NEW CONSIDERATIONS IN ORGANOGERMANIUM-SULPHUR CHEMISTRY

1963 ◽  
Vol 41 (5) ◽  
pp. 1276-1280 ◽  
Author(s):  
Malcolm C. Henry ◽  
Wenzel E. Davidson
Keyword(s):  
Chemical Properties ◽  
Group Iv ◽  
Physical And Chemical Properties ◽  
Sulphur Compounds ◽  
New Compounds ◽  
Physical And Chemical ◽  
First Time ◽  
And Chemical Properties

The successful synthesis of sodium triphenylgermanethiol (1), (C6H5)3GeSNa, and disodium diphenylgermanedithiol, (C6H5)2Ge(SNa)2, have made it possible to carry out reactions with RX type compounds yielding a variety of organogermanium-sulphur compounds. In addition, triphenylgermanethiol, (C6H5)3GeSH, has been synthesized for the first time. Reactions of these compounds are related to analogous group IV element compounds. Physical and chemical properties of these new compounds are also discussed.

Sila-Pharmaka, 9. Mitt. [1] Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, I / Sila-Drugs, 9th Communication [1] Preparation and Properties of Silicon Compounds with Potential Curare-Like Activity, I

1978 ◽  
Vol 33 (4) ◽  
pp. 412-416 ◽  
Author(s):  
Reinhold Tacke ◽  
Roland Niedner
Keyword(s):  
Mass Spectroscopy ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Organosilicon Compounds ◽  
Silicon Compounds ◽  
H Nmr ◽  
Toxicological Data ◽  
Physical And Chemical ◽  
First Time ◽  
And Chemical Properties

Abstract Organosilicon compounds 8, 9 and 10 with potential curare-like action and their precursors 5, 6 and 7 were synthesized for the first time. 5−10 were characterized by their physical and chemical properties, and their structures were confirmed by analyses, 1 H NMR and mass spectroscopy (only for 5−7). The pharmacological and toxicological data of 8, 9 and 10 are reported.

Synthese und Eigenschaften von Alkyloxi-und Aryloxi-substituierten Trithiadiborolanen / Synthesis and Properties of Alkoxi and Aryloxi Substituted Trithiadiborolanes

1981 ◽  
Vol 36 (11) ◽  
pp. 1444-1450 ◽  
Author(s):  
Max Schmidt ◽  
Erich Sametschek
Keyword(s):  
Thermal Stability ◽  
Nmr Spectra ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
H Nmr ◽  
New Compounds ◽  
Physical And Chemical ◽  
Thermal Stability Of ◽  
And Chemical Properties

Abstract The first examples of the hitherto unknown 1,2,4-Trithia-3,5-diborolanes with B-O-C-bonds have been synthesized and characterised. The diiodo substituted ring (2) reacts with 2,6-dimethylphenol, to form 3,5-bis-(2,6-dimethylphenyloxi)-1,2,4-trithia-3,5-di-borolane (3) and HI. 3,5-Diethoxi-1,2,4-trithia-3,5-diborolane, 5, and C2H5I are formed via the cleavage of diethylether by 2. From 2 and diisopropylether, the corresponding 3,5-diisopropyloxi-1,2,4-trithia-3,5-diborolane (6) is formed. The unsymmetrical ethers methyl-t-butylether and methylphenylether undergo reactions with 2 resulting in the formation of 3,5-dimethyloxi-1,2,4-trithia-3,5-diborolane (8) (besides t-C4H9I) and 3,5-diphenyloxi-1,2,4-trithia-3,5-diborolane (10) (besides CH3I). The thermal stability of the new compounds is increasing with increasing size of R in the -OR group and from aliphatic to aromatic R in this group. IR, Raman, 1H NMR and 11B NMR spectra of the compounds are reported as well as some physical and chemical properties.

scholarly journals Some transformations and physicochemical properties of new S-substituted 5-thiophene-(3-ylmethyl)-4R-1,2,4-triazole-3-thiols

