Syncope in pulmonary embolism: a retrospective cohort study

2020 ◽  
pp. postgradmedj-2020-138677
Author(s):  
Craig Richmond ◽  
Hannah Jolly ◽  
Chris Isles
Keyword(s):  
Pulmonary Embolism ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
District General Hospital ◽  
Clinical Feature ◽  
Pulmonary Angiogram ◽  
Ct Pulmonary Angiogram ◽  
Age Range ◽  
Symptoms And Signs

ObjectiveTo determine the prevalence of syncope or collapse in pulmonary embolism (PE).MethodsA retrospective cohort study was conducted. We examined the frequency with which syncope or collapse (presyncope) occurred alone or with other symptoms and signs in an unselected series of 224 patients presenting to a district general hospital with PE between September 2012 and March 2016. Confirmation of PE was by CT pulmonary angiogram in each case.ResultsOur cohort of 224 patients comprised 97 men and 127 women, average age 66 years with age range of 21–94 years. Syncope or collapse was one of several symptoms and signs that led to a diagnosis of PE in 22 patients (9.8%) but was never the sole presenting feature. In descending order, these other clinical features were hypoxaemia (17 patients), dyspnoea (12), chest pain (9), tachycardia (7) and tachypnoea (7). ECG abnormalities reported to occur more commonly in PE were found in 13/17 patients for whom ECGs were available. Patients with PE presenting with syncope or collapse were judged to have a large clot load in 15/22 (68%) cases.ConclusionSyncope was a frequent presenting symptom in our study of 224 consecutive patients with PE but was never the sole clinical feature. It would be difficult to justify routine testing for PE in patients presenting only with syncope or collapse.

scholarly journals Impact of COVID ‐19 on glycaemic control: a retrospective cohort study in a local district general hospital

2020 ◽  
Vol 37 (5) ◽  
pp. 164-167
Author(s):  
Aaisha Saqib ◽  
Pratik Solanki ◽  
Matthew Carroll ◽  
Andrew Gough ◽  
Victor Oguntolu
Keyword(s):  
Cohort Study ◽  
Glycaemic Control ◽  
General Hospital ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
District General Hospital ◽  
Local District

Mortality at 30 and 90 days in elderly patients with pulmonary embolism: a retrospective cohort study

2014 ◽  
Vol 10 (4) ◽  
pp. 431-436 ◽  
Author(s):  
Hernan Polo Friz ◽  
Mauro Molteni ◽  
Davide Del Sorbo ◽  
Lorenzo Pasciuti ◽  
Matteo Crippa ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Cohort Study ◽  
Elderly Patients ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort

scholarly journals Clinical characteristics and outcome of influenza virus infection among adults hospitalized with severe COVID-19: A retrospective cohort study from Wuhan, China

2020 ◽  
Author(s):  
Xunliang Tong ◽  
Xiaomao Xu ◽  
Guoyue Lv ◽  
He Wang ◽  
Anqi Cheng ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Cohort Study ◽  
Clinical Features ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Influenza Virus Infection ◽  
Clinical Feature ◽  
Risk Of Death ◽  
New City ◽  
Characteristic Features

