Effect of feeding 5 per cent glucose solution or milk replacer to newborn piglets on intestinal permeability to macromolecules

1988 ◽  
Vol 123 (15) ◽  
pp. 395-397 ◽  
Author(s):  
L. Vellenga ◽  
T. Wensing ◽  
H. Breukink
2020 ◽  
pp. 1-8
Author(s):  
Charlotte Amdi ◽  
Marie Louise M. Pedersen ◽  
Joanna Klaaborg ◽  
Laura J. Myhill ◽  
Maiken N. Engelsmann ◽  
...  

Abstract Hyperprolific sows rear more piglets than they have teats, and to accommodate this, milk replacers are often offered as a supplement. Milk replacers are based on bovine milk, yet components of vegetable origin are often added. This may reduce growth, but could also accelerate maturational changes. Therefore, we investigated the effect of feeding piglets a milk replacer with gradually increasing levels of wheat flour on growth, gut enzyme activity and immune function compared with a diet based entirely on bovine milk. The hypothesis tested was that adding a starch component (wheat flour) induces maturation of the mucosa as measured by higher digestive activity and improved integrity and immunity of the small intestines (SI). To test this hypothesis, piglets were removed from the sow at day 3 and fed either a pure milk replacer diet (MILK) or from day 11 a milk replacer diet with increasing levels of wheat (WHEAT). The WHEAT piglets had an increased enzyme activity of maltase and sucrase in the proximal part of the SI compared with the MILK group. There were no differences in gut morphology, histopathology and gene expression between the groups. In conclusion, the pigs given a milk replacer with added wheat displayed immunological and gut mucosal enzyme maturational changes, indicatory of adaptation towards a vegetable-based diet. This was not associated with any clinical complications, and future studies are needed to show whether this could improve responses in the subsequent weaning process.


2015 ◽  
Vol 18 (1) ◽  
pp. 91-99 ◽  
Author(s):  
A. Lepczyński ◽  
A. Herosimczyk ◽  
M. Ożgo ◽  
W.F. Skrzypczak

Abstract The study was undertaken to determine the effect of feeding milk or milk-replacer on the blood plasma proteome and lipid profile in calves during the second week of life. Feeding milk-replacer significantly decreased the expression of plasma apoA-I. Age of calves affected apoA-I expression, which was higher on the 8th than on the 11th and 14th day of life. A significant effect of interaction between diet and age was also observed. The expression of apoA-IV, was significantly affected by diet and was lower in calves fed milk replacer. Expression of this protein was significantly lower at the 8th day of life and was up-regulated in the calves fed milk-replacer at the second week of life. Calves fed milk-replacer had greater expression of haptoglobin, which differed significantly between days of blood sampling, being higher on the 8th than on the 11th and 14th day. The interactive effect of diet and age affected haptoglobin expression, which was successively down-regulated in calves fed milk replacer. Diet had a significant effect on the plasma lipid profile. Animals fed milk had a greater concentration of TC, HDLC and LDLC. The composition of milk-replacer, especially fat source, is probably the main factor that affects expression of proteins involved in cholesterol metabolism and level of components of lipid profile in calves fed formula. We claim that the initially increased level of haptoglobin, followed by its decrease during the second week of life in calves fed milk-replacer may indicate the presence of short-term stress induced by changes in the feeding system.


2015 ◽  
Vol 58 (1) ◽  
pp. 229-235 ◽  
Author(s):  
G. Novotni-Dankó ◽  
P. Balogh ◽  
L. Huzsvai ◽  
Zs. Győri

Abstract. The aim of the present study was to investigate the effect of liquid milk supplement on litter performance (weight development of the piglets, weaning weight and mortality) and on sow back-fat thickness change during the suckling period. Data were collected from 150 litters, with the weight of a total of 1709 piglets measured at birth, at 14 days of age and at weaning (28 days), respectively. Sow (n = 150) back-fat depth was measured the day before farrowing, 14 days after farrowing and at weaning. In the control group (n = 363), the piglets were suckled and got pre-starter feed from day 10. In the four experimental groups (MS1; MS2; MS2 and MS4; n = 1346), the piglets received additional milk replacer in various concentrations from the 10th day of life. While there were no significant differences in birth weight between the control and experimental groups, we did find significant differences between the 14-day weights and weaning weights. The milk supplement significantly reduced mortality compared to the control (11.6 vs. 4.9; 5.9, 8.9; 8.3 %). However, there were no statistically significant differences between litter homogeneity data, based on the CV% of piglet weight. Three experimental groups (MS1, MS2 and MS4) were more homogenous compared to the control group at weaning (25.3 vs. 20.9; 20.3; 20.3 CV%). Based on the examination of sow back-fat thickness reduction, there were significant differences between the control (C) and MS3 groups (7.61 vs. 5.57 mm reduction, P < 0.05) during the suckling period. These results demonstrate the advantage of milk replacer on weaning weight. Litter homogeneity, piglet mortality and back-fat thickness of the sows were affected by providing milk replacer to the piglets during the suckling period.


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