2021 ◽  
pp. 50-56
Author(s):  
А. В. Хільковець
Keyword(s):  
Alkaline Medium ◽  
Chemical Properties ◽  
Monochloroacetic Acid ◽  
Esterification Reaction ◽  
Physical And Chemical Properties ◽  
Analysis Methods ◽  
New Compounds ◽  
Physical And Chemical ◽  
Derivatives Of ◽  
And Chemical Properties

Nitrogen-containing heterocyclic compounds are widely represented in modern organic chemistry. A special place among the huge number of substances presented is occupied by derivatives of 1,2,4-triazole due to their uniqueness and prospects. In recent years, these derivatives have remained the object of close attention of both synthetic chemists and researchers engaged in the search for new biologically active substances of a wide spectrum of action, the synthesis of optical materials, dyes, corrosion inhibitors, veterinary drugs, etc. It is known from the literature that the combination of the aromatic heterocycle of thiophene and 1,2,4-triazole is a promising area for research. The result of such combinations is a number of compounds obtained with fairly high yields and a wide range of activities. Thus, further chemical modification of 1,2,4-triazole derivatives by additional administration of a typical thiophene pharmacophore is an urgent task. The aim of the study is to obtain new compounds in a number of S-substituted 5-thiophene-(3-ylmethyl)-4R-1,2,4-triazole-3-thiols and study their physico-chemical properties using complex analysis methods. The study of the physical and chemical properties of the compounds obtained was carried out according to methods that meet the standards of the state pharmacopoeia of Ukraine. The synthesis of new compounds was carried out according to generally accepted methods. The previously obtained 5-thiophene-(3-ylmethyl)-4h-1,2,4-triazole-3-thiol and 5-thiophene-(3-ylmethyl)-4-phenyl-1,2,4-triazole-3-thiol were used as starting compounds. Preparation of thioethanones was performed in an alkaline medium in the presence of methanol. The acids were obtained in an alcohol-alkaline medium with the addition of monochloroacetic acid. To obtain esters, two conventional methods were used. The first method is based on the alkylation in an alkaline-alcohol medium of the starting thiols with isopropyl ester of monochloroacetic acid. The second method is the classical esterification reaction. To confirm the structure and study of the physical and chemical properties, all the resulting compounds were crystallized. As a result, some new compounds that were not previously described were obtained, namely: thioethanones, thioacetamides, thioacetic acids, thioacetates, and a number of other thiopo-derivatives of these initial compounds. The structure and individuality of the obtained molecules were confirmed by elemental analysis (CHNS), IR and 1H NMR spectra. A number of new S-derivatives of 5-thiophene-(3-ylmethyl)-4R-1,2,4-triazole-3-thiols have been obtained. The physical and chemical properties of the obtained compounds are determined and their structure is confirmed using modern analysis methods. Some compounds will be transferred for further research.

scholarly journals STUDY OF COMPOSITION, PHYSICAL AND CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITY OF POLYSACCHARIDE COMPLEX OF ARCTIUM LAPPA LEAVES

2017 ◽  
Vol 25 (1) ◽  
pp. 42-48
Author(s):  
I A. Sychev ◽  
D G. Kokina
Keyword(s):  
Chemical Properties ◽  
Erythrocyte Membranes ◽  
Physical And Chemical Properties ◽  
Qualitative Composition ◽  
Arctium Lappa ◽  
Polysaccharide Complex ◽  
Healthy Donors ◽  
Physical And Chemical ◽  
First Time ◽  
And Chemical Properties

A method of isolation of polysaccharide complex from the leaves of Burdock (Arctium lappa L.) is described in the article. For the first time the qualitative composition of this complex was determined, belonging to the group of heteroglycans. Some of physical and chemical properties of polysaccharide complex were studied. It is shown that polysaccharide complex increases catalase activity and peroxide resistance of the erythrocyte membranes of healthy donors. The study found that polysaccharide complex of Burdock improves physical performance of test animals.

