scholarly journals 23: VASCULAR INFLAMMATION AND AORTIC WALL CHARACTERISTICS MODULATE FOLLOWING LIFESTYLE CHANGES IN PSORIASIS PATIENTS AT 1 YEAR FOLLOW UP

2016 ◽  
Vol 64 (3) ◽  
pp. 816.2-816
Author(s):  
A Joshi ◽  
P Shukla ◽  
TM Aberra ◽  
JB Lerman ◽  
B Natarajan ◽  
...  
Keyword(s):  
Wall Thickness ◽  
Phase Contrast ◽  
Aortic Wall ◽  
Vascular Inflammation ◽  
Surrogate Marker ◽  
Lifestyle Changes ◽  
Phase Contrast Mri ◽  
Exercise Frequency ◽  
Mri Scans

Purpose of StudyPsoriasis (PSO), a chronic inflammatory skin disease, is associated with increased CV risk and vascular inflammation (VI). However, the effect of therapeutic lifestyle changes (TLC) including exercise on VI over time is unknown. We hypothesized that TLC would lead to an improvement in VI at 1 year accompanied by improvements in aortic wall characteristics.Methods Used65 PSO patients, recruited consecutively, underwent FDG PET/CT, phase contrast MRI scans and clinical visits for evaluation of VI, wall characteristics and exercise frequency, at baseline and 1 year follow-up. VI was measured as Target-to-background ratio (TBR), and aortic distensibility (AD) and wall thickness were assessed by commercial software on phase contrast MRI scans. Clinical parameters were ascertained by both survey and provider.Summary of ResultsVI decreased at 1 year (6.5% decrease in TBR; p<0.0001), and was inversely associated with exercise frequency beyond adjustment for CV risk factors (β=−0.27; p=0.001). Furthermore, this decrease in VI was associated with improvement in AD (40% increase; p<0.001) and aortic wall thickness (8.5% decrease; p<0.001).ConclusionsOur findings suggest that VI improves with TLC. This 6.5% decrease in VI could lead to ∼30% reduction in future adverse events, based on a recent large prospective study. This VI reduction is also associated with improved aortic wall characteristics suggesting that targeting VI as a surrogate marker holds promise to understand the effects of TLC on CV disease.Abstract 23 Figure 1

scholarly journals Evolution of aortic wall thickness: long-term follow up from the Multi-Ethnic Study of Atherosclerosis (MESA)

2013 ◽  
Vol 15 (S1) ◽  
Author(s):  
Chia-Ying Liu ◽  
Doris Chen ◽  
Gisela Teixido-Tura ◽  
Colin O Wu ◽  
Atul R Chugh ◽  
...  
Keyword(s):  
Wall Thickness ◽  
Aortic Wall ◽  
Ethnic Study ◽  
Long Term Follow Up ◽  
Aortic Wall Thickness

scholarly journals Phase-contrast MRI-based elastography technique detects early hypertensive changes in ex vivo porcine aortic wall

2009 ◽  
Vol 29 (3) ◽  
pp. 583-587 ◽  
Author(s):  
David A. Woodrum ◽  
Joerg Herrmann ◽  
Amir Lerman ◽  
Anthony J. Romano ◽  
Lilach O. Lerman ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Aortic Wall ◽  
Ex Vivo ◽  
Phase Contrast Mri

Prediction of Progression or Regression of Type A Aortic Intramural Hematoma by Computed Tomography

Circulation ◽  
1999 ◽  
Vol 100 (suppl_2) ◽  
Author(s):  
Shuichiro Kaji ◽  
Kazuhiro Nishigami ◽  
Takashi Akasaka ◽  
Takeshi Hozumi ◽  
Tsutomu Takagi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Wall Thickness ◽  
Aortic Wall ◽  
Intramural Hematoma ◽  
Type A ◽  
Ct Images ◽  
Aortic Diameter ◽  
Aortic Wall Thickness ◽  
Aortic Intramural Hematoma

Background —It has been reported that early surgery should be required for patients with type A aortic intramural hematoma (IMH) because it tends to develop classic aortic dissection or rupture. However, the anatomic features of type A IMH that develops dissection or rupture are unknown. The purpose of this study was to investigate the predictors of progression or regression of type A IMH by computed tomography (CT). Methods and Results —Twenty-two consecutive patients with type A IMH were studied by serial CT images. Aortic diameter and aortic wall thickness of the ascending aorta were estimated in CT images at 3 levels on admission and at follow-up (mean 37 days). We defined patients who showed increased maximum aortic wall thickness in the follow-up CT (n=9) or died of rupture (n=1) as the progression group (n=10). The other 12 patients, who all showed decreased maximum wall thickness, were categorized as the regression group. In the progression group, the maximum aortic diameter in the initial CT was significantly greater than that in the regression group (55±6 vs 47±3 mm, P =0.001). A Cox regression analysis revealed that the maximum aortic diameter was the strongest predictor for progression of type A IMH. We considered the optimal cutoff value to be 50 mm for the maximum aortic diameter to predict progression (positive predictive value 83%, negative predictive value 100%). Conclusions —Maximum aortic diameter estimated by the initial CT images is predictive for progression of type A IMH.

