Adverse psychosocial work factors, blood pressure and hypertension incidence: repeated exposure in a 5-year prospective cohort study

Introduction: Few data exist describing the temporal association between the time spent within various intensities of physical activity (PA) and cardiometabolic health outcomes in youth. Study Hypotheses: In contrast to light- or moderate-intensity physical activity (PA) Vigorous- intensity PA would be associated with a reduced risk incident overweight and high normal blood pressure and (2) time spent in vigorous-intensity but not moderate- or light-intensity PA would be associated with cardiometabolic risk factors two years following baseline measurements. Design and Methods: This was a 3-year prospective cohort study of objectively-measured PA (Actical) in 315 youth aged 9 to-17 yrs of age studied in 14 schools. The primary exposure variable was PA intensity. The main outcomes measures were incident overweght status and high normal blood pressure. Secondary outcomes included disproportionate weight gain (annual change in body mass index Z score), waist circumference, systolic blood pressure (SBP), and cardiorespiratory fitness (VO 2 max) at the three year time point. Results: After three year follow-up, increasing time spent in any of the three PA intensities was not associated with incident overweight or incident high normal blood pressure. Compared to the lowest quartile, waist circumference [β = -0.04 95% CI = -0.07 to -0.01; p trend <0.01) and SBP [β = -3.08 95% CI = -6.79 to 0.64; p trend = 0.05] were lower in boys while VO 2 max was significantly higher [43.3 (39.6-46.4) vs 50.2 (43.8-52.9) mL/kg/min; p trend <0.01] in both boys and girls in the highest quartile of vigorous PA. These trends were not observed or reversed across quartiles of moderate- and light-intensity PA. Conclusions: Increasing time spent in vigorous-intensity PA at 12 years of age was associated with a more favorable cardiometabolic profile two years later. Similar trends were not evident for lower intensity PA. Experimental trials are needed to determine if these associations are causal in nature.

Download Full-text

Abstract 006: Blood Pressure Categories and Newly Progression of Carotid Artery Plaques in a Prospective Cohort Study: The Suita Study

Hypertension ◽

10.1161/hyp.74.suppl_1.006 ◽

2019 ◽

Vol 74 (Suppl_1) ◽

Author(s):

Yoshihiro Kokubo ◽

Makoto Watanabe ◽

Aya Higashiyama ◽

Yoshihiro Miyamoto

Keyword(s):

Blood Pressure ◽

Cohort Study ◽

Carotid Artery ◽

Prospective Cohort Study ◽

Prospective Cohort

Download Full-text

Bidirectional association between blood pressure and depressive symptoms in young and middle-age adults: A cohort study

Epidemiology and Psychiatric Sciences ◽

10.1017/s2045796020000542 ◽

2020 ◽

Vol 29 ◽

Author(s):

Sang Won Jeon ◽

Yoosoo Chang ◽

Se-Won Lim ◽

Juhee Cho ◽

Han-Na Kim ◽

...

Keyword(s):

Blood Pressure ◽

Cohort Study ◽

Depressive Symptoms ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Heart Association ◽

Epidemiologic Studies ◽

Incident Hypertension ◽

Bidirectional Association

Abstract Aims To evaluate the bidirectional relationship between blood pressure (BP) and depressive symptoms using a large prospective cohort study. Methods Prospective cohort study was performed in 276 244 adults who participated in a regular health check-up and were followed annually or biennially for up to 5.9 years. BP levels were categorised according to the 2017 American College of Cardiology and American Heart Association hypertension guidelines. Depressive symptoms were assessed using Centre for Epidemiologic Studies-Depression (CESD) questionnaire and a cut-off score of ≥25 was regarded as case-level depressive symptoms. Results During 672 603.3 person-years of follow-up, 5222 participants developed case-level depressive symptoms. The multivariable-adjusted hazard ratios (HRs) [95% confidence interval (CI)] for incident case-level depressive symptoms comparing hypotension, elevated BP, hypertension stage 1 and hypertension stage 2 to normal BP were 1.07 (0.99–1.16), 0.93 (0.82–1.05), 0.89 (0.81–0.97) and 0.81 (0.62–1.06), respectively (p for trend <0.001). During 583 615.3 person-years of follow-up, 27 787 participants developed hypertension. The multivariable-adjusted HRs (95% CI) for incident hypertension comparing CESD 16–24 and ⩾25 to CESD < 16 were 1.05 (1.01–1.11) and 1.12 (1.03–1.20), respectively (p for trend <0.001) and in the time-dependent models, corresponding HRs (95% CI) were 1.12 (1.02–1.24) and 1.29 (1.10–1.50), respectively (p for trend <0.001). Conclusions In this large cohort study of young and middle-aged individuals, higher BP levels were independently associated with a decreased risk for developing case-level depressive symptoms and depressive symptoms were also associated with incident hypertension. Further studies are required to elucidate the mechanisms underlying the bidirectional association between BP levels and incident depression.

Download Full-text