THE BLOOM AND TOXICITY OF CYANOBACTERIA IN LAKE SEVAN

2020 ◽  
Vol 54 (2 (252)) ◽  
pp. 168-176
Author(s):  
L.R. Hambaryan ◽  
L.G. Stepanyan ◽  
M.V. Mikaelyan ◽  
Q.G. Gyurjyan
Keyword(s):  
Algal Blooms ◽  
Littoral Zone ◽  
Algal Bloom ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Lake Sevan ◽  
Phosphate Ions ◽  
Physical And Chemical ◽  
First Time ◽  
And Chemical Properties

Seasonal hydrochemical, hydrophysical, and phytoplankton studies were conducted in a littoral zone of Lake Sevan in 2019. It is known that in recent years widespread algal blooms were usually started from the littoral zone of Big Sevan, and then spread towards the pelagic zone of the lake. The bloom was mainly caused by species belonging to the genus Dolichospermum (previously Anabaena). Our study has revealed that the physical and chemical properties of water were changed as a result of algal bloom. Particularly, the transparency of water and concentration of dissolved oxygen decreased, while the concentrations of ammonium, nitrite and phosphate ions increased. For the first time, the presence of the toxins microcystin and anatoxin-a was recorded in the lake.

scholarly journals Synthesis and structural features of 5-(4-(tert-butyl) phenyl)-4-((R)amino)-4H-1,2,4-triazole-3-thiols

2018 ◽  
pp. 60-65
Author(s):  
I. I. Aksyonova-Seliuk ◽  
O. I. Panasenko ◽  
E. G. Knysh
Keyword(s):  
Chemical Structure ◽  
Chemical Properties ◽  
Biologically Active ◽  
Physical And Chemical Properties ◽  
Tert Butyl ◽  
New Compounds ◽  
Physical And Chemical ◽  
Derivatives Of ◽  
Active Substances ◽  
And Chemical Properties

Chemistry of heterocyclic compounds is one of the most popular sector in organic chemistry. Scientists allocate among them a class of derivatives of 1,2,4-triazole. This class of compounds attracts attention his broad spectrum of biological activity. There are antiviral, anti-inflammatory, anti-tubercular, antimicrobial, antioxidant, actoprotective, anti-cancer and other activities. The derivatives of 1,2,4-triazole have one more important advantage. It is low toxicity. This properties do this class of derivatives promising for researches their chemical structure and biological activity and purposeful search of biologically active substances. The purpose of the work is synthesis of 5-(4-(tert-butyl)phenyl)-4-((R)amino)-4H-1,2,4-triazoles-3-thiols from appropriate ylidene derivatives of 4-amino-5-(4 (tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol and research of their physical and chemical properties. The objects of research were 10 new compounds, derivatives of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol. These compounds are the crystal substances which are odorless, insoluble in water and soluble in organic solvents. Investigation of the physical and chemical properties of this compounds was carried out according to the methods listed in the State Pharmacopoeia of Ukraine. The melting temperature of synthesized compounds was determined by device OptiMelt Stanford Research Systems MPA100. The structure of the compound was confirmed by 1H-NMR spectroscopy (Mercury 400) and gas chromatography-mass spectrometry (Agilent 1260 Infinity HPLC). 10 new compounds, derivatives of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol, were synthesized in a study. The chemical structure of the new compounds was confirmed by modern instrumental methods of analysis. Results of the done work can be use in the future search of biologically active substances.

scholarly journals Anatomical characterization, physical, and chemical properties of wood of Quercus macdougallii Martínez, endemic species of the Sierra Juárez of Oaxaca, Mexico

BioResources ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. 5975-5998
Author(s):  
Faustino Ruiz-Aquino ◽  
Lizbeth Luna-Bautista ◽  
Aremi E. Luna-Bautista ◽  
Wenceslao Santiago-García ◽  
Luis F. Pintor-Ibarra ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Physical Properties ◽  
Endemic Species ◽  
Basic Density ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Cellulose Pulp ◽  
Physical And Chemical ◽  
First Time ◽  
And Chemical Properties

