Chromoblastomycosis in two giant ditch frogs also known as mountain chicken frogs (Leptodactylus fallax)

2019 ◽  
Vol 7 (3) ◽  
pp. e000691
Author(s):  
Martina Croci ◽  
Stefanie Klausmann ◽  
Jean-Michel Hatt ◽  
Sarah Schmitt ◽  
Monika Hilbe
Keyword(s):  
Sudden Death ◽  
Skin Disease ◽  
Fungal Pathogen ◽  
Systemic Disease ◽  
Skin Lesions ◽  
Post Mortem ◽  
Human Beings ◽  
Skeletal Musculature ◽  
Chronic Skin ◽  
Chronic Skin Disease

Because of sudden death of several frogs following the renewal of a terrarium, two giant ditch frogs (Leptodactylus fallax) were submitted for post-mortem examination. The animals displayed extensive erythematous to ulcerative skin lesions as well as multiple granulomas in the liver, kidney and skeletal musculature. In skin lesions as well as in the brownish granulomas, pigmented fungal sclerotic bodies were found in addition to pigmented hyphal structures, though less common. The fungal pathogen, although not further classified in this study was identified as the etiological agent for chromoblastomycosis (synonym: chromomycosis), a leading cause of fatal systemic disease in poikilothermic animals. It is also a cause of chronic skin disease in human beings and therefore a potential zoonotic agent.

Paracrystalline Aggregates of Psoriatic Keratin and Their Relation to Normal Keratin Structure

1985 ◽  
Vol 43 ◽  
pp. 680-681
Author(s):  
S. Trachtenberg ◽  
P.M. Steinert ◽  
B.L. Trus ◽  
A.C. Steven
Keyword(s):  
Cell Death ◽  
Stratum Corneum ◽  
Intermediate Filament ◽  
Skin Disease ◽  
Amorphous Matrix ◽  
Terminal Differentiation ◽  
Proteolytic Degradation ◽  
Horny Layer ◽  
Chronic Skin ◽  
Chronic Skin Disease

During terminal differentiation of vertebrate epidermis, certain specific keratin intermediate filament (KIF) proteins are produced. Keratinization of the epidermis involves cell death and disruption of the cytoplasm, leaving a network of KIF embedded in an amorphous matrix which forms the outer horny layer known as the stratum corneum. Eventually these cells are shed (desquamation). Normally, the processes of differentiation, keratinization, and desquamation are regulated in an orderly manner. In psoriasis, a chronic skin disease, a hyperkeratotic stratum corneum is produced, resulting in abnormal desquamation of unusually large scales. In this disease, the normal KIF proteins are diminished in amount or absent, and other proteins more typical of proliferative epidermal cells are present. There is also evidence of proteolytic degradation of the KIF.

The Impact of Chronic Skin Disease on Daily Life (ISDL): a generic and dermatology-specific health instrument

2007 ◽  
Vol 0 (0) ◽  
pp. 071115063928006-??? ◽  
Author(s):  
A.W.M. Evers ◽  
P. Duller ◽  
P.C.M. van de Kerkhof ◽  
P.G.M. van der Valk ◽  
E.M.G.J. de Jong ◽  
...  
Keyword(s):  
Skin Disease ◽  
Daily Life ◽  
Chronic Skin ◽  
The Impact ◽  
Chronic Skin Disease ◽  
Specific Health

Managing chronic skin disease

1999 ◽  
Vol 10 (12) ◽  
pp. 22-24
Author(s):  
Jean Watkins ◽  
Peter Goodwin ◽  
Denise Slade
Keyword(s):  
Skin Disease ◽  
Chronic Skin ◽  
Chronic Skin Disease

scholarly journals The Role of Allergens in Atopic Dermatitis

2020 ◽  
Author(s):  
Suna Asilsoy ◽  
Serdar Al
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Allergic Diseases ◽  
Skin Lesions ◽  
Atopic Diseases ◽  
Chronic Skin ◽  
Genetic And Environmental Factors ◽  
Inhalant Allergens ◽  
Chronic Skin Disease

Atopic dermatitis (AD) is a chronic skin disease caused by genetic and environmental factors. Often it begins in early childhood. It is located at the first step of the process we refer to as atopic march. This feature is a precursor of the development of other allergic diseases such as asthma and allergic rhinitis. Especially in patients with atopy of food and inhalant allergens, the occurrence of other atopic diseases is more common. Although the role of these sensitivities in AD is controversial, it has been determined that some patients may trigger eczematous skin lesions. In this report, the role of allergens in atopic dermatitis are reviewed in the light of current literature.

Rosacea

2019 ◽  
Vol 12 (5) ◽  
pp. 271-275
Author(s):  
Apurva Mishra ◽  
Shanu Mishra
Keyword(s):  
Primary Care ◽  
Skin Disease ◽  
Caucasian Population ◽  
Northern Europe ◽  
Southern Europe ◽  
Treatment Resistant ◽  
Sebaceous Glands ◽  
The Face ◽  
Chronic Skin ◽  
Chronic Skin Disease

Rosacea is a common, chronic skin disease that affects the facial pilo-sebaceous glands. It is characterised by erythema, flushing and sometimes papules. It typically affects the convex surfaces of the face, most commonly the forehead, cheeks, chin and nose. Rosacea predominantly affects the Caucasian population, with prevalence being higher in northern Europe than southern Europe. It is three times more common in females and peaks between 30 and 60 years of age. Rosacea can usually be well managed with topical or oral treatments in primary care, although some forms of rosacea or treatment-resistant cases may need specialist input.

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