ESRA19-0396 Sufentanil nanotabs after laparoscopic segmental colectomy for inflammatory bowel disease: a retrospective cohort analysis

Author(s):  
L Mancel ◽  
S Coppens ◽  
A Wolthuis ◽  
D Hoogma
Author(s):  
Jéssica Martins Torres ◽  
Gabriela Santos Silva ◽  
Felipe Bertollo Ferreira ◽  
Ana Paula Hamer Sousa Clara ◽  
Felipe Welling Lorentz ◽  
...  

Introdução: A doença inflamatória intestinal (DII) representa um grupo de afecções crônicas idiopáticas que levam à inflamação do intestino. As duas principais representantesdessa doença são a Doença de Crohn (DC) e a Retocolite Ulcerativa (RCU). A crescente incidência e prevalência das doenças inflamatórias intestinais em países em desenvolvimentocomo o Brasil torna cada vez mais necessário o entendimento do comportamento epidemiológico da doença. Objetivo: Este presente estudo tem como objetivo analisar o perfil clínico epidemiológico da doença inflamatória intestinal em hospital de referência para o tratamento dessa patologia. Métodos: Trata-se de um estudo tipo coorte histórica com abordagem quantitativa, realizado no Ambulatório de Gastroenterologia do Hospital Santa Casa de Misericórdia de Vitória (HSCMV) localizado no estado do Espírito Santo. A população estudada foi adquirida após busca no sistema informatizado dos atendimentos hospitalares e ambulatoriais sob o CID-10 K50 e K51 durante o período de 01/01/2010 até 31/12/2019 (N=300). Resultados: A média de idade no momento do diagnóstico da doença inflamatória intestinal foi de 35,1 anos. A análise comparativa das variáveis epidemiológicas mostra que no grupo de DC 67,5% dos participantes tiveram pelo menos uma internação por exacerbação da doença ao longo de seu acompanhamento, contrastando com 28,9% dos portadores de RCU. Em relação a classe de medicamentos, nota-se que o grupo de RCU teve 24,7% dos participantes usando imunobiológicos durante o período analisado, o uso dessemesmo medicamento no grupo de portadores de DC foi de 63,2%. Conclusão: Este trabalho assume sua importância ao trazer dados novos da epidemiologia da DII no estado do Espírito Santo e do comportamento da doença, além de apresentar diferenças importantes da  literatura mundial, se transformando, assim, em um documento de grande importância para o serviço. Palavras chave: Doença de Crohn, Colite ulcerativa, Epidemiologia AbstractIntroduction: Inflammatory bowel disease it’s an idiopathic disorder that leads to inflammation of the gastroenteric tissue. The two main representatitves of this condition areCrohn’s Disease and Ulcerative Colitis. The increasing incidence of this disorder in developing countries such as Brazil makes the understanding of epidemiological aspects increasingly important. Objective: This article aimed to explore the clinical-epidemiological aspects of patients diagnosed with inflammatory bowel disease. Method: It’s a retrospective cohort study. The study design includes the patients diagnosed with inflammatory bowel disease seen at the gastroenterology clinic of the Hospital Santa Casa de Misericórdia de Vitória during January, 2010 to December 2019. Results: The average age at the time of the diagnosis was 35,1 years old. The analysis shows that 67,5% of the patients with Crohn’s Disease (CD) was hospitalized at least one time due to descompensation compared to 28,9% of Ulcerative Colitis (UC) patients. 24,7% of the UC participants made use of immunobiological therapy contrasted with 63,2% of CD patients. Conclusion: This article brings to light new epidemiological data and disease’s behavior regarding inflammatory bowel disease in the state of Espírito Santo besides uncovers important divergences between this study and other articles. This way, it becomes an important tool to the Gastroenterology clinic.   Keyword: Crohn disease, Colitis ulcerative, Epidemiology


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Karoline Freeman ◽  
Ronan Ryan ◽  
Nicholas Parsons ◽  
Sian Taylor-Phillips ◽  
Brian H. Willis ◽  
...  