A phase-contrast MRI study of physiologic cerebral venous flow

2009 ◽  
Author(s):  
Souraya Stoquart-ElSankari ◽  
Pierre Lehmann ◽  
Agnès Villette ◽  
Marek Czosnyka ◽  
Marc-Etienne Meyer ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Phase Contrast Mri ◽  
Venous Flow ◽  
Mri Study

Assessment of Myocardial Viability in Persistent Defects on Thallium-201 SPECT after Reinjection Using Gradient-Echo MRI

1996 ◽  
Vol 35 (05) ◽  
pp. 146-152 ◽  
Author(s):  
A. Kögler ◽  
H.-A. Schmitt ◽  
D. Emrich ◽  
H. Kreuzer ◽  
D. L. Munz ◽  
...  
Keyword(s):  
Wall Thickness ◽  
Myocardial Viability ◽  
Cardiac Cycle ◽  
Single Photon ◽  
Contractile Function ◽  
Left Ventricular ◽  
Wall Thickening ◽  
Gradient Echo ◽  
Systolic Wall Thickening

SummaryThis prospective study assessed myocardial viability in 30 patients with coronary heart disease and persistent defects despite reinjection on TI-201 single-photon computed tomography (SPECT). In each patient, three observers graded TI-201 uptake in 7 left ventricular wall segments. Gradient-echo magnetic resonance imaging in the region of the persistent defect generated 12 to 16 short axis views representing a cardiac cycle. A total of 120 segments were analyzed. Mean end-diastolic wall thickness and systolic wall thickening (± SD) was 11.5 ± 2.7 mm and 5.8 ± 3.9 mm in 48 segments with normal TI-201 uptake, 10.1 ± 3.4 mm and 3.7 ± 3.1 mm in 31 with reversible lesions, 11.3 ± 2.8 mm and 3.3 ± 1.9 mm in 10 with mild persistent defects, 9.2 ± 2.9 mm and 3.2 ±2.2 mm in 15 with moderate persistent defects, 5.8 ± 1.7 mm and 1.3 ± 1.4 mm in 16 with severe persistent defects, respectively. Significant differences in mean end-diastolic wall thickness (p <0.0005) and systolic wall thickening (p <0.005) were found only between segments with severe persistent defects and all other groups, but not among the other groups. On follow-up in 11 patients after revascularization, 6 segments with mild-to-moderate persistent defects showed improvement in mean systolic wall thickening that was not seen in 6 other segments with severe persistent defects. These data indicate that most myocardial segments with mild and moderate persistent TI-201 defects after reinjection still contain viable tissue. Segments with severe persistent defects, however, represent predominantly nonviable myocardium without contractile function.

Anterior Mediastinal Paraganglioma Mimicking Thymoma

2012 ◽  
Vol 15 (3) ◽  
pp. 170
Author(s):  
Hee Moon Lee ◽  
Dong Seop Jeong ◽  
Pyo Won Park ◽  
Wook Sung Kim ◽  
Kiick Sung ◽  
...  
Keyword(s):  
Mediastinal Mass ◽  
Aortic Wall ◽  
Anterior Wall ◽  
Ascending Aorta ◽  
Anterior Mediastinal Mass ◽  
Arterial Reconstruction ◽  
Ct Evaluation ◽  
One Year ◽  
Mediastinal Paraganglioma

A 54-year-old man was referred to our institution with hemoptysis and hoarseness of 1 year's duration. A computed tomography (CT) scan showed an anterior mediastinal mass (2.5 cm x 1.0 cm), which was diagnosed as thymoma. The tumor was resected under a sternotomy. The tumor had invaded the anterior wall of the ascending aorta. With the patient under cardiopulmonary bypass, the aortic wall invaded by the mass was resected, and arterial reconstruction was performed with patch material. The tumor was revealed to be a tumor of neuronal origin. The patient's postoperative course was uneventful. The patient was discharged on postoperative day 9. One year after the operation, a follow-up chest CT evaluation showed no specific complications or recurrence.

Gadolinium Effect on 4D Phase Contrast MRI

2019 ◽  
Vol 29 (2) ◽  
pp. 27-32
Author(s):  
Yu-Mi Jang ◽  
◽  
Kyoung-Jin Park ◽  
Seon-Wook Yang ◽  
Dae-Keon Seo
Keyword(s):  
Phase Contrast ◽  
Phase Contrast Mri

Paranasal Sinus Mucocele Clinical, imagistic and biochemical aspects

2018 ◽  
Vol 69 (8) ◽  
Author(s):  
Doina Vesa ◽  
Cristian Martu ◽  
Razvan Leata ◽  
Ludmila Lozneanu ◽  
luminita Radulescu ◽  
...  
Keyword(s):  
Facial Asymmetry ◽  
Retrospective Case ◽  
Mri Scans ◽  
The One ◽  
Ethmoid Sinuses ◽  
Retrospective Case Study ◽  
Cellular Components ◽  
Ct And Mri

Paranasal mucoceles are a type of cysts that evolve slowly and are asymptomatic; this poses a difficulty in diagnosing the patient because the symptoms can go unnoticed. The mucocele evolves unpredictably. On the one hand, it can become infected turning into pyoceles and on the other hand, it can invade important regions such as the orbital, cranial or genian regions, creating facial asymmetry. This is a retrospective case study of 37 patients diagnosed with sinus mucoceles, followed up by clinical examination and paraclinical tests such as CT and MRI scans. The biochemical components of the liquid from within the mucocele were analyzed and the following criteria were recorded: NaCl-, Cl-, Na+ and cholesterine as well as cellular components such as mastocytes, macrophages, hematocytes and leucocytes. In all cases, the treatment option was surgery with favorable post-operative and follow-up evaluation. The mucoceles that appeared post-operatively (maxillary and ethmoid sinuses) evolved more rapidly than the mucoceles that were induced byan external injury. Longer follow-up of operated patients permitted a more timely diagnosis of recurrences.

AB0967 Determinants of Aortic Wall Thickness in Patients without Aortitis: A Computed Tomography-Based Study: Table 1

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 1119.3-1120
Author(s):  
A. Nakhleh ◽  
D. Rimar ◽  
I. Rukhkyan ◽  
V. Wolfson ◽  
I. Rosner ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Wall Thickness ◽  
Aortic Wall ◽  
Aortic Wall Thickness
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