Chemical and biological properties of some oxindolidyl-3-methines
Keyword(s):
Several 1-methyloxindohdyl-3-methines have been synthesized, either by condensation of 1-methyloxindole with an aldehyde, or by a Wittig reaction of a chloromethylene compound with a 1-methylisatin When examined m the mass spectrometer the expected ion reactions were observed and, in addition, a reaction involving expulsion of the carbonyl group of the oxindole moiety and rearrangement of the residual fragment, to give a 1-methylbenzo[b]azepinium ion was observed. The anions of the oxindolidyluracilmethines 4 and 5, (R = Me, R′ = OH) had an absorption band near 380 mμ but the corresponding neutral molecules absorbed at 325–350 mμ. The 5-nitrofuran derivatives 3 were the only compounds that inhibited the growth of Bacillus subtilis.
2010 ◽
Vol 46
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pp. 936-937
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1967 ◽
Vol 13
(12)
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pp. 1577-1589
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Keyword(s):
1980 ◽
Vol 26
(4)
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pp. 255-263
1973 ◽
Vol 113
(2)
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pp. 739-753
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