scholarly journals Platelet-rich plasma injection for tennis elbow: did it ever work?

2022 ◽  
Vol 8 (1) ◽  
pp. e001258
Author(s):  
Teemu Karjalainen ◽  
Bethan Richards ◽  
Rachelle Buchbinder
Keyword(s):  
Clinical Trials ◽  
Preparation Method ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Cochrane Review ◽  
Clinical Use ◽  
Approval Process ◽  
Plasma Injection ◽  
Phases Of Development ◽  
Better Than

Platelet-rich plasma (PRP) is a commonly used treatment for tendinopathies such as tennis elbow despite the questionable evidence of its efficacy. A recent Cochrane review suggests that it likely does not provide clinically meaningful benefits in people with tennis elbow. In this viewpoint, we discuss how lack of regulation allowed aggressive marketing and clinical use without normal phases of drug development and approval process or rigorous evidence of benefits. Since several phases of development were bypassed, we still do not know the optimal preparation method and dosing of PRP for tendinopathies. Furthermore, several clinical trials compared PRP with other interventions although it was unclear if PRP was better than placebo and these comparisons created distraction rather than improved understanding of its effects.

scholarly journals Effects of intralesional platelet-rich plasma in the patients with lateral epicondylitis of elbow

2019 ◽  
Vol 12 (3) ◽  
pp. 138-141
Author(s):  
Mohammad Tariqul Islam ◽  
M. A. Shakoor ◽  
Afsana Mahjabin ◽  
Md. Ali Emran
Keyword(s):  
Visual Analogue Scale ◽  
Daily Living ◽  
Analogue Scale ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Lateral Epicondylitis ◽  
Activity Of Daily Living ◽  
Evaluation Tool ◽  
Plasma Injection ◽  
The Difference

Lateral epicondylitis (tennis elbow) is a major cause of musculoskeletal pain involving common extensor origin of the forearm. This study was done to determine the effects of platelet-rich plasma on 15 patients with lateral epicondylitis. Selected patients were given intralesional platelet-rich plasma injection, activity of daily living instructions and paracetamol. Patients were assessed every 14 days interval by visual analogue scale, and the patient rated tennis elbow evaluation. Treatment response according to visual analogue scale and patient rated tennis elbow evaluation tool, the difference of improvement was found in respect to time, from pretreatment W1 (just before 1st Intervention) score to W11 score in every alternate week (p<0.005). This indicates that intralesional platelet-rich plasma is effective in the patients with lateral epicondylitis of elbow.

Results of Platelet Rich Plasma Injection in Chronic Lateral Humeral Epicondylar Tendinopathy

2021 ◽  
Vol 15 (11) ◽  
pp. 3481-3483
Author(s):  
Subhan Shahid ◽  
Muhammad Abubakar ◽  
Rehan Abdul Sattar ◽  
Muhammad Hasan
Keyword(s):  
Pain Relief ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Tertiary Care ◽  
Functional Improvement ◽  
Care Hospital ◽  
Effective Treatment Option ◽  
Plasma Injection ◽  
The Mean ◽  
Extensor Carpi Radialis

Background: Lateral humeral epicondylitis or tennis elbow is one of the commonest causes of pain around elbow. Platelet rich plasma is a stimulant for repair in various tendinopathies. Previous studies have suggested platelet rich plasma as a safe & effective treatment option in tennis elbow. Objective: To evaluate the clinical efficacy in terms of relief of pain& functional improvement after PRP injection in patients with chronic tennis elbow. Materials & Method: The trial was conducted in a tertiary care hospital in 70 patients over a period of 2 years.3ml of PRP was injected in & around the Extensor Carpi Radialis Brevis. Pain relief & functional improvement were assessed using visual analogue scale q-DASH scale at 1 month, 3 months, 6 months & 1 year. Results: The mean Nirshl pain score & q-DASH started improving after 02 weeks but significant improvement was seen after 3 months & pain decreased continuously for up to 1 year (p<0.0001). Conclusion: PRP offers a significant pain relief & functional improvement from 3 months to 1 year after injection. Keywords: Lateral epicondylar tendinopathy, platelet rich plasma

Functional outcome of autologous platelet rich plasma injection in plantar fasciitis and tennis elbow

2022 ◽  
Vol 7 (2) ◽  
pp. 76-81
Author(s):  
Rameshwar Sharan Gupta ◽  
Manish Khanna
Keyword(s):  
Repeated Measures ◽  
Plantar Fasciitis ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Biological Response ◽  
Osteoblastic Differentiation ◽  
Plasma Injection ◽  
Significant Difference ◽  
Autologous Platelet Rich Plasma ◽  
Autologous Platelet