The anatomical characteristics and the physical and chemical properties of wood of Quercus macdougallii Martínez are presented for the first time. Q. macdougallii Martínez is an endemic species of the Sierra Juarez of Oaxaca. The microscopic characteristics were described in preparations of typical cuts and dissociated material. The physical properties were evaluated according to the ASTM D 143-94 standard in sapwood and heartwood specimens. The measurable elements and physical properties were classified according to the mean. With the measurable elements, the paper pulp quality index was determined. In sapwood and heartwood, the basic chemical composition was determined. The wood of Q. macdougallii presented a pronounced grain, a thick texture, and a straight thread. Fibers, fibrotracheids, uniseriate, multiseriate, and aggregate rays were found. Basic density 0.55 g cm-3 in sapwood and 0.61 g cm-3 in heartwood is classified as moderately heavy and heavy, respectively. The saturation point of the fiber is classified as high. Based on its physical properties, Q. macdougallii wood can be used in the manufacture of furniture, veneer, floors, tool handles, and construction. Based on the pulp quality indices and chemical composition, this wood could be used to obtain cellulose pulp for paper.

scholarly journals Hayıt (Vitex agnus-castus L.) Ballarının Uçucu Bileşenlerinin ve Duyusal Özelliklerinin Tanımlanması

2021 ◽  
Vol 9 (3) ◽  
pp. 621-631
Author(s):  
Ceyda Dadalı
Keyword(s):  
Volatile Compounds ◽  
Volatile Compound ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Dimethyl Sulphide ◽  
Sulphur Compounds ◽  
Agnus Castus ◽  
Bitter Almond ◽  
Physical And Chemical ◽  
And Chemical Properties

In this study, it was aimed to characterize some physical and chemical properties, volatile compounds and sensory properties of chaste honey produced in Aydın, Çanakkale, İzmir and Muğla provinces. A total of 16 different volatile compounds (4 aldehydes, 3 furans, 2 alcohol, 2 sulphur compounds, 2 terpenes, 1 alkane, 1 benzenic compound and 1 ketone) were identified in the evaluated chaste honeys. It was determined that common volatile compounds of chaste honeys were dimethyl sulphide, octane, nonanal, 2-furancarboxaldehyde, 2-ethyl-1-hexanol, 1- (2-furanyl) -ethanone, benzaldehyde, 5-methyl-2-furancarboxaldehyde, and benzenacetaldehyde. Benzenacetaldehyde was the most abundant volatile compound in all chaste honeys, followed by benzaldehyde and 2-furancarboxaldehyde. As a result of the sensory evaluation, floral, fruity, caramel-like, bitter almond, fermented, animal-like, spicy, waxy, and woody aroma characters, sweet and sour taste characters and astringent mouthfeeling were detected in chaste honeys. The floral, fruity, caramel-like, sweet, and sour characters were intensely perceived in all samples.

ENZYMES OF MARINE ALGAE: II. ISOLATION AND IDENTIFICATION OF 3-HYDROXYTYRAMINE AS THE PHENOLASE SUBSTRATE IN MONOSTROMA FUSCUM

1966 ◽  
Vol 44 (5) ◽  
pp. 605-608 ◽  
Author(s):  
R. D. Tocher ◽  
J. S. Craigie
Keyword(s):  
Green Alga ◽  
Marine Algae ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Natural Substrate ◽  
Fresh Weight ◽  
Isolation And Identification ◽  
Physical And Chemical ◽  
First Time ◽  
And Chemical Properties

3-Hydroxytyramine (dopamine; 3, 4-dihydroxyphenylethylamine) is reported for the first time as an algal constituent. It was isolated and crystallized in approximately 0.3% of the fresh weight of the green alga, Monostroma fuscum. The identity was established by the comparison of its physical and chemical properties with those of an authentic specimen. 3-Hydroxytyramine is the principal phenol and the natural substrate for phenolase in this organism.

New Metal -Pentafluorothiophenol Compounds

1978 ◽  
Vol 33 (2) ◽  
pp. 149-150 ◽  
Author(s):  
D. M. Kaminaris ◽  
A. G. Galinos
Keyword(s):  
Ir Spectra ◽  
Analytical Data ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Nonaqueous Solutions ◽  
New Compounds ◽  
Physical And Chemical ◽  
And Chemical Properties

In the present paper the reactions of pentafluorothiophenol with nonaqueous solutions (absolute n-hexane) of anhydrous AlCl3, FeBr3, RhCl3 and CrCl3 are described. Analytical data, some physical and chemical properties and the IR spectra of the new compounds are reported and discussed

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