P130 Prognostic value of the initial chest computerised tomography scan at one year following infection in an ethnically diverse cohort of patients admitted to hospital for COVID-19

Significant cognitive impairment has been found in 20—30% of patients with clinically isolated syndromes suggestive of multiple sclerosis. In this study we aimed to assess the prognostic value of the presence of cognitive impairment for the conversion to multiple sclerosis in patients with clinically isolated syndromes. All patients with clinically isolated syndromes consecutively referred to our centre since 2002 and who had been followed-up for at least one year underwent cognitive assessment through the Rao’s Battery and the Stroop test. Possible predictors of conversion to clinically definite multiple sclerosis were evaluated through the Kaplan Meier curves and Cox regression analysis. A total of 56 patients (41 women; age 33.2 ± 8.5 years; expanded disability scale score 1.2 ± 0.7) were recruited. At baseline, 32 patients (57%) fulfilled McDonald’s criteria for dissemination in space. During the follow-up (3.5 ± 2.3 years), 26 patients (46%) converted to a diagnosis of multiple sclerosis. In particular, 64% of patients failing ≥ 2 tests and 88% of patients failing ≥ 3 tests converted to multiple sclerosis. In the Cox regression model, the failure of at least three tests (HR 3.3; 95% CI 1.4—8.1; p = 0.003) and the presence of McDonald’s dissemination in space at baseline (HR 3.8; 95% CI 1.5—9.7; p = 0.005), were found to be predictors for conversion to multiple sclerosis. We conclude that cognitive impairment is detectable in a sizable proportion of patients with clinically isolated syndromes. In these subjects cognitive impairment has a prognostic value in predicting conversion to multiple sclerosis and may therefore play a role in therapeutic decision making.

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121 Prognostic value of normal adenosine stress cardiac magnetic resonance imaging exams – one year follow-up results of a prospective study

Journal of Cardiovascular Magnetic Resonance ◽

10.1186/1532-429x-10-s1-a22 ◽

2008 ◽

Vol 10 (S1) ◽

Cited By ~ 1

Author(s):

Guenter Pilz ◽

Andrea Jeske ◽

Markus Klos ◽

Eman Ali ◽

Berthold Hoefling ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Cardiac Magnetic Resonance ◽

Magnetic Resonance ◽

Prospective Study ◽

Prognostic Value ◽

Resonance Imaging ◽

Stress Cardiac Magnetic Resonance ◽

One Year ◽

A Prospective Study

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Extrém magas B típusú natriureticus prohormon prognosztikai szerepe a szívelégtelenség miatt kezelt betegek kórházi halálozására

Orvosi Hetilap ◽

10.1556/650.2017.30761 ◽

2017 ◽

Vol 158 (20) ◽

pp. 779-782

Author(s):

Béla Bózsik ◽

Erzsébet Nagy ◽

Miklós Somlói ◽

János Tomcsányi

Keyword(s):

Heart Failure ◽

Hospital Mortality ◽

Hospital Stay ◽

Natriuretic Peptide ◽

Natriuretic Peptides ◽

Prognostic Value ◽

Response To Therapy ◽

Cardiology Department ◽

The Difference ◽

One Year

Abstract: Introduction: Patients hospitalized for heart failure have a very high in-hospital as well as one-year mortality. Natriuretic peptides play both a diagnostic and a prognostic role in this disease. Changes of natriuretic peptide levels in response to therapy are a well-known prognostic marker. Regarding in-hospital mortality, however, little is known about the prognostic value of extremely high levels of natriuretic peptides measured on admission. Aim: To decide whether extremely high levels of B-type natriuretic peptide have a prognostic value with regard to in-hospital mortality. Method: NT-proBNP levels on admission and in-hospital mortality were extracted retrospectively from the data of patients treated with heart failure in the cardiology department of the Hospital of St. John of God in Budapest. We separately analyzed the data of patients hospitalized for heart failure in 2015 with extremely high initial NT-proBNP levels. The cut-off value in this regard was 10 000 ng/l. We also analyzed the comorbidities of these patients. Results: The median NT-proBNP level of those patients who survived beyond the index hospital stay in the last 10 years was 4842 ng/l, whereas the median NT-proBNP level of those 182 patients who died during their hospital stay was 10 688 ng/l (p<0.001). In the year 2015, we treated 118 patients with an NT-proBNP level above 10 000 ng/l. Thirteen of these patients died, which means that their in-hospital mortality exceeded 10%. In comparison, the in-hospital mortality of all heart failure patients was 5.8%. The difference of median NT-proBNP levels of surviving versus deceased patients in this group with extremely high NT-proBNP levels was no longer significant (17 080 ng/l vs. 19 152 ng/l). Conclusions: Patients with an NT-proBNP level of >10 000 ng/l on admission have a significantly higher in-hospital mortality. The difference of NT-proBNP levels of surviving versus deceased patients in the group with admission NT-proBNP levels >10 000 ng/l is no longer significant. We could not identify any etiological factors that would explain these extremely high NT-proBNP levels or the excess in-hospital mortality. Orv Hetil. 2017; 158(20): 779–782.