Abstract Background Coronavirus disease 2019 (COVID-19) is an emerging infection disease that rapidly spreads worldwide. Co-infection may occur in some cases of COVID-19, like influenza virus and so on. Clinical features and outcomes of severe COVID-19 patients with co-infection of influenza virus need to be noticed.Methods Retrospective cohort study was performed and total of 140 patients with severe COVID-19 was enrolled in designated wards of Sino-French New City Branch of Tongji Hospital between Feb 8th and March 15th in Wuhan, Hubei province, China. The demographic, clinical features, laboratory indices, treatment and outcomes of these patients were collected and analyzed.Results Of 140 severe COVID-19 hospitalized patients, 73 patients were with median age of 66 years old with identification of influenza virus IgM-positive and 67 patients were with median age of 62 years old in influenza virus IgM-negative. Nearly half of severe COVID-19 patients in this research are male. Majority of the severe COVID-19 patients had chronic underlying conditions. Wheeze was the clinical feature of severe COVID-19 patients with influenza IgM-positive (26.4% vs 9.0%, P = 0.008). On contrary, fatigue or myalgia was the feature of the COVID-19 patients without IgM-positive (38.4% vs 58.2%, P = 0.019). Increased levels of ferritin and prolonging APTT were showed in severe COVID-19 patients without influenza IgM-positive compared with patients in other group with significant differences. Death rate in the group of severe COVID-19 patients with influenza IgM-positive is lower than it in other group with significant differences (4.1% vs 14.9%, P = 0.040). In univariate regression analysis, several factors were associated with higher risk of death, which included LDH, troponin, NT-proBNP, D-dimer, PT, APTT, lymphocytes, platelet and eGFR. However, influenza virus IgM positive was associated with lower risk of death.Conclusions Characteristic features of patients with severe COVID-19 with influenza virus IgM-positive were described. Co-infection may occur during the pandemic of COVID-19, and we need to improve our understanding in order to confront this crisis in the future.

scholarly journals The incidence of acute pulmonary embolism following syncope in anticoagulant-naïve patients: A retrospective cohort study

PLoS ONE ◽  
2018 ◽  
Vol 13 (3) ◽  
pp. e0193725 ◽  
Author(s):  
Danny Epstein ◽  
Gidon Berger ◽  
Noam Barda ◽  
Erez Marcusohn ◽  
Yuval Barak-Corren ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Acute Pulmonary Embolism

PS Cont’d - 66. The Incidence of Diabetes Mellitus following Pulmonary Embolism: a Retrospective Cohort study

2012 ◽  
Vol 10 (3) ◽  
pp. 145-146
Author(s):  
M.K. Sechterberger ◽  
B.A. Hutten ◽  
J.B.L. Hoekstra ◽  
P.W. Kamphuisen ◽  
J.H. de Vries
Keyword(s):  
Diabetes Mellitus ◽  
Pulmonary Embolism ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort

scholarly journals Analysis of the microbial flora in breast abscess: a retrospective cohort study conducted in the emergency department

2017 ◽  
Vol 4 (7) ◽  
pp. 2143 ◽  
Author(s):  
Ramya Ramakrishnan ◽  
Ramakrishnan V. Trichur ◽  
Sowmya Murugesan ◽  
Srihari Cattamanchi
Keyword(s):  
Staphylococcus Aureus ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Microbial Flora ◽  
Breast Abscess ◽  
Group B Streptococci ◽  
Culture Sensitivity ◽  
Group B ◽  
Age Range

Background: Breast abscess develops as a complication of lactational mastitis. Recently, there is an increase in the incidence of non-lactational breast abscess. The aim of the study was to analyse the microbial flora in the lactational and non-lactational breast abscess in the ED and to elucidate the susceptibility of flora to different antibiotics.Methods: This is a retrospective cohort study of breast abscess patients registered in the ED over two years. The case records of these patients were retrieved, and the details of their age, clinical presentation, investigation, and treatment were recorded. Specifically, the pus culture sensitivity and antibiotics used in the management of these patients were noted, and the pattern of microbiological flora analyzed.Results: A total of 124 patients were included in the study, with 97 women were categorized into lactational breast abscess, and 27 women were classified as a non-lactational breast abscess. Mean age was 24 years of age (Range 18 to 56 years). The majority of the women were young between 18 and 34 years of age (83%). The culture was grown in 92% of the patient pus specimens. Staphylococcus aureus (83%) was common organisms cultured in lactational breast abscess. Mixed Flora including Staphylococcus aureus and Group B Streptococci were grown in non-lactational breast abscess.Conclusions: Appropriate antibiotic choices are of immense importance in the management of breast abscess. Mixed flora is common in non - lactational breast abscess when compared with a lactational breast abscess. Staphylococcus Aureus is the most common isolate in both groups.

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