Abstract Background Our knowledge of the incidence and prevalence of inflammatory bowel disease (IBD) is uncertain. Recent studies reported an increase in prevalence. However, they excluded a high proportion of ambiguous cases from general practice. Estimates are needed to inform health care providers who plan the provision of services for IBD patients. We aimed to estimate the IBD incidence and prevalence in UK general practice. Methods We undertook a retrospective cohort study of routine electronic health records from the IQVIA Medical Research Database covering 14 million patients. Adult patients from 2006 to 2016 were included. IBD was defined as an IBD related Read code or record of IBD specific medication. Annual incidence and 12-month period prevalence were calculated. Results The prevalence of IBD increased between 2006 and 2016 from 106.2 (95% CI 105.2–107.3) to 142.1 (95% CI 140.7–143.5) IBD cases per 10,000 patients which is a 33.8% increase. Incidence varied across the years. The incidence across the full study period was 69.5 (95% CI 68.6–70.4) per 100,000 person years. Conclusions In this large study we found higher estimates of IBD incidence and prevalence than previously reported. Estimates are highly dependent on definitions of disease and previously may have been underestimated.


2021 ◽  
Vol 3 (12) ◽  
pp. 500-506
Author(s):  
Philip R Harvey ◽  
Jayne Slater ◽  
Akram Algieder ◽  
Judith Jones ◽  
Beth Bates ◽  
...  

Background: The Toronto consensus for management of ulcerative colitis (UC) recommends early evaluation of UC patients 2 weeks after initiation on corticosteroids. A system for early evaluation of inflammatory bowel disease patients was established by specialist nurses in a secondary care centre. Aim: To compare outcomes following early evaluation to the previous service. Methods: All patients undergoing early evaluation over a 1-year period were prospectively audited and compared to a retrospective cohort of patients receiving prednisolone in the preceding year. Findings: Of 140 patients included, 76 (54.3%) underwent early evaluation. All patients in the early evaluation group received drug education and details of the nurse helpline (17.1% of patients did not already have this). Of patients, 81.6% were prescribed Adcal, and 83.9% were on 5-aminosalicylates. Fewer admissions were observed within 6 months following early evaluation (8.6% vs. 23.4%, p=0.013). Conclusion: Multiple benefits of early evaluation were observed, including a potential reduction in hospital admissions.


2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S255-S255
Author(s):  
C G Heisler ◽  
K Gawdat ◽  
N Nazer ◽  
M Stewart ◽  
B Currie ◽  
...  

Abstract Background Patients living with chronic illnesses require long-term and often repeated interactions with the healthcare system. inflammatory bowel disease (IBD) is an incurable, chronic gastrointestinal disease which frequently flares and remits. The nurse navigator (NN) serves as the point of first contact for IBD connecting patients with their multidisciplinary care team in order to facilitate and expedite assessment, treatment and navigation through the healthcare system with the goal of improving disease-related outcomes while reducing healthcare system burden. The aim of this study was to assess the impact of implementation of an IBD NN role within a multidisciplinary IBD Medical home on access to care, disease-related outcomes, patient satisfaction with care, and healthcare resource use. Methods This was a retrospective cohort study comparing an IBD patient population that had access to a 24/7 NN-led helpline to a reference population who did not have access to such a service. Data between August 2017 and October 2019 were extracted from patient charts. Distribution of the number of flares and time to clinical assessment between the NN exposed cohort and a non-NN exposed cohort are planned using multivariate analysis. This is a preliminary description of the NN-exposed cohort only. Results Preliminary results identified a total of 643 patients in the NN-exposed cohort. The majority of our NN-exposed population were female (64.3%). The mean age was 46.42 ± 16.86 years. Sixty-five per cent of patients had CD, 33% UC and 2% IBDU. Of the 729 calls extracted, care coordination (39%) was the most frequent indication for calls followed by flare (25%), and medication education (16%). Patients made the majority (52.8%) of calls compared with NN initiated calls (47.2%). The mean number of calls per patient was 2.64 ± 2.51 (range 1–18) during the study period. Time to clinic assessment post flare call was on average 10.22 ± 8.51 days. Conclusion These results are descriptive of the NN-exposed cohort. Data comparing outcomes amongst the NN-exposed cohort to the non-exposed cohort will be presented at ECCO.


Sign in / Sign up

Export Citation Format

Share Document