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Computerised tomography scan in multi-drug-resistant versus extensively drug-resistant tuberculosis

Polish Journal of Radiology ◽

10.5114/pjr.2020.93123 ◽

2020 ◽

Vol 85 (1) ◽

pp. 39-44 ◽

Cited By ~ 2

Author(s):

Payam Mehrian ◽

Poopak Farnia ◽

Dina Jalalvand ◽

Mostafa Chamani ◽

Mahmood Bakhtiyari

Keyword(s):

Drug Resistant ◽

Computerised Tomography ◽

Drug Resistant Tuberculosis ◽

Resistant Tuberculosis ◽

Extensively Drug Resistant ◽

Tomography Scan

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Direct traumatic optic neuropathy in a temporal laceration: A case report

Trauma ◽

10.1177/1460408615624726 ◽

2016 ◽

Vol 19 (1) ◽

pp. 66-68

Author(s):

Simon WJ Grant ◽

Moorthy Halsnad ◽

Steve Colley ◽

Ian Sharp

Keyword(s):

Optic Neuropathy ◽

Penetrating Trauma ◽

Temporal Region ◽

Computerised Tomography ◽

Traumatic Optic Neuropathy ◽

Maxillofacial Region ◽

Case Presentation ◽

Orbital Wall ◽

The Right ◽

Tomography Scan

Facial lacerations are a common presentation in emergency departments. It is important to appreciate the mechanism of injury and the anatomy of structures involved in penetrating lacerations in the maxillofacial region. A 65-year-old man suffered an accidental penetrating injury with a sharp kitchen knife to the right temporal region. There was a single laceration to the right temporal region. The right eye had no perception to light, a total afferent and efferent pupillary defect and partial ophthalmoplegia. Computerised tomography scan revealed signs of penetration through the skin, temporalis, postero-lateral orbital wall and orbital apex. There was no injury to the globe or either retrobulbar or intracranial haemorrhage. A diagnosis of direct traumatic optic neuropathy was made following consultation with opthalmology and neurosurgery teams. Only two similar cases of penetrating trauma in the temporal region resulting in direct traumatic optic neuropathy have been identified in the literature. This case presentation highlights the structures that are at risk of damage from penetrating trauma in the maxillofacial region.

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Quantitative Computerised Tomography Scan Can Diagnose, Quantitate and Locate Pulmonary Emphysema Non-Invasively in Humans

Respiration ◽

10.1159/000195081 ◽

1986 ◽

Vol 50 (1) ◽

pp. 3-4 ◽

Cited By ~ 1

Author(s):

D.C. Flenley ◽

W. MacNee ◽

G. Gould ◽

A. Redpath ◽

J.J.K. Best ◽

...

Keyword(s):

Pulmonary Emphysema ◽

Computerised Tomography ◽

Tomography Scan

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Role of Multidetector Computerised Tomography in Evaluation of Proptosis

Nepalese Journal of Radiology ◽

10.3126/njr.v9i2.27421 ◽

2019 ◽

Vol 9 (2) ◽

pp. 24-31

Author(s):

Elina Shrestha ◽

Narayan Bikram Thapa ◽

Shankar Bahadur Singh Rajbhandari

Keyword(s):

Predictive Value ◽

Clinical Information ◽

Cross Sectional Study ◽

Computerised Tomography ◽

Cross Sectional ◽

Female Ratio ◽

Male Female Ratio ◽

One Year ◽

Female Male Female

Introduction: Proptosis is defined as bulging of eye anteriorly out of the orbit. Our main objective was to analyze the pattern of computerised tomographic findings in evaluation of proptosis. Computerised tomography (CT) is noninvasive, easily accessible, affordable and reliable imaging which helps in early diagnosis and prompt treatment. Methods: A descriptive cross sectional study of total 58 patients presenting with proptosis referred to our department of radiology for computerised tomography evaluation during one year period were undertaken into study. The clinical information provided by ophthalmologist also helped our study to derive into conclusion. SPSS version 20 software was used for statistical data analysis. Results: Out of 58 patients, the most common cause of proptosis was neoplasm constituting of 25 cases (43.1%). Retinoblastoma was the commonest orbital tumor. Out of remaining cases, 15 (25.8%) were infective, 14 (24.1%) were inflammatory, two (3.44%) were traumatic and remaining two cases (3.44%) had no definitive cause for proptosis. Bilateral proptosis was commonly associated with thyroid ophthalmopathy. Among the subjects 32 were male, 26 were female. Male: Female ratio was 1:1.23. Age group was ranging from 1 month to 73 years.Mean age was 26.4 ± 22 years. Conclusions: Computerised tomography has an important role in distinguishing the different types of lesions based on their characteristics, location and extension prior to undertaking definitive surgical and medical treatment. Overall accuracy of CT in our study was 81%, sensitivity of 82.6%, specificity of 80.6%, positive predictive value of 76% and negative predictive value of 86.2%.

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