Recent developments in cellular and molecular biology have emerged as a potent tool in the management of orthopaedic illnesses and injuries. Upon binding to the target cell receptor, the growth factor from platelets triggers the activation of an intracellular signal transduction system, which results in a biological response that is essential for chemotaxis, cell proliferation, and osteoblastic differentiation. The aim of this study is to determine the efficacy and safety of autologous platelet-rich plasma injection in tennis elbow and plantar fasciitis. We conducted a prospective study with patients who were suffering from plantar fasciitis (n=37) or tennis elbow (n=23) and were given with autologous platelet-rich plasma injection. A short term follow up of all these cases were done at regular intervals for 1, 4, 8, and 12 weeks. The clinical outcomes were analyzed with severity of pain and movements of the pathological part. The functional outcomes were analyzed with VAS and AOFAS scoring for plantar fasciitis and VAS and Mayo’s elbow scoring for tennis elbow. All these patients were statistically analyzed by repeated measures ANOVA test. Our investigation found a statistically significant difference between pre-procedural and post-procedural scores in both the subjective (VAS) and functional (AOFAS and Mayo elbow score) grading systems used in this study. Patients who received an autologous platelet-rich plasma injection experienced a statistically significant (p &#60;0.05) improvement in their ability to combat both of the musculoskeletal illnesses studied. Autologous platelet-rich plasma acts as a promising efficacious biological therapeutic agent for use in musculoskeletal disorders such as plantar fasciitis and tennis elbow without major complications upon its usage.

PLATELET-RICH PLASMA INJECTION IN EARLY OSTEOARTHRITIS KNEE FOLLOW-UP 1 YEAR

2021 ◽  
pp. 6-8
Author(s):  
Abdul Hassan Khan ◽  
Prasanta Kumar Pujari ◽  
Bikramjit Gayen ◽  
Dipak Kumar Jha ◽  
Debarshi Jana
Keyword(s):  
Conservative Treatment ◽  
Platelet Rich Plasma ◽  
Treatment Options ◽  
Repair Process ◽  
Plasma Injection ◽  
Osteoarthritis Knee ◽  
The One ◽  
Tissue Recovery ◽  
Natural Healing ◽  
Better Than

Background: Osteoarthritis (OA) knee is one of the most prevalent musculoskeletal disorders in elderly population. It has got various treatment options but most are unsatisfactory. In recent years Platelet-rich plasma (PRP) is emerged as a promising treatment modality and classied as “Orthobiologics”. PRPenhances tissue recovery, by catalysing the body's natural healing response and tissue repair process. Aim And Objectives:Tocompare the efcacies oftreatmentwithPRPinjectionandconservative treatmentwithNSAIDSandexercise inOAknee. Materials And Methods:This was a observational study in which comparisons of different outcomes were made on the efcacies of the treatments with PRPinjection and compared to conservative treatment with NSAIDS and exercise in OAknee. The study was conducted in the Department of Orthopedics in Ramkrishna Mission SevaPratisthan. Atotal number of 60 patients with power 80% were randomly selected from the patients with OA attended OPD during the period from June 2019 to June 2021. The patients were divided into two groups of 30 patients in each group. The patients of the one group were treated with intra-articular PRPinjection and the patients of another group were treated conservatively with NSAIDS and exercise. After the completion of treatment, the patients were followed-up for 1 year and the outcomes of the treatments were assessed by WOMAC (The Western Ontario and McMaster Universities Osteoarthritis Index) knee assessment scoring system. Results:At 1 year the completion of treatments it was found that both clinical and functional improvements of the patients were signicantly better than the initiation of treatments (p<0.0001). However, the improvements of the patients treated with PRPinjection were signicantly better than the patients treated conservatively with NSAIDS and exercise (p<0.001). Conclusion: From the results of the study it may be concluded that PRP injection is better than conservative treatment with NSAIDS and exercise to treat OAknee

scholarly journals Management of tennis elbow: a survey of UK clinical practice

2017 ◽  
Vol 11 (3) ◽  
pp. 233-238 ◽  
Author(s):  
Marcus Bateman ◽  
Andrew G. Titchener ◽  
David I. Clark ◽  
Amol A. Tambe
Keyword(s):  
Online Survey ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Second Line ◽  
Cross Sectional ◽  
Shockwave Therapy ◽  
Plasma Injection ◽  
Wide Variability ◽  
The Uk ◽  
Corticosteroid Injections

Background Tennis elbow is a common condition in the UK but there are no guidelines on how best to manage the condition. The purpose of the present study was to establish the current UK practice in managing patients with chronic tennis elbow. Methods A cross-sectional online survey of UK surgeons and therapists was conducted in June 2017. Results In total, 275 responses were received, the majority from consultant surgeons and experienced physiotherapists. In total, 81% recommended exercise-based physiotherapy as the first-line intervention. Second-line treatments varied widely, with corticosteroid injections being the most popular (27%), followed by shockwave therapy, platelet-rich plasma injection, surgery, acupuncture and a wait-and-see policy. Conclusions There is wide variability of treatments offered when physiotherapy fails patients with tennis elbow. The majority of second-line interventions lack evidence to support their use and, in the case of corticosteroid injections, may even be harmful in the long term. There is a clear need for national guidance based on best evidence to aid clinicians in their treatment approach.

Sign in / Sign up

Export Citation Format

Share Document