institute of Public Health and the Mexican Social Security Institute in Mexico. Findings will be disseminated through conferences, peer-reviewed publications and meetings with stakeholders.

2015 ◽  
Vol 18 (15) ◽  
pp. 2864-2873 ◽  
Author(s):  
Sinéad M O’Donovan ◽  
Deirdre M Murray ◽  
Jonathan O’B Hourihane ◽  
Louise C Kenny ◽  
Alan D Irvine ◽  
...  

AbstractObjectiveTo describe adherence with infant feeding and complementary feeding guidelines.DesignProspective study of infant feeding and complementary feeding practices were collected as part of the Cork BASELINE Birth Cohort Study.SettingCork, Ireland.SubjectsData are described for the 823 infants for whom a diary was completed.ResultsBreast-feeding was initiated in 81 % of infants, and 34 %, 14 % and 1 % of infants were exclusively breast-fed at hospital discharge, 2 and 6 months, respectively. Stage one infant formula decreased from 71 % at 2 months to 13 % at 12 months. The majority of infants (79 %) were introduced to solids between 17 and 26 weeks and 18 % were given solid foods before 17 weeks. Mothers of infants who commenced complementary feeding prior to 17 weeks were younger (29·8 v. 31·5 years; P<0·001) and more likely to smoke (18 v. 8 %; P=0·004). The first food was usually baby rice (69 %), infant breakfast cereals (14 %) or fruit/vegetables (14 %). Meals were generally home-made (49 %), cereal-based (35 %), manufactured (10 %), dairy (3 %) and dessert-based (3 %). The median gap between the first–second, second–third, third–fourth and fourth–fifth new foods was 4, 2, 2 and 2 d, respectively.ConclusionsWe present the largest prospective cohort study to date on early infant feeding in Ireland. The rate of breast-feeding is low by international norms. Most mothers introduce complementary foods between 4 and 6 months with lengthy gaps between each new food/food product. There is a high prevalence of exposure to infant breakfast cereals, which are composite foods, among the first foods introduced.


2005 ◽  
Vol 40 (7) ◽  
pp. 599-604 ◽  
Author(s):  
M. Barbieri ◽  
M.R. Rizzo ◽  
M. Papa ◽  
R. Acampora ◽  
L. De Angelis ◽  
...  

2016 ◽  
Vol 68 (16) ◽  
pp. C85
Author(s):  
Seung Hwan Han ◽  
Pyung Chun Oh ◽  
Min Soo Kim ◽  
Yae Min Park ◽  
Kwang Kon Koh ◽  
...  

2018 ◽  
Vol 89 (3) ◽  
pp. 331-340 ◽  
Author(s):  
Esra Sinem Kemer Doğan ◽  
Fatma Yeşim Kırzıoğlu ◽  
Burak Doğan ◽  
Özlem Fentoğlu ◽  
Banu Kale ◽  
...  

2014 ◽  
Vol 37 (3) ◽  
pp. 138-141 ◽  
Author(s):  
Tamanna Begum ◽  
SK Azimul Hoque ◽  
Md Rafiqul Islam ◽  
Soofia Katoon ◽  
Azanta Rani Shah

Background: Appropriate breastfeeding and complementary feeding practices are the fundamental to children’s nutrition, health and survival during the first year of life. WHO and UNICEF have articulated a global strategy for poor infant feeding practices directly and indirectly contributes to under nutrition, morbidity and mortality in infant. Objective: This study was designed to determine the breast feeding (BF) and complementary feeding (CF) practices in study population. Methodology: This descriptive cross sectional study was carried out in Pediatrics out patients department (OPD) of Shahid Surhawardy Medical College and Hospital, from January 2009 to December 2009. Feeding history of total 250 babies age >6 months to <1 year was taken from mothers. Results: Among 250 total babies, prelacteal feed was given in 29.2%(73/250), colostrum was given in 79.2%(198/250) and exclusive breast feeding upto six months was given in 24%(60/250) babies. CF was started in 242 babies and it was too early before six months in 29.6%(74/250) cases. Amount of CF was adequate in 66.9%(162/ 242) and composition of CF was good enough in 58.3%(141/242) babies. Conclusion: In this study CF was introduced before 6 months in one third babies and amount was inadequate in same numbers of children. There is need for promotion and protection of optimal infant feeding practices for improving nutritional status of our children. DOI: http://dx.doi.org/10.3329/bjch.v37i3.18616 Bangladesh J Child Health 2013; Vol.37(3): 138-141


PLoS ONE ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. e0211557 ◽  
Author(s):  
Bette Loef ◽  
Debbie van Baarle ◽  
Allard J. van der Beek ◽  
Piet K. Beekhof ◽  
Linda W. van Kerkhof ◽  
...  

2009 ◽  
Vol 13 (4) ◽  
pp. 504-513 ◽  
Author(s):  
Maijaliisa Erkkola ◽  
Maija Salmenhaara ◽  
Carina Kronberg-Kippilä ◽  
Suvi Ahonen ◽  
Tuula Arkkola ◽  
...  

AbstractObjectiveTo assess milk feeding on the maternity ward and during infancy, and their relationship to sociodemographic determinants. The validity of our 3-month questionnaire in measuring hospital feeding was assessed.DesignA prospective Finnish birth cohort with increased risk to type 1 diabetes recruited between 1996 and 2004. The families completed a follow-up form on the age at introduction of new foods and age-specific dietary questionnaires.SettingType 1 Diabetes Prediction and Prevention (DIPP) project, Finland.SubjectsA cohort of 5993 children (77 % of those invited) participated in the main study, and 117 randomly selected infants in the validation study.ResultsBreast milk was the predominant milk on the maternity ward given to 99 % of the infants. Altogether, 80 % of the women recalled their child being fed supplementary milk (donated breast milk or infant formula) on the maternity ward. The median duration of exclusive breast-feeding was 1·4 months (range 0–8) and that of total breast-feeding 7·0 months (0–25). Additional milk feeding on the maternity ward, short parental education, maternal smoking during pregnancy, small gestational age and having no siblings were associated with a risk of short duration of both exclusive and total breast-feeding. In the validation study, 78 % of the milk types given on the maternity ward fell into the same category, according to the questionnaire and hospital records.ConclusionsThe recommendations for infant feeding were not achieved. Infant feeding is strongly influenced by sociodemographic determinants and feeding practices on the maternity wards. Long-term breast-feeding may be supported by active promotion on the maternity